Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes (Q35724421)

9 August 2017

title

Prospects for In Vitro Myofilament Maturation in Stem Cell-Derived Cardiac Myocytes (English)

1 reference

9 August 2017

Jonas Schwan

1

1 reference

9 August 2017

Stuart G Campbell

series ordinal

2

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9 August 2017

publication date

10 June 2015

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9 August 2017

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9 August 2017

volume

10

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9 August 2017

issue

Suppl 1

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9 August 2017

page(s)

91-103

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Current status of induced pluripotent stem cells in cardiac tissue regeneration and engineering

9 August 2017

cites work

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12 July 2018

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12 July 2018

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Divergent effects of α- and β-myosin heavy chain isoforms on the N terminus of rat cardiac troponin T.

12 July 2018

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12 July 2018

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Altered ventricular torsion and transmural patterns of myocyte relaxation precede heart failure in aging F344 rats

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Patient-specific induced-pluripotent stem cells-derived cardiomyocytes recapitulate the pathogenic phenotypes of dilated cardiomyopathy due to a novel DES mutation identified by whole exome sequencing.

12 July 2018

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Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

12 July 2018

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12 July 2018

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Murine and human pluripotent stem cell-derived cardiac bodies form contractile myocardial tissue in vitro

12 July 2018

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Increased afterload induces pathological cardiac hypertrophy: a new in vitro model

12 July 2018

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Effects of R92 mutations in mouse cardiac troponin T are influenced by changes in myosin heavy chain isoform

12 July 2018

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12 July 2018

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Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease

12 July 2018

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Application of human stem cell-derived cardiomyocytes in safety pharmacology requires caution beyond hERG.

12 July 2018

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12 July 2018

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Dantrolene rescues arrhythmogenic RYR2 defect in a patient-specific stem cell model of catecholaminergic polymorphic ventricular tachycardia

12 July 2018

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Cardiomyocytes generated from CPVTD307H patients are arrhythmogenic in response to β-adrenergic stimulation

12 July 2018

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Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology

12 July 2018

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Calcium homeostasis in human induced pluripotent stem cell-derived cardiomyocytes

12 July 2018

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Growth of Engineered Human Myocardium With Mechanical Loading and Vascular Coculture

12 July 2018

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12 July 2018

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Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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The giant protein titin as an integrator of myocyte signaling pathways

12 July 2018

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12 July 2018

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Cardiac titin: a multifunctional giant

12 July 2018

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Nongenetic method for purifying stem cell-derived cardiomyocytes

12 July 2018

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Global expression profile of highly enriched cardiomyocytes derived from human embryonic stem cells

12 July 2018

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Titin-based mechanical signalling in normal and failing myocardium

12 July 2018

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Absence of transverse tubules contributes to non-uniform Ca(2 ) wavefronts in mouse and human embryonic stem cell-derived cardiomyocytes.

12 July 2018

1 reference

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Force frequency relationship of the human ventricle increases during early postnatal development

12 July 2018

1 reference

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Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes

12 July 2018

1 reference

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Human embryonic stem cells for cardiomyogenesis

12 July 2018

1 reference

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Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone

12 July 2018

1 reference

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Identification of cardiac-specific myosin light chain kinase

12 July 2018

1 reference

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The unique functions of cardiac troponin I in the control of cardiac muscle contraction and relaxation

12 July 2018

1 reference

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Extracellular matrix, mechanotransduction and structural hierarchies in heart tissue engineering

12 July 2018

1 reference

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Heart failure, ischemia/reperfusion injury and cardiac troponin

12 July 2018

1 reference

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Crucial role of the sarcoplasmic reticulum in the developmental regulation of Ca2 transients and contraction in cardiomyocytes derived from embryonic stem cells.

12 July 2018

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Calcium, thin filaments, and the integrative biology of cardiac contractility

12 July 2018

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Basal myosin light chain phosphorylation is a determinant of Ca2 sensitivity of force and activation dependence of the kinetics of myocardial force development

12 July 2018

1 reference

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Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy

12 July 2018

1 reference

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The giant protein titin: a major player in myocardial mechanics, signaling, and disease

12 July 2018

1 reference

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Modulation of thin filament activation by breakdown or isoform switching of thin filament proteins: physiological and pathological implications

12 July 2018

1 reference

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Structure of the core domain of human cardiac troponin in the Ca(2 )-saturated form

12 July 2018

1 reference

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The human adult cardiomyocyte phenotype.

12 July 2018

1 reference

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Cardiac excitation-contraction coupling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Skeletal and cardiac muscle contractile activation: tropomyosin "rocks and rolls".

12 July 2018

1 reference

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Myosin heavy chain isoform expression in the failing and nonfailing human heart

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Cardiac myosin binding protein C

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Myosin light chain 2a and 2v identifies the embryonic outflow tract myocardium in the developing rodent heart

12 July 2018

1 reference

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Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Effects of total replacement of atrial myosin light chain-2 with the ventricular isoform in atrial myocytes of transgenic mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Myosin heavy chain gene expression in human heart failure

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Contractile protein phenotypic variation during development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Phosphorylation of both serine residues in cardiac troponin I is required to decrease the Ca2 affinity of cardiac troponin C.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Troponin I gene expression during human cardiac development and in end-stage heart failure

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Structure of the actin-myosin complex and its implications for muscle contraction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Alpha-tropomyosin and cardiac troponin T mutations cause familial hypertrophic cardiomyopathy: a disease of the sarcomere

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Transition in cardiac contractile sensitivity to calcium during the in vitro differentiation of mouse embryonic stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signals

12 July 2018

1 reference

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Characterization of human cardiac myosin heavy chain genes

12 July 2018

1 reference

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Developmental regulation of myosin gene expression in mouse cardiac muscle

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Differential regulation of the atrial isoforms of the myosin light chains during striated muscle development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Phosphorylation of the inhibitory subunit of troponin and its effect on the calcium dependence of cardiac myofibril adenosine triphosphatase

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Myosin isoenzyme redistribution in chronic heart overload

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Modeling of Friedreich ataxia-related iron overloading cardiomyopathy using patient-specific-induced pluripotent stem cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Exon skipping and gene transfer restore dystrophin expression in human induced pluripotent stem cells-cardiomyocytes harboring DMD mutations

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Generation of patient-specific induced pluripotent stem cell-derived cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Ca²⁺ channel activators reveal differential L-type Ca²⁺ channel pharmacology between native and stem cell-derived cardiomyocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Development of a drug screening platform based on engineered heart tissue

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Thyroid hormone regulates developmental titin isoform transitions via the phosphatidylinositol-3-kinase/ AKT pathway

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Functional and developmental properties of human embryonic stem cells-derived cardiomyocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Cardiac troponin I threonine 144: role in myofilament length dependent activation

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2 handling and the role of sarcoplasmic reticulum in the contraction

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Power output is linearly related to MyHC content in rat skinned myocytes and isolated working hearts

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Developmentally regulated switching of titin size alters myofibrillar stiffness in the perinatal heart

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Developmental control of titin isoform expression and passive stiffness in fetal and neonatal myocardium

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Small amounts of alpha-myosin heavy chain isoform expression significantly increase power output of rat cardiac myocyte fragments

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Loaded shortening and power output in cardiac myocytes are dependent on myosin heavy chain isoform expression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Human cardiac myosin heavy chain isoforms in fetal and failing adult atria and ventricles

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Postnatal myosin heavy chain isoform expression in normal mice and mice null for IIb or IId myosin heavy chains

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Phosphorylation-induced distance change in a cardiac muscle troponin I mutant.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Tension production and thin-filament protein isoforms in developing rat myocardium.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Myosin isoenzymes in normal and hypertrophied human ventricular myocardium

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Myosin changes in hypertrophied human atrial and ventricular myocardium. A correlated immunofluorescence and quantitative immunochemical study on serial cryosections

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463797

Existence of the Frank-Starling mechanism in the failing human heart. Investigations on the organ, tissue, and sarcomere levels

15 November 2018

1 reference

12 December 2020

Hormonal regulation of myosin heavy chain and alpha-actin gene expression in cultured fetal rat heart myocytes

1 reference

12 December 2020

Full-length rat alpha and beta cardiac myosin heavy chain sequences. Comparisons suggest a molecular basis for functional differences

1 reference

12 December 2020

Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity

1 reference

12 December 2020

Force-pCa relation and troponin T isoforms of rabbit myocardium

1 reference

12 December 2020

Applications of human-induced pluripotent stem cells in the investigation of inherited cardiomyopathy

1 reference

12 December 2020

Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heart

1 reference

12 December 2020

Sarcomere length dependence of rat skinned cardiac myocyte mechanical properties: dependence on myosin heavy chain

1 reference

12 December 2020

Altered myocardial force-frequency relation in human heart failure

1 reference

12 December 2020

Abnormal frequency-dependent responses represent the pathophysiologic signature of contractile failure in human myocardium

1 reference

12 December 2020

The economy of isometric force development, myosin isoenzyme pattern and myofibrillar ATPase activity in normal and hypothyroid rat myocardium

1 reference

12 December 2020

Reconstitution of troponin activity from three protein components

1 reference

12 December 2020

Expression of the cardiac ventricular alpha- and beta-myosin heavy chain genes is developmentally and hormonally regulated

1 reference

12 December 2020

Distribution pattern of alpha and beta myosin in normal and diseased human ventricular myocardium

1 reference

12 December 2020

Identifiers

DOI

10.4137/BMI.S23912

1 reference

9 August 2017

1 reference

9 August 2017

1 reference