Fatty acids suppress autophagic turnover in β-cells (Q35604849)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708 AND SRC:MED&resulttype=core&format=json

11 February 2020

title

Fatty acids suppress autophagic turnover in β-cells (English)

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11 February 2020

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3

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11 February 2020

author name string

Guy Las

1

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11 February 2020

Sam B Serada

2

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11 February 2020

Gilad Twig

4

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11 February 2020

Orian S Shirihai

5

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11 February 2020

language of work or name

English

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publication date

21 August 2011

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Journal of Biological Chemistry

11 February 2020

published in

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11 February 2020

volume

286

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11 February 2020

issue

49

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11 February 2020

page(s)

42534-42544

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Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells

11 February 2020

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12 July 2018

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Autophagy regulates pancreatic beta cell death in response to Pdx1 deficiency and nutrient deprivation

12 July 2018

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12 July 2018

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Mitochondrial networking protects beta-cells from nutrient-induced apoptosis.

12 July 2018

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Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1.

12 July 2018

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12 July 2018

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Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

12 July 2018

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Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

12 July 2018

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Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

12 July 2018

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Autophagy in the Pathogenesis of Disease

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12 July 2018

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Limited mitochondrial permeabilization is an early manifestation of palmitate-induced lipotoxicity in pancreatic beta-cells

12 July 2018

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12 July 2018

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12 July 2018

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Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy

12 July 2018

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Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy

12 July 2018

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12 July 2018

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Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis

12 July 2018

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12 July 2018

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12 July 2018

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Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells

12 July 2018

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Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

12 July 2018

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12 July 2018

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12 July 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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Prolonged exposure to free fatty acids has cytostatic and pro-apoptotic effects on human pancreatic islets: evidence that beta-cell death is caspase mediated, partially dependent on ceramide pathway, and Bcl-2 regulated.

25 September 2018

1 reference

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25 September 2018

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-Cell Mitochondria Exhibit Membrane Potential Heterogeneity That Can Be Altered by Stimulatory or Toxic Fuel Levels

25 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074/JBC.M111.242412

21 January 2018

Identifiers

DOI

10.1074/JBC.M111.242412

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708 AND SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21859708 AND SRC:MED&resulttype=core&format=json

11 February 2020

PubMed publication ID

21859708

1 reference