The role of defensins in lung biology and therapy (Q35627809)

9 August 2017

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title

The role of defensins in lung biology and therapy (English)

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9 August 2017

Alexander M Cole

1

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9 August 2017

Alan J Waring

series ordinal

2

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9 August 2017

publication date

1 January 2002

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Treatments in Respiratory Medicine

9 August 2017

published in

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9 August 2017

volume

1

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9 August 2017

issue

4

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9 August 2017

page(s)

249-259

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On a Remarkable Bacteriolytic Element Found in Tissues and Secretions

9 August 2017

cites work

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Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic

21 January 2018

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Human nasal respiratory secretions and host defense

21 January 2018

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Human nasal host defense and sinusitis

21 January 2018

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Activity of abundant antimicrobials of the human airway

21 January 2018

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Calcitermin, a novel antimicrobial peptide isolated from human airway secretions

21 January 2018

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Antimicrobial peptides and proteins in the innate defense of the airway surface

21 January 2018

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Peptide antibiotics and their role in innate immunity

21 January 2018

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Human airway epithelia express a beta-defensin

21 January 2018

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Production of beta-defensins by human airway epithelia

21 January 2018

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Defensins. Natural peptide antibiotics of human neutrophils

21 January 2018

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The peptide antibiotic LL-37/hCAP-18 is expressed in epithelia of the human lung where it has broad antimicrobial activity at the airway surface

21 January 2018

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Epithelial antimicrobial peptides in host defense against infection

21 January 2018

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Killing of gram-negative bacteria by lactoferrin and lysozyme

21 January 2018

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Pathophysiology of rhinitis. Lactoferrin and lysozyme in nasal secretions

21 January 2018

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IMMUNOLOGY:Enhanced: Defensins and Host Defense

21 January 2018

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Paneth cell defensins and innate immunity of the small bowel

21 January 2018

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Evolutionary diversification of the mammalian defensins

21 January 2018

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Defensins in the urinary tract and other tissues

21 January 2018

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Defensins of vertebrate animals

21 January 2018

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Isolation and characterization of human defensin cDNA clones

21 January 2018

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Primary structures of three human neutrophil defensins

21 January 2018

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Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel

21 January 2018

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Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis

21 January 2018

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Localization of expression of human beta defensin-1 in the pancreas and kidney

21 January 2018

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hBD-1: a novel beta-defensin from human plasma

21 January 2018

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Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells

21 January 2018

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Beta-defensin expression in human mammary gland epithelia

21 January 2018

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Abundant human beta-defensin-1 expression in milk and mammary gland epithelium

21 January 2018

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A peptide antibiotic from human skin

21 January 2018

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Mapping of the Gene Encoding Human β-Defensin-2 (DEFB2) to Chromosome Region 8p22–p23.1

21 January 2018

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Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction

21 January 2018

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Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity

21 January 2018

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Antimicrobial peptides as mediators of epithelial host defense

21 January 2018

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Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization

21 January 2018

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The NMR structure of human beta-defensin-2 reveals a novel alpha-helical segment

21 January 2018

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The structure of human beta-defensin-1: new insights into structural properties of beta-defensins

21 January 2018

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The structure of human beta-defensin-2 shows evidence of higher order oligomerization

21 January 2018

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Antimicrobial peptides of multicellular organisms

21 January 2018

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PhoP-PhoQ activates transcription of pmrAB, encoding a two-component regulatory system involved in Salmonella typhimurium antimicrobial peptide resistance

21 January 2018

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Genetic and functional analysis of a PmrA-PmrB-regulated locus necessary for lipopolysaccharide modification, antimicrobial peptide resistance, and oral virulence of Salmonella enterica serovar typhimurium

21 January 2018

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Staphylococcus aureus resistance to human defensins and evasion of neutrophil killing via the novel virulence factor MprF is based on modification of membrane lipids with l-lysine

21 January 2018

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Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia

21 January 2018

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Anti-Candida activity of murine bronchoalveolar lavage fluid.

21 January 2018

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21 January 2018

Human beta-defensin-2

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Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation

21 January 2018

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Monocyte-chemotactic activity of defensins from human neutrophils

21 January 2018

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Identification of defensin-1, defensin-2, and CAP37/azurocidin as T-cell chemoattractant proteins released from interleukin-8-stimulated neutrophils

21 January 2018

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Beta-defensins: linking innate and adaptive immunity through dendritic and T cell CCR6

21 January 2018

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NMR solution structure of murine CCL20/MIP-3alpha, a chemokine that specifically chemoattracts immature dendritic cells and lymphocytes through its highly specific interaction with the beta-chemokine receptor CCR6

21 January 2018

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Cutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity

21 January 2018

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The CXC chemokines gamma interferon (IFN-gamma)-inducible protein 10 and monokine induced by IFN-gamma are released during severe melioidosis

21 January 2018

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Defensin Modulates Tissue-type Plasminogen Activator and Plasminogen Binding to Fibrin and Endothelial Cells

21 January 2018

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Animal antimicrobial peptides: an overview

21 January 2018

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Neutrophil antibacterial peptides, multifunctional effector molecules in the mammalian immune system

21 January 2018

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Human neutrophil defensin and serpins form complexes and inactivate each other

21 January 2018

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Activated alpha 2-macroglobulin is a principal defensin-binding protein

21 January 2018

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Identification of defensin binding to C1 complement

21 January 2018

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Human beta defensin is absent in burn blister fluid

21 January 2018

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Expression and characterization of the cystic fibrosis transmembrane conductance regulator.

21 January 2018

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Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid.

21 January 2018

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Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects

21 January 2018

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Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease

21 January 2018

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Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and "specific" granule deficiency

21 January 2018

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Selective defect in myeloid cell lactoferrin gene expression in neutrophil specific granule deficiency

21 January 2018

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Lactoferrin and lysozyme deficiency in airway secretions: Association with the development of bronchopulmonary dysplasia

21 January 2018

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Innate antimicrobial peptide protects the skin from invasive bacterial infection

21 January 2018

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Processing site and gene structure for the murine antimicrobial peptide CRAMP.

21 January 2018

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Bactenecins, defense polypeptides of bovine neutrophils, are generated from precursor molecules stored in the large granules

21 January 2018

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Proteolytic cleavage by neutrophil elastase converts inactive storage proforms to antibacterial bactenecins

21 January 2018

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Human cathelicidin, hCAP-18, is processed to the antimicrobial peptide LL-37 by extracellular cleavage with proteinase 3

21 January 2018

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Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins

21 January 2018

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A cDNA derived from pig bone marrow cells predicts a sequence identical to the intestinal antibacterial peptide PR-39.

21 January 2018

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A novel cDNA sequence encoding a pig leukocyte antimicrobial peptide with a cathelin-like pro-sequence

21 January 2018

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Identification of a new member of the protegrin family by cDNA cloning

21 January 2018

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Prophenin-1, an exceptionally proline-rich antimicrobial peptide from porcine leukocytes.

21 January 2018

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Molecular cloning and identification of a novel porcine cathelin-like antibacterial peptide precursor

21 January 2018

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PMAP-37, a novel antibacterial peptide from pig myeloid cells. cDNA cloning, chemical synthesis and activity.

21 January 2018

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Inhibition of neutrophil elastase prevents cathelicidin activation and impairs clearance of bacteria from wounds

21 January 2018

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Regulation of intestinal alpha-defensin activation by the metalloproteinase matrilysin in innate host defense

21 January 2018

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Matrilysin expression and function in airway epithelium

21 January 2018

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Host defence (cationic) peptides: what is their future clinical potential?

21 January 2018

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Methods and strategies of peptide ligation

21 January 2018

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Human beta-defensin-1: an antimicrobial peptide of urogenital tissues

21 January 2018

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Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes

21 January 2018

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Three-dimensional structure of RTD-1, a cyclic antimicrobial defensin from Rhesus macaque leukocytes

21 January 2018

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Oligomerization of protegrin‐1 in the presence of DPC micelles. A proton high‐resolution NMR study

21 January 2018

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A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins

21 January 2018

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Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1.

21 January 2018

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Membrane Thinning Effect of the β-Sheet Antimicrobial Protegrin†

21 January 2018

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Glandular secretion of lactoferrin in a patient with neutrophil lactoferrin deficiency

21 January 2018

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Group II Phospholipase A2in Nasal Fluid, Mucosa and Paranasal Sinuses

21 January 2018

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21 January 2018

Identifiers

DOI

10.1007/BF03256616

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9 August 2017

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