Mechanisms of gastrointestinal CD4 T-cell depletion during acute and early human immunodeficiency virus type 1 infection (Q35635026)

9 August 2017

title

Mechanisms of gastrointestinal CD4 T-cell depletion during acute and early human immunodeficiency virus type 1 infection (English)

1 reference

9 August 2017

Peter Lopez

6

0 references

Michael Poles

object named as

Michael A Poles

2

0 references

Anita Shet

object named as

Anita Shet

7

0 references

author name string

Saurabh Mehandru

1

1 reference

9 August 2017

Klara Tenner-Racz

3

1 reference

9 August 2017

Victoria Manuelli

4

1 reference

9 August 2017

Patrick Jean-Pierre

5

1 reference

9 August 2017

Andrea Low

8

1 reference

9 August 2017

Hiroshi Mohri

9

1 reference

9 August 2017

Daniel Boden

10

1 reference

9 August 2017

Paul Racz

11

1 reference

9 August 2017

Martin Markowitz

12

1 reference

9 August 2017

language of work or name

English

0 references

publication date

25 October 2006

1 reference

9 August 2017

1 reference

9 August 2017

volume

81

1 reference

9 August 2017

issue

2

1 reference

9 August 2017

page(s)

599-612

1 reference

Perforin expression in the gastrointestinal mucosa is limited to acute simian immunodeficiency virus infection

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Massive infection and loss of memory CD4 T cells in multiple tissues during acute SIV infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

CD4 T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Primary HIV-1 infection is associated with preferential depletion of CD4 T lymphocytes from effector sites in the gastrointestinal tract

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Severe CD4 T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Persistent immune activation in HIV-1 infection is associated with progression to AIDS.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

The simian immunodeficiency virus deltaNef vaccine, after application to the tonsils of Rhesus macaques, replicates primarily within CD4( ) T cells and elicits a local perforin-positive CD8( ) T-cell response

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

A preponderance of CCR5( ) CXCR4( ) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Impact of HIV-1 infection and highly active antiretroviral therapy on the kinetics of CD4 and CD8 T cell turnover in HIV-infected patients

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

T cell depletion in HIV-1 infection: how CD4 T cells go out of stock

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

New testing strategy to detect early HIV-1 infection for use in incidence estimates and for clinical and prevention purposes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Gastrointestinal tract as a major site of CD4 T cell depletion and viral replication in SIV infection

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

The Unenlarged Lymph Nodes of HIV-1–infected, Asymptomatic Patients with High CD4 T Cell Counts Are Sites for Virus Replication and CD4 T Cell Proliferation. The Impact of Highly Active Antiretroviral Therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Follicular dendritic cells and human immunodeficiency virus infectivity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Human immunodeficiency virus detected in bowel epithelium from patients with gastrointestinal symptoms

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Evidence for susceptibility of intrathymic T-cell precursors and their progeny carrying T-cell antigen receptor phenotypes TCR alpha beta and TCR gamma delta to human immunodeficiency virus infection: a mechanism for CD4 (T4) lymphocyte depleti

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Detection, localization, and quantitation of HIV-associated antigens in intestinal biopsies from patients with HIV

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

T cell differentiation antigens on lymphocytes in the human intestinal lamina propria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Peak SIV replication in resting memory CD4 T cells depletes gut lamina propria CD4 T cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Abundant expression of granzyme A, but not perforin, in granules of CD8 T cells in GALT: implications for immune control of HIV-1 infection

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Low levels of perforin expression in CD8 T lymphocyte granules in lymphoid tissue during acute human immunodeficiency virus type 1 infection

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1797467

Follicular dendritic cell-mediated up-regulation of CXCR4 expression on CD4 T cells and HIV pathogenesis

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17065209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

HIV-1 p24 but not proviral load is increased in the intestinal mucosa compared with the peripheral blood in HIV-infected patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17065209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Perforin is not co-expressed with granzyme A within cytotoxic granules in CD8 T lymphocytes present in lymphoid tissue during chronic HIV infection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17065209

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.01739-06

1 reference

9 August 2017

1 reference

9 August 2017

1 reference