Molecular regulations governing TREK and TRAAK channel functions. (Q35693711)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

review article

1 reference

title

Molecular regulations governing TREK and TRAAK channel functions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

Guillaume Sandoz

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

Florian Lesage

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

author name string

Jacques Noël

1

1 reference

9 August 2017

Guillaume Sandoz

2

1 reference

9 August 2017

Florian Lesage

3

1 reference

9 August 2017

publication date

1 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

volume

5

1 reference

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10 February 2020

issue

5

1 reference

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10 February 2020

page(s)

402-409

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

Oxaliplatin-induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors.

10 February 2020

cites work

1 reference

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Optical probing of a dynamic membrane interaction that regulates the TREK1 channel

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Expression of Stretch-Activated Two-Pore Potassium Channels in Human Myometrium in Pregnancy and Labor

27 July 2018

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27 July 2018

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Molecular background of leak K currents: two-pore domain potassium channels

27 July 2018

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27 July 2018

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27 July 2018

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Expression of transient receptor potential channels and two-pore potassium channels in subtypes of vagal afferent neurons in rat

27 July 2018

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Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue.

27 July 2018

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Inhibition of human two-pore domain K channel TREK1 by local anesthetic lidocaine: negative cooperativity and half-of-sites saturation kinetics

27 July 2018

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TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices

27 July 2018

1 reference

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A structural model for K2P potassium channels based on 23 pairs of interacting sites and continuum electrostatics

27 July 2018

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Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K channels

27 July 2018

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Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion

27 July 2018

1 reference

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Alternative translation initiation in rat brain yields K2P2.1 potassium channels permeable to sodium

27 July 2018

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Two-pore potassium channels in the cardiovascular system

27 July 2018

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TREK-1 is a novel molecular target in prostate cancer

27 July 2018

1 reference

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Methionine and its derivatives increase bladder excitability by inhibiting stretch-dependent K( ) channels

27 July 2018

1 reference

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Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel

27 July 2018

1 reference

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Up- and down-regulation of the mechano-gated K(2P) channel TREK-1 by PIP (2) and other membrane phospholipids.

27 July 2018

1 reference

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Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link

27 July 2018

1 reference

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A Ba2 -resistant, acid-sensitive K conductance in Na -absorbing H441 human airway epithelial cells.

27 July 2018

1 reference

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AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K( ) channels into open leak channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Neuronal two-pore-domain potassium channels and their regulation by G protein-coupled receptors

27 July 2018

1 reference

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TREK-1, a K channel involved in polymodal pain perception

27 July 2018

1 reference

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Desensitization of mechano-gated K2P channels

27 July 2018

1 reference

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International Union of Pharmacology. LIV. Nomenclature and Molecular Relationships of Inwardly Rectifying Potassium Channels

27 July 2018

1 reference

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International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels

27 July 2018

1 reference

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The stretch-activated potassium channel TREK-1 in rat cardiac ventricular muscle

27 July 2018

1 reference

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Two-pore-domain potassium channels in smooth muscles: new components of myogenic regulation

27 July 2018

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Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels

27 July 2018

1 reference

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Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton.

27 July 2018

1 reference

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Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine

27 July 2018

1 reference

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A phospholipid sensor controls mechanogating of the K channel TREK-1.

27 July 2018

1 reference

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TREK-1, a K channel involved in neuroprotection and general anesthesia

27 July 2018

1 reference

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Functional evidence of a role for two-pore domain potassium channels in rat mesenteric and pulmonary arteries.

27 July 2018

1 reference

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Sortilin is essential for proNGF-induced neuronal cell death

27 July 2018

1 reference

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Two-pore-domain K channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane

27 July 2018

1 reference

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Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K channels

27 July 2018

1 reference

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Inhibition of human TREK-1 channels by bupivacaine

27 July 2018

1 reference

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Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals

27 July 2018

1 reference

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An ACTH- and ATP-regulated background K channel in adrenocortical cells is TREK-1

27 July 2018

1 reference

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Cloning of two transcripts, HKT4.1a and HKT4.1b, from the human two-pore K channel gene KCNK4. Chromosomal localization, tissue distribution and functional expression

27 July 2018

1 reference

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An intracellular proton sensor commands lipid- and mechano-gating of the K( ) channel TREK-1.

27 July 2018

1 reference

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Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2

27 July 2018

1 reference

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Localization of TREK-2 K channel domains that regulate channel kinetics and sensitivity to pressure, fatty acids and pHi.

27 July 2018

1 reference

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Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

27 July 2018

1 reference

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A TREK-1-like potassium channel in atrial cells inhibited by beta-adrenergic stimulation and activated by volatile anesthetics

27 July 2018

1 reference

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Lipid and mechano-gated 2P domain K( ) channels.

27 July 2018

1 reference

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Synergistic interaction and the role of C-terminus in the activation of TRAAK K channels by pressure, free fatty acids and alkali

27 July 2018

1 reference

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Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery

27 July 2018

1 reference

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Human TREK2, a 2P domain mechano-sensitive K channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors

27 July 2018

1 reference

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TREK-1 is a heat-activated background K( ) channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

The neuroprotective agent riluzole activates the two P domain K( ) channels TREK-1 and TRAAK

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Polyunsaturated fatty acids are potent neuroprotectors

27 July 2018

1 reference

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Cloning and expression of human TRAAK, a polyunsaturated fatty acids-activated and mechano-sensitive K( ) channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

TREK-2, a new member of the mechanosensitive tandem-pore K channel family

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Lysophospholipids open the two-pore domain mechano-gated K( ) channels TREK-1 and TRAAK.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Inhalational anesthetics activate two-pore-domain background K channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

TRAAK is a mammalian neuronal mechano-gated K channel.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

A neuronal two P domain K channel stimulated by arachidonic acid and polyunsaturated fatty acids.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Cloning, functional expression and brain localization of a novel unconventional outward rectifier K channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Dimerization of TWIK-1 K channel subunits via a disulfide bridge

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

TWIK-1, a ubiquitous human weakly inward rectifying K channel with a novel structure

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Trafficking of neuronal two pore domain potassium channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Activation of TREK currents by the neuroprotective agent riluzole in mouse sympathetic neurons.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

The stretch-dependent potassium channel TREK-1 and its function in murine myometrium

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

The membrane-bound state of K2P potassium channels

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K channels

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

The mechano-activated K channels TRAAK and TREK-1 control both warm and cold perception

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Intracellular traffic of the K channels TASK-1 and TASK-3: role of N- and C-terminal sorting signals and interaction with 14-3-3 proteins

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Protein complex analysis of native brain potassium channels by proteomics.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Control of the single channel conductance of K2P10.1 (TREK-2) by the amino-terminus: role of alternative translation initiation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Mtap2 is a constituent of the protein network that regulates twik-related K channel expression and trafficking.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Temperature-sensitive TREK currents contribute to setting the resting membrane potential in embryonic atrial myocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

A novel mechanism for human K2P2.1 channel gating. Facilitation of C-type gating by protonation of extracellular histidine residues

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Changes in expression of some two-pore domain potassium channel genes (KCNK) in selected brain regions of developing mice.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

mGlu4 potentiation of K(2P)2.1 is dependant on C-terminal dephosphorylation.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Antipsychotics inhibit TREK but not TRAAK channels.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

TREK-2 (K2P10.1) and TRESK (K2P18.1) are major background K channels in dorsal root ganglion neurons

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Angiotensin II inhibits bTREK-1 K channels in adrenocortical cells by separate Ca2 - and ATP hydrolysis-dependent mechanisms

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Thermosensitivity of the two-pore domain K channels TREK-2 and TRAAK

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K channels.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

TREK-1 K channels couple angiotensin II receptors to membrane depolarization and aldosterone secretion in bovine adrenal glomerulosa cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Characterization of four types of background potassium channels in rat cerebellar granule neurons

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Functional expression of TREK-2 K channel in cultured rat brain astrocytes

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

The endocannabinoid anandamide is a direct and selective blocker of the background K( ) channel TASK-1.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

A mammalian two pore domain mechano-gated S-like K channel

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3265763

GENE EXPRESSION OF STRETCH-ACTIVATED CHANNELS AND MECHANOELECTRIC FEEDBACK IN THE HEART

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.4161/CHAN.5.5.16469

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21829087

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of stretch-activated potassium channels in human myometrium

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21829087

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mechanism of inhibition of TREK-2 (K2P10.1) by the Gq-coupled M3 muscarinic receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21829087

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4161/CHAN.5.5.16469

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21829087 AND SRC:MED&resulttype=core&format=json

10 February 2020

1 reference