Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis (Q35745175)

10 August 2017

title

Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis (English)

1 reference

10 August 2017

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Theodosia A Kalfa

13

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Anil G. Jegga

object named as

Anil G Jegga

8

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Jeffery D. Molkentin

object named as

Jeffery D Molkentin

11

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Bruce J Aronow

10

object named as

Bruce J Aronow

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10 August 2017

Abhinav Diwan

1

1 reference

10 August 2017

Andrew G Koesters

2

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10 August 2017

Amy M Odley

3

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10 August 2017

Suvarnamala Pushkaran

4

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10 August 2017

Christopher P Baines

5

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10 August 2017

Benjamin T Spike

6

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10 August 2017

Diedre Daria

7

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10 August 2017

Hartmut Geiger

9

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10 August 2017

Kay F Macleod

12

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10 August 2017

Gerald W Dorn

14

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10 August 2017

language of work or name

English

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publication date

9 April 2007

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Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

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10 August 2017

volume

104

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10 August 2017

issue

16

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10 August 2017

page(s)

6794-6799

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JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis

10 August 2017

cites work

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Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia

12 July 2018

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Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress

12 July 2018

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Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis

12 July 2018

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Combined loss of proapoptotic genes Bak or Bax with Bim synergizes to cause defects in hematopoiesis and in thymocyte apoptosis

12 July 2018

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A gain-of-function mutation of JAK2 in myeloproliferative disorders

12 July 2018

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A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera

12 July 2018

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12 July 2018

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The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation

12 July 2018

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12 July 2018

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

12 July 2018

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Ineffective erythropoiesis in Stat5a(-/-)5b(-/-) mice due to decreased survival of early erythroblasts

12 July 2018

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BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

12 July 2018

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HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.

12 July 2018

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Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

12 July 2018

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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

12 July 2018

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Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction

12 July 2018

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Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly

12 July 2018

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The monoclonal antibody TER-119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage

12 July 2018

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Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

12 July 2018

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Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability

12 July 2018

1 reference

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Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

12 July 2018

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The Erythropoietin Receptor: Structure, Activation and Intracellular Signal Transduction.

12 July 2018

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Apoptotic role of Fas/Fas ligand system in the regulation of erythropoiesis

12 July 2018

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Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins

12 July 2018

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Bax directly induces release of cytochrome c from isolated mitochondria

12 July 2018

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Expression of Bcl-x in Erythroid Precursors from Patients with Polycythemia Vera

12 July 2018

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Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

12 July 2018

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Thrombopoietin rescues in vitro erythroid colony formation from mouse embryos lacking the erythropoietin receptor

12 July 2018

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Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

12 July 2018

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Transactivation of the adenovirus EIIa promoter in the absence of adenovirus E1A protein is restricted to mouse oocytes and preimplantation embryos

12 July 2018

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Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1849960

Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1849960

Apoptosis protection by the Epo target Bcl-X(L) allows factor-independent differentiation of primary erythroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1849960

Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1849960

Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1849960

GATA-1 and erythropoietin cooperate to promote erythroid cell survival by regulating bcl-xL expression.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1849960

Apoptosis in Relation to CD34 Antigen Expression in Normal and Myelodysplastic Bone Marrow

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0610666104

Widespread recombinase expression using FLPeR (flipper) mice

21 January 2018

1 reference

12 December 2020

Survival or death of individual proerythroblasts results from differing erythropoietin sensitivities: a mechanism for controlled rates of erythrocyte production

1 reference

12 December 2020

Expression of growth factor receptors in unilineage differentiation culture of purified hematopoietic progenitors

1 reference

12 December 2020

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

12 December 2020

Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0610666104

1 reference

10 August 2017

0 references

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10 August 2017

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