Rational identification of an optimal antibody mixture for targeting the epidermal growth factor receptor (Q35624032)

9 August 2017

title

Rational identification of an optimal antibody mixture for targeting the epidermal growth factor receptor (English)

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9 August 2017

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Mikkel Wandahl Pedersen

11

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Lucilla Steinaa

object named as

Lucilla Steinaa

2

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author name string

Klaus Koefoed

1

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9 August 2017

Josefine Nielsen Søderberg

3

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9 August 2017

Ida Kjær

4

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9 August 2017

Helle Jane Jacobsen

5

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9 August 2017

Per-Johan Meijer

6

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9 August 2017

John Sørensen Haurum

7

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9 August 2017

Allan Jensen

8

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9 August 2017

Michael Kragh

9

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9 August 2017

Peter Sejer Andersen

10

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9 August 2017

publication date

1 November 2011

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9 August 2017

published in

Monoclonal Antibodies

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9 August 2017

volume

3

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9 August 2017

issue

6

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9 August 2017

page(s)

584-595

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Primary resistance to cetuximab in a panel of patient-derived tumour xenograft models: activation of MET as one mechanism for drug resistance

9 August 2017

cites work

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IgG isotype, glycosylation, and EGFR expression determine the induction of antibody-dependent cellular cytotoxicity in vitro by cetuximab

12 July 2018

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Sym004: a novel synergistic anti-epidermal growth factor receptor antibody mixture with superior anticancer efficacy.

12 July 2018

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Crosstalk between epidermal growth factor receptor- and insulin-like growth factor-1 receptor signaling: implications for cancer therapy.

12 July 2018

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12 July 2018

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Persistent elimination of ErbB-2/HER2-overexpressing tumors using combinations of monoclonal antibodies: relevance of receptor endocytosis

12 July 2018

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Establishment and characterization of a model of acquired resistance to epidermal growth factor receptor targeting agents in human cancer cells.

12 July 2018

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Interaction of antibodies with ErbB receptor extracellular regions

12 July 2018

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12 July 2018

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Epidermal growth factor receptor targeting in cancer

12 July 2018

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Isolation of human antibody repertoires with preservation of the natural heavy and light chain pairing

12 July 2018

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Functional effects of glycosylation at Asn-579 of the epidermal growth factor receptor

12 July 2018

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12 July 2018

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Domain-level antibody epitope mapping through yeast surface display of epidermal growth factor receptor fragments

12 July 2018

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EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

12 July 2018

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Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

12 July 2018

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Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha

12 July 2018

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The epidermal growth factor receptor: from mutant oncogene in nonhuman cancers to therapeutic target in human neoplasia

12 July 2018

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12 July 2018

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Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis.

12 July 2018

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12 July 2018

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12 July 2018

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Deletion-mutant epidermal growth factor receptor in human gliomas: Effect of type II mutation on receptor function

12 July 2018

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Structural alterations of the epidermal growth factor receptor gene in human gliomas

12 July 2018

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Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies

12 July 2018

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Epidermal growth factor receptor (EGFR) antibody-induced antibody-dependent cellular cytotoxicity plays a prominent role in inhibiting tumorigenesis, even of tumor cells insensitive to EGFR signaling inhibition.

12 July 2018

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Human antibody repertoires.

25 September 2018

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Differential response to gefitinib of cells expressing normal EGFR and the mutant EGFRvIII.

25 September 2018

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Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity.

25 September 2018

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Structural basis for inhibition of the epidermal growth factor receptor by cetuximab

25 September 2018

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Complement-Dependent Tumor Cell Lysis Triggered by Combinations of Epidermal Growth Factor Receptor Antibodies

25 September 2018

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Crossref

https://api.crossref.org/works/10.4161/MABS.3.6.17955

A pan-HER approach for cancer therapy: background, current status and future development

21 January 2018

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12 December 2020

Overexpression of epidermal growth factor and hepatocyte growth factor receptors in a proportion of gastrinomas correlates with aggressive growth and lower curability

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12 December 2020

Enhancement in antigen binding by a combination of synergy and antibody capture

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12 December 2020

Epidermal growth factor receptor-mediated motility in fibroblasts

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12 December 2020

Identifiers

DOI

10.4161/MABS.3.6.17955

1 reference

9 August 2017

1 reference

9 August 2017

1 reference