Therapeutic antibodies against CGRP or its receptor (Q35684794)

9 August 2017

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title

Therapeutic antibodies against CGRP or its receptor (English)

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9 August 2017

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1

Marcelo E Bigal

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9 August 2017

Sarah Walter

2

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9 August 2017

Alan M Rapoport

series ordinal

3

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9 August 2017

language of work or name

English

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publication date

1 June 2015

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British Journal of Clinical Pharmacology

9 August 2017

published in

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9 August 2017

volume

79

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9 August 2017

issue

6

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9 August 2017

page(s)

886-895

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Safety and efficacy of ALD403, an antibody to calcitonin gene-related peptide, for the prevention of frequent episodic migraine: a randomised, double-blind, placebo-controlled, exploratory phase 2 trial

9 August 2017

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Evaluation of cardiovascular parameters in cynomolgus monkeys following IV administration of LBR-101, a monoclonal antibody against calcitonin gene-related peptide

12 July 2018

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Monoclonal antibodies for migraine: preventing calcitonin gene-related peptide activity

12 July 2018

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Calcitonin gene-related peptide (CGRP) and migraine current understanding and state of development

12 July 2018

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Emerging target-based paradigms to prevent and treat migraine

12 July 2018

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Two mechanisms involved in trigeminal CGRP release: implications for migraine treatment

12 July 2018

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Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society

12 July 2018

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Diencephalic and brainstem mechanisms in migraine

12 July 2018

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CGRP: sensory neuropeptide with multiple neurologic implications

12 July 2018

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New drugs in migraine treatment and prophylaxis: telcagepant and topiramate

12 July 2018

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Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine

12 July 2018

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Migraine in the triptan era: lessons from epidemiology, pathophysiology, and clinical science

12 July 2018

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Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

12 July 2018

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Inhibition of calcitonin gene-related peptide function: a promising strategy for treating migraine

12 July 2018

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Clinical course in migraine: conceptualizing migraine transformation

12 July 2018

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History of methysergide in migraine

12 July 2018

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Early development of therapeutic biologics--pharmacokinetics.

12 July 2018

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Calcitonin gene-related peptide antagonists as treatments of migraine and other primary headaches

12 July 2018

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Somatosensory evoked high-frequency oscillations reflecting thalamo-cortical activity are decreased in migraine patients between attacks

12 July 2018

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Calcitonin gene-related peptide (CGRP) modulates nociceptive trigeminovascular transmission in the cat.

12 July 2018

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Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine

12 July 2018

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The International Classification of Headache Disorders: 2nd edition

12 July 2018

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New onset migraine with a brain stem cavernous angioma

12 July 2018

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CGRP may play a causative role in migraine

12 July 2018

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Migraine--current understanding and treatment

12 July 2018

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Modification of vasoconstrictor responses in cerebral blood vessels by lesioning of the trigeminal nerve: possible involvement of CGRP.

12 July 2018

1 reference

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Neurogenic inflammation in the pathophysiology and treatment of migraine.

12 July 2018

1 reference

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Neocortical spreading depression provokes the expression of c-fos protein-like immunoreactivity within trigeminal nucleus caudalis via trigeminovascular mechanisms.

12 July 2018

1 reference

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Pathophysiology of the migraine aura. The spreading depression theory

12 July 2018

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Brain stem activation in spontaneous human migraine attacks

12 July 2018

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What is migraine? Controversy and stalemate in migraine pathophysiology

12 July 2018

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Safety and efficacy of LY2951742, a monoclonal antibody to calcitonin gene-related peptide, for the prevention of migraine: a phase 2, randomised, double-blind, placebo-controlled study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: Results of the Phase 1 program

25 September 2018

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Differentiation of nerve fibers storing CGRP and CGRP receptors in the peripheral trigeminovascular system

25 September 2018

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Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults: report of the Quality Standards subcommittee of the American Academy of Neurology and the American Headache Society

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Effect of the calcitonin gene-related peptide (CGRP) receptor antagonist telcagepant in human cranial arteries

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Further observations on the spreading depression of activity in the cerebral cortex

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

25 September 2018

10 years of rizatriptan

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

The hypothalamus in migraine

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Chronic migraine in the population: burden, diagnosis, and satisfaction with treatment

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Interictal habituation deficit of the nociceptive blink reflex: an endophenotypic marker for presymptomatic migraine?

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Symptomatic migraine and pontine vascular malformation: evidence for a key role of the brainstem in the pathophysiology of chronic migraine

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

A positron emission tomographic study in spontaneous migraine.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

The slow voltage variation of cortical spreading depression of activity

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Neurovascular headache and a midbrain vascular malformation: evidence for a role of the brainstem in chronic migraine

25 September 2018

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Migraine in the United States: epidemiology and patterns of health care use.

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Brainstem activation specific to migraine headache

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Migraine, quality of life, and depression: a population-based case-control study

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

The impact of migraine on quality of life in the general population: the GEM study

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4456121

Cardiovascular and hemodynamic parameters in women following prolonged CGRP inhibition using LBR-101, a monoclonal antibody against CGRP

25 September 2018

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12 December 2020

Release of vasoactive peptides in the extracerebral circulation of humans and the cat during activation of the trigeminovascular system

1 reference

12 December 2020

The development of neurogenic plasma extravasation in the rat dura mater does not depend upon the degranulation of mast cells

1 reference

12 December 2020

Patterns of use and reasons for discontinuation of prophylactic medications for episodic migraine and chronic migraine: results from the second international burden of migraine study (IBMS-II)

1 reference

12 December 2020

The calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS reduces neurogenic increases in dural blood flow

1 reference

12 December 2020

Headache caused by a single lesion of multiple sclerosis in the periaqueductal gray area

1 reference

12 December 2020

CGRP: blood flow and more?

1 reference

12 December 2020

Peripheral CGRP release as a marker for neurogenic inflammation: a model system for the study of neuropeptide secretion in rat paw skin

1 reference

12 December 2020

CGRP-receptor antagonism in migraine treatment

1 reference

12 December 2020

Identifiers

DOI

10.1111/BCP.12591

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9 August 2017

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9 August 2017

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