Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes (Q35748146)

10 August 2017

title

Expression profiling of pancreatic beta cells: glucose regulation of secretory and metabolic pathway genes (English)

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10 August 2017

1 reference

G C Webb

1

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10 August 2017

M S Akbar

series ordinal

2

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10 August 2017

C Zhao

series ordinal

3

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10 August 2017

D F Steiner

series ordinal

4

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10 August 2017

language of work or name

English

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publication date

1 May 2000

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

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10 August 2017

volume

97

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10 August 2017

issue

11

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10 August 2017

page(s)

5773-5778

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Long-term elevation of free fatty acids leads to delayed processing of proinsulin and prohormone convertases 2 and 3 in the pancreatic beta-cell line MIN6.

10 August 2017

cites work

1 reference

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Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

12 July 2018

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Induction of gadd153 mRNA by nutrient deprivation is overcome by glutamine

12 July 2018

1 reference

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Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion

12 July 2018

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Folding of insulin receptor monomers is facilitated by the molecular chaperones calnexin and calreticulin and impaired by rapid dimerization

12 July 2018

1 reference

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Type 2 Diabetes: When Insulin Secretion Fails to Compensate for Insulin Resistance

12 July 2018

1 reference

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Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Insulin mediates glucose-stimulated phosphorylation of PHAS-I by pancreatic beta cells. An insulin-receptor mechanism for autoregulation of protein synthesis by translation

12 July 2018

1 reference

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Glucokinase mutations, insulin secretion, and diabetes mellitus

12 July 2018

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Genetics of non-insulin-dependent (type-II) diabetes mellitus

12 July 2018

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Insulin-secreting cell lines: classification, characteristics and potential applications.

12 July 2018

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Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells

12 July 2018

1 reference

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Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line

12 July 2018

1 reference

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Regulation of the C/EBP-related gene gadd153 by glucose deprivation

12 July 2018

1 reference

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Protein translocation into proteoliposomes reconstituted from purified components of the endoplasmic reticulum membrane

12 July 2018

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Protein translocation across the endoplasmic reticulum. II. Isolation and characterization of the signal recognition particle receptor

12 July 2018

1 reference

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C-peptide immunoreactivity and insulin content in the diabetic human pancreas and the relation to the stability of diabetic serum glucose level.

12 July 2018

1 reference

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Translational control of insulin biosynthesis. Evidence for regulation of elongation, initiation and signal-recognition-particle-mediated translational arrest by glucose.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Regulation of glucokinase and GLUT-2 glucose-transporter gene expression in pancreatic B-cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Biochemical fractionation and assembly of the membrane components that mediate nascent chain targeting and translocation

12 July 2018

1 reference

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Structural domains and molecular lifestyles of insulin and its precursors in the pancreatic beta cell

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Differences in glucose recognition by individual rat pancreatic B cells are associated with intercellular differences in glucose-induced biosynthetic activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Tissue-specific regulation of glucokinase gene expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

A mammalian homolog of SEC61p and SECYp is associated with ribosomes and nascent polypeptides during translocation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

The signal sequence receptor, unlike the signal recognition particle receptor, is not essential for protein translocation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

12 July 2018

1 reference

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Exercise training in Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus: effects on the B-cell mass, insulin content and fibrosis in the pancreas

25 September 2018

1 reference

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Simplified northern blot hybridization using 5% sodium dodecyl sulfate

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18509

Pancreatic beta cell heterogeneity in glucose-induced insulin secretion

6 December 2018

1 reference

12 December 2020

The biosynthesis of the subtilisin-related proprotein convertase PC3, but no that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets

1 reference

12 December 2020

Parallel reduction of pancreas insulin content and insulin secretion in 48-h tolbutamide-infused normoglycemic rats

1 reference

12 December 2020

Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion

1 reference

12 December 2020

Direct effect of glucose on the preproinsulin mRNA level in isolated pancreatic islets

1 reference

12 December 2020

Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability

1 reference

12 December 2020

Translational control of proinsulin synthesis by glucose

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.100126597

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10 August 2017

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10 August 2017

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