Coreceptor gene imprinting governs thymocyte lineage fate. (Q35681609)

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15 January 2020

title

Coreceptor gene imprinting governs thymocyte lineage fate (English)

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6

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author name string

Stanley Adoro

1

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15 January 2020

Thomas McCaughtry

2

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15 January 2020

Batu Erman

3

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15 January 2020

Amala Alag

4

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15 January 2020

François Van Laethem

5

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15 January 2020

Xuguang Tai

7

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15 January 2020

Motoko Kimura

8

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15 January 2020

Lie Wang

9

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15 January 2020

Alex Grinberg

10

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15 January 2020

Masato Kubo

11

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15 January 2020

Remy Bosselut

12

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15 January 2020

Paul Love

13

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15 January 2020

Alfred Singer

14

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language of work or name

English

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publication date

28 October 2011

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15 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22036949 AND SRC:MED&resulttype=core&format=json

15 January 2020

volume

31

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issue

2

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15 January 2020

page(s)

366-377

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Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

15 January 2020

cites work

1 reference

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Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice

12 July 2018

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Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice

12 July 2018

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ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage

12 July 2018

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Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4( ) T cells

12 July 2018

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Development of all CD4 T lineages requires nuclear factor TOX

12 July 2018

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IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival

12 July 2018

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The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

12 July 2018

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The Runx3 distal transcript encodes an additional transcriptional activation domain

12 July 2018

1 reference

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Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes

12 July 2018

1 reference

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The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment

12 July 2018

1 reference

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Functional and molecular analysis of the double-positive stage-specific CD8 enhancer E8III during thymocyte development.

12 July 2018

1 reference

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Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261554

In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8 T cells

12 July 2018

1 reference

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Chromatin and CD4, CD8A and CD8B gene expression during thymic differentiation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261554

Positive and negative selection of T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261554

IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8 memory T cells

12 July 2018

1 reference

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New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3261554

A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box.

12 July 2018

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T cell receptor-induced calcineurin activation regulates T helper type 2 cell development by modifying the interleukin 4 receptor signaling complex

12 July 2018

1 reference

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The regulation of CD4 and CD8 coreceptor gene expression during T cell development

12 July 2018

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An enhancer that directs lineage-specific expression of CD8 in positively selected thymocytes and mature T cells

12 July 2018

1 reference

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Efficient in vivo manipulation of mouse genomic sequences at the zygote stage

12 July 2018

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A lineage-specific transcriptional silencer regulates CD4 gene expression during T lymphocyte development

12 July 2018

1 reference

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Selective development of CD4 T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

12 July 2018

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Activation events during thymic selection

12 July 2018

1 reference

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A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells

12 July 2018

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B6.C-H-2bm12. A new H-2 mutation in the I region in the mouse

12 July 2018

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Multiple developmental stage-specific enhancers regulate CD8 expression in developing thymocytes and in thymus-independent T cells.

12 July 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

Combined deletion of CD8 locus cis-regulatory elements affects initiation but not maintenance of CD8 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

CD4-CD8 lineage commitment is regulated by a silencer element at the ThPOK transcription-factor locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

Modulation of coreceptor transcription during positive selection dictates lineage fate independently of TCR/coreceptor specificity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

Asymmetric signaling requirements for thymocyte commitment to the CD4 versus CD8 T cell lineages: a new perspective on thymic commitment and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038/EMBOJ.2011.388

B cells regulate CD40 ligand-induced IL-12 production in antigen-presenting cells (APC) during T cell/APC interactions

21 January 2018

1 reference

12 December 2020

A Region in the CD8 Gene Locus That Directs Expression to the Mature CD8 T Cell Subset in Transgenic Mice

1 reference

12 December 2020

The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection

1 reference

12 December 2020

Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2011.388

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22036949 AND SRC:MED&resulttype=core&format=json

15 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22036949 AND SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

22036949

1 reference