The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function (Q35729931)

9 August 2017

title

The tethered configuration of the EGF receptor extracellular domain exerts only a limited control of receptor function (English)

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9 August 2017

3

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9 August 2017

5

Joseph Schlessinger

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9 August 2017

Dawn Mattoon

1

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9 August 2017

Peter Klein

series ordinal

2

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9 August 2017

Irit Lax

series ordinal

4

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9 August 2017

language of work or name

English

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publication date

19 January 2004

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Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

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9 August 2017

volume

101

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9 August 2017

issue

4

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9 August 2017

page(s)

923-928

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A structure-based model for ligand binding and dimerization of EGF receptors

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors

12 July 2018

1 reference

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Epidermal growth factor receptor: mechanisms of activation and signalling.

12 July 2018

1 reference

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab

12 July 2018

1 reference

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A putative molecular-activation switch in the transmembrane domain of erbB2.

12 July 2018

1 reference

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Ligand-induced, receptor-mediated dimerization and activation of EGF receptor

12 July 2018

1 reference

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Structure of the extracellular region of HER3 reveals an interdomain tether

12 July 2018

1 reference

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Structural basis for autoinhibition of the Ephb2 receptor tyrosine kinase by the unphosphorylated juxtamembrane region

12 July 2018

1 reference

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Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.

12 July 2018

1 reference

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Oncogenic kinase signalling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Combinatorial control of the specificity of protein tyrosine phosphatases

12 July 2018

1 reference

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Cell signaling by receptor tyrosine kinases

12 July 2018

1 reference

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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

12 July 2018

1 reference

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Two EGF molecules contribute additively to stabilization of the EGFR dimer

12 July 2018

1 reference

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

12 July 2018

1 reference

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Hierarchy of binding sites for Grb2 and Shc on the epidermal growth factor receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Biological activities of EGF-receptor mutants with individually altered autophosphorylation sites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Kinetic parameters of the protein tyrosine kinase activity of EGF-receptor mutants with individually altered autophosphorylation sites

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Functional analysis of the ligand binding site of EGF-receptor utilizing chimeric chicken/human receptor molecules.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

Interpretation of Scatchard plots for aggregating receptor systems

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=327118

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

12 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0307286101

Thermodynamic mixing of molecular states of the epidermal growth factor receptor modulates macroscopic ligand binding affinity

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0307286101

Signal transduction. Autoinhibition control

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073/PNAS.0307286101

21 January 2018

Identifiers

DOI

10.1073/PNAS.0307286101

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9 August 2017

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9 August 2017

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