Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability (Q35661319)

9 August 2017

title

Nuclease-deficient FEN-1 blocks Rad51/BRCA1-mediated repair and causes trinucleotide repeat instability (English)

1 reference

9 August 2017

2

Cynthia T McMurray

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9 August 2017

Craig Spiro

1

1 reference

9 August 2017

language of work or name

English

0 references

publication date

1 September 2003

1 reference

Molecular and Cellular Biology

9 August 2017

published in

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9 August 2017

volume

23

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9 August 2017

issue

17

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9 August 2017

page(s)

6063-6074

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Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

9 August 2017

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Overlapping functions of the Saccharomyces cerevisiae Mre11, Exo1 and Rad27 nucleases in DNA metabolism

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Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity

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The 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instability

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Homologous regions of Fen1 and p21Cip1 compete for binding to the same site on PCNA: a potential mechanism to co-ordinate DNA replication and repair

12 July 2018

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12 July 2018

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12 July 2018

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Different mechanisms underlie DNA instability in Huntington disease and colorectal cancer

12 July 2018

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12 July 2018

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12 July 2018

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Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Defective flap endonuclease 1 activity in mammalian cells is associated with impaired DNA repair and prolonged S phase delay

25 September 2018

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25 September 2018

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25 September 2018

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Trinucleotide expansion in haploid germ cells by gap repair

25 September 2018

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Gender of the embryo contributes to CAG instability in transgenic mice containing a Huntington's disease gene

25 September 2018

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Involvement of flap endonuclease 1 in base excision DNA repair.

25 September 2018

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Sensitivity of a S. cerevisiae RAD27 deletion mutant to DNA-damaging agents and in vivo complementation by the human FEN-1 gene

25 September 2018

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12 December 2020

Human MSH2 binds to trinucleotide repeat DNA structures associated with neurodegenerative diseases

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12 December 2020

Expansion and Length-Dependent Fragility of CTG Repeats in Yeast

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12 December 2020

Multiple pathways of recombination define cellular responses to cisplatin

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12 December 2020

DNA structure determines protein binding and transcriptional efficiency of the proenkephalin cAMP-responsive enhancer

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12 December 2020

Inhibition of flap endonuclease 1 by flap secondary structure and relevance to repeat sequence expansion

1 reference

12 December 2020

A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair

1 reference

12 December 2020

Expansions of CAG Repeat Tracts are Frequent in a Yeast Mutant Defective in Okazaki Fragment Maturation

1 reference

12 December 2020

The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin

1 reference

12 December 2020

GAA instability in Friedreich's Ataxia shares a common, DNA-directed and intraallelic mechanism with other trinucleotide diseases

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12 December 2020

10.1128/MCB.23.17.6063-6074.2003

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

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