Myasthenia gravis. CD4 T epitopes on the embryonic gamma subunit of human muscle acetylcholine receptor (Q35607371)

9 August 2017

title

Myasthenia gravis. CD4 T epitopes on the embryonic gamma subunit of human muscle acetylcholine receptor (English)

1 reference

9 August 2017

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1 reference

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20 September 2022

1

M. P. Protti

1 reference

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20 September 2022

4

L. Moiola

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20 September 2022

author name string

A. A. Manfredi

2

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20 September 2022

X. D. Wu

3

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20 September 2022

M. W. Dalton

5

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20 September 2022

J. F. Howard

6

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20 September 2022

B. M. Conti-Tronconi

7

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20 September 2022

language of work or name

English

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publication date

1 October 1992

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full work available at URL

9 August 2017

https://europepmc.org/articles/PMC443203

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:1383275

https://europepmc.org/articles/PMC443203?pdf=render

20 September 2022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:1383275

Journal of Clinical Investigation

20 September 2022

published in

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9 August 2017

volume

90

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9 August 2017

issue

4

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9 August 2017

page(s)

1558-1567

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A histologic reappraisal of the thymus in myasthenia gravis. A correlative study of thymic pathology and response to thymectomy

9 August 2017

cites work

1 reference

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Cloning and sequence analysis of human genomic DNA encoding gamma subunit precursor of muscle acetylcholine receptor

12 July 2018

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Differential regulation of muscle acetylcholine receptor gamma- and epsilon-subunit mRNAs

12 July 2018

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Myasthenia gravis: stimulation of antireceptor autoantibodies by autoreactive T cell lines

12 July 2018

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Immunological evidence for a change in subunits of the acetylcholine receptor in developing and denervated rat muscle

12 July 2018

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Epstein-Barr virus-transformed B cells can present acetylcholine receptor to autologous autoreactive T cells

12 July 2018

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Human T-helper lymphocytes in myasthenia gravis recognize the nicotinic receptor alpha subunit

12 July 2018

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Myasthenic serum selectively blocks acetylcholine receptors with long channel open times at developing rat endplates

12 July 2018

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Structural analysis of peptides capable of binding to more than one Ia antigen

12 July 2018

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12 July 2018

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12 July 2018

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Characterization of a naturally processed MHC class II-restricted T-cell determinant of hen egg lysozyme

12 July 2018

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12 July 2018

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A 16-amino acid peptide of respiratory syncytial virus 1A protein contains two overlapping T cell-stimulating sites distinguishable by class II MHC restriction elements

12 July 2018

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12 July 2018

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HLA class II typing by restriction fragment length polymorphism (RFLP) in unrelated bone marrow transplant patients.

12 July 2018

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A pentapeptide as minimal antigenic determinant for MHC class I-restricted T lymphocytes.

12 July 2018

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Involvement of distinct murine T-cell receptors in the autoimmune encephalitogenic response to nested epitopes of myelin basic protein

12 July 2018

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A juxta-membrane epitope on the human acetylcholine receptor recognized by T cells in myasthenia gravis

12 July 2018

1 reference

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A suppressor T-lymphocyte cell line for autoimmune encephalomyelitis

12 July 2018

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The structure of T-cell epitopes

12 July 2018

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Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

12 July 2018

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12 July 2018

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General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids

12 July 2018

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Immunological heterogeneity of autoreactive T lymphocytes against the nicotinic acetylcholine receptor in myasthenic patients

12 July 2018

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12 July 2018

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Immunodominant regions for T helper-cell sensitization on the human nicotinic receptor alpha subunit in myasthenia gravis

12 July 2018

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Does the presence of self-reactive T cells indicate the breakdown of tolerance?

12 July 2018

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Use of synthetic peptides to establish anti-human acetylcholine receptor CD4 cell lines from myasthenia gravis patients.

12 July 2018

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CD4 T cell response to the human acetylcholine receptor alpha subunit in myasthenia gravis. A study with synthetic peptides.

12 July 2018

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Efficient processing of an antigenic sequence for presentation by MHC class I molecules depends on its neighboring residues in the protein

12 July 2018

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Identification of naturally processed viral nonapeptides allows their quantification in infected cells and suggests an allele-specific T cell epitope forecast

12 July 2018

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Many peptide fragments of alien antigens are homologous with host proteins, thus canalizing T-cell responses

12 July 2018

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Myasthenia Gravis: Prototype of the Antireceptor Autoimmune Diseases

12 July 2018

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Myasthenia gravis. T epitopes on the delta subunit of human muscle acetylcholine receptor

12 July 2018

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A myelin basic protein peptide is recognized by cytotoxic T cells in the context of four HLA-DR types associated with multiple sclerosis

12 July 2018

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12 July 2018

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Isolation of an endogenously processed immunodominant viral peptide from the class I H–2Kb molecule

12 July 2018

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T cells in myasthenia gravis specific for embryonic acetylcholine receptor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443203

Sequence analysis of peptides bound to MHC class II molecules

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=443203

Experimental myasthenia in Balb/c mice immunized with rat acetylcholine receptor from rat denervated muscle

12 July 2018

1 reference

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Antibodies from patients with myasthenia gravis recognize determinants unique to extrajunctional acetylcholine receptors

12 July 2018

1 reference

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The major intrinsic protein (MIP) of the bovine lens fiber membrane: Characterization and structure based on cDNA cloning

12 July 2018

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A malaria T-cell epitope recognized in association with most mouse and human MHC class II molecules

25 September 2018

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Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals

25 September 2018

1 reference

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Adult thymus expresses an embryonic nicotinic acetylcholine receptor-like protein

15 November 2018

1 reference

12 December 2020

Thymectomy as primary therapy in myasthenia gravis

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12 December 2020

Molecular mimicry and autoimmune disease

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12 December 2020

Autoimmune human T lymphocytes specific for acetylcholine receptor

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12 December 2020

Thymic myogenesis, T-lymphocytes and the pathogenesis of myasthenia gravis

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12 December 2020

Mammalian muscle acetylcholine receptor purification and characterization

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12 December 2020

Myasthenia gravis and myasthenic syndromes

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12 December 2020

Primary structure of gamma subunit precursor of calf-muscle acetylcholine receptor deduced from the cDNA sequence

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12 December 2020

Amino acid analysis by reverse-phase high-performance liquid chromatography: precolumn derivatization with phenylisothiocyanate

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12 December 2020

An assay for antibodies to human acetylcholine receptor in serum from patients with myasthenia gravis

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12 December 2020

CD4 T-epitope repertoire on the human acetylcholine receptor alpha subunit in severe myasthenia gravis: a study with synthetic peptides

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12 December 2020

Experimental myasthenia gravis in congenic mice. Sequence mapping and H-2 restriction of T helper epitopes on the alpha subunits of Torpedo californica and murine acetylcholine receptors

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12 December 2020

Competition between foreign and self proteins in antigen presentation. Ovalbumin can inhibit activation of myelin basic protein-specific T cells

1 reference

12 December 2020

The structure of HLA-B27 reveals nonamer self-peptides bound in an extended conformation

1 reference

12 December 2020

Identification of self peptides bound to purified HLA-B27

1 reference

12 December 2020

Fine specificity of T cell recognition of the same peptide in association with different I-A molecules

1 reference

12 December 2020

Analysis of the interaction of peptide hen egg white lysozyme (34-45) with the I-Ak molecule

1 reference

12 December 2020

1 reference

12 December 2020

Antibodies to acetylcholine receptor and tetanus toxoid: in vitro synthesis by thymic lymphocytes

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12 December 2020

Genetic restriction of autoreactive acetylcholine receptor-specific T lymphocytes in myasthenia gravis

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12 December 2020

Antibody heterogeneity and specificity in myasthenia gravis

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12 December 2020

Identifiers

DOI

10.1172/JCI116024

1 reference

9 August 2017

1 reference

9 August 2017

1 reference