Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells. (Q35681914)

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scientific article published on July 2011

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English	Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells.	scientific article published on July 2011

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723843 AND SRC:MED&resulttype=core&format=json

6 February 2020

Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21723843 AND SRC:MED&resulttype=core&format=json

6 February 2020

apoptotic process

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endoplasmic reticulum

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multiple myeloma

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based on heuristic

inferred from title

Deborah L. Galson

2

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6 February 2020

author name string

Feng-Ming Wang

1

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6 February 2020

G David Roodman

3

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6 February 2020

Hongjiao Ouyang

4

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6 February 2020

publication date

1 July 2011

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6 February 2020

Experimental Hematology

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6 February 2020

39

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6 February 2020

10

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6 February 2020

999-1006

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Europe PubMed Central

PMC publication ID

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6 February 2020

SIRT1: recent lessons from mouse models.

1 reference

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12 July 2018

Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation

1 reference

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Transcriptional and post-transcriptional regulation of proangiogenic factors by the unfolded protein response

1 reference

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12 July 2018

HSP72 protects cells from ER stress-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction

1 reference

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The UPR and cell fate at a glance

1 reference

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The role of X-box binding protein-1 in tumorigenicity.

1 reference

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12 July 2018

Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

The endoplasmic reticulum stress response in immunity and autoimmunity

1 reference

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Cancer chemoprevention through dietary antioxidants: progress and promise

1 reference

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12 July 2018

Endoplasmic reticulum stress in disease pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

IRE1 signaling affects cell fate during the unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Heat shock protein inhibition is associated with activation of the unfolded protein response pathway in myeloma plasma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Therapeutic potential of resveratrol: the in vivo evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Resveratrol downregulates the constitutional activation of nuclear factor-kappaB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

pXBP1(U) encoded in XBP1 pre-mRNA negatively regulates unfolded protein response activator pXBP1(S) in mammalian ER stress response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Resveratrol inhibits myeloma cell growth, prevents osteoclast formation, and promotes osteoblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Resveratrol modifies the expression of apoptotic regulatory proteins and sensitizes non-Hodgkin's lymphoma and multiple myeloma cell lines to paclitaxel-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Impaired feedback regulation of XBP1 as a genetic risk factor for bipolar disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

Proteasome inhibitors disrupt the unfolded protein response in myeloma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

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Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

12 July 2018

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261654

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Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

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XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments

1 reference

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25 September 2018

Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.

1 reference

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Elevated gadd153/chop expression during resveratrol-induced apoptosis in human colon cancer cells

1 reference

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25 September 2018

Multiple myeloma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21723843

12 December 2020

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10.1016/J.EXPHEM.2011.06.007

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6 February 2020

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Europe PubMed Central

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6 February 2020

PubMed publication ID

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6 February 2020

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