IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression (Q35713747)

9 August 2017

title

IKKα activation of NOTCH links tumorigenesis via FOXA2 suppression (English)

1 reference

9 August 2017

17

Michael Karin

1 reference

9 August 2017

19

Mien-Chie Hung

1 reference

9 August 2017

14

Chao-Kai Chou

1 reference

9 August 2017

2

Dung-Fang Lee

1 reference

9 August 2017

11

Weiya Xia

1 reference

9 August 2017

12

Yongkun Wei

1 reference

9 August 2017

6

Hong-Jen Lee

1 reference

9 August 2017

9

Jung-Mao Hsu

1 reference

9 August 2017

10

Hsu-Ping Kuo

1 reference

9 August 2017

4

Chia-Jui Yen

1 reference

9 August 2017

13

Pei-Chun Chiu

1 reference

9 August 2017

Mo Liu

1

1 reference

9 August 2017

Chun-Te Chen

3

1 reference

9 August 2017

Long-Yuan Li

5

1 reference

9 August 2017

Chun-Ju Chang

7

1 reference

9 August 2017

Wei-Chao Chang

8

1 reference

9 August 2017

Yi Du

15

1 reference

9 August 2017

Debanjan Dhar

16

1 reference

9 August 2017

Chung-Hsuan Chen

18

1 reference

9 August 2017

publication date

22 December 2011

1 reference

9 August 2017

1 reference

9 August 2017

volume

45

1 reference

9 August 2017

issue

2

1 reference

9 August 2017

page(s)

171-184

1 reference

Two novel human NUMB isoforms provide a potential link between development and cancer

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Residual hepatocellular carcinoma after oxaliplatin treatment has increased metastatic potential in a nude mouse model and is attenuated by Songyou Yin.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Inflammatory bowel disease and intestinal cancer: a paradigm of the Yin-Yang interplay between inflammation and cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Alterations of the Notch pathway in lung cancer.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Down-regulation of Notch1 signaling inhibits tumor growth in human hepatocellular carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Advances in targeting IKK and IKK-related kinases for cancer therapy

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Pathways connecting inflammation and cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

The IkappaB kinase - a bridge between inflammation and cancer

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

ERK promotes tumorigenesis by inhibiting FOXO3a via MDM2-mediated degradation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

IKK beta suppression of TSC1 links inflammation and tumor angiogenesis via the mTOR pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Controls of germline stem cells, entry into meiosis, and the sperm/oocyte decision in Caenorhabditis elegans

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Regulation of lymphocyte development by Notch signaling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing Maspin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

The hepatocyte nuclear factor 6 (HNF6) and FOXA2 are key regulators in colorectal liver metastases

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Kaposi's Sarcoma-associated herpesvirus lytic switch protein stimulates DNA binding of RBP-Jk/CSL to activate the Notch pathway

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

IKKalpha stabilizes cytosolic beta-catenin by inhibiting both canonical and non-canonical degradation pathways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Foxa2 is required for the differentiation of pancreatic alpha-cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Notch1 signaling inhibits growth of human hepatocellular carcinoma through induction of cell cycle arrest and apoptosis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Role of Foxa-2 in adipocyte metabolism and differentiation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Identification of patterns in biological sequences at the ALGGEN server: PROMO and MALGEN.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

PROMO: detection of known transcription regulatory elements using species-tailored searches

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Inflammation and cancer: back to Virchow?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Liver enriched transcription factors and differentiation of hepatocellular carcinoma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Truncated mammalian Notch1 activates CBF1/RBPJk-repressed genes by a mechanism resembling that of Epstein-Barr virus EBNA2

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Intersections between pulmonary development and disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Notch-1 associates with IKKalpha and regulates IKK activity in cervical cancer cells.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

HES and HERP families: multiple effectors of the Notch signaling pathway

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3268914

H. pylori activates NF-kappaB through a signaling pathway involving IkappaB kinases, NF-kappaB-inducing kinase, TRAF2, and TRAF6 in gastric cancer cells

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22196886

12 December 2020

inferred from PubMed ID database lookup

T cell acute lymphoblastic leukemia: NOTCHing the way toward a better treatment outcome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22196886

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.MOLCEL.2011.11.018

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kbdjehcghzebladjin34eduk3u

30 July 2022

release_kbdjehcghzebladjin34eduk3u

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kbdjehcghzebladjin34eduk3u

30 July 2022

https://api.fatcat.wiki/v0/release/kbdjehcghzebladjin34eduk3u

1 reference

30 July 2022

https://api.fatcat.wiki/v0/release/kbdjehcghzebladjin34eduk3u

1 reference

30 July 2022