Multitasking of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor: beyond cardiovascular diseases (Q35602774)

9 August 2017

1 reference

title

Multitasking of the 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor: beyond cardiovascular diseases (English)

1 reference

9 August 2017

main subject

cardiovascular disease

1 reference

Paolo Calabro

1

1 reference

9 August 2017

Edward T H Yeh

series ordinal

2

1 reference

9 August 2017

publication date

1 January 2004

1 reference

Current Atherosclerosis Reports

9 August 2017

published in

1 reference

9 August 2017

volume

6

1 reference

9 August 2017

issue

1

1 reference

9 August 2017

page(s)

36-41

1 reference

Upregulation of Endothelial Nitric Oxide Synthase by HMG CoA Reductase Inhibitors

9 August 2017

cites work

1 reference

Crossref

https://api.crossref.org/works/10.1007/S11883-004-0114-6

Secretory processing of amyloid precursor protein is inhibited by increase in cellular cholesterol content

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1007/S11883-004-0114-6

Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. West of Scotland Coronary Prevention Study Group

21 January 2018

1 reference

12 December 2020

Regulation of the mevalonate pathway

1 reference

12 December 2020

In vivo regulation of human leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase: increased enzyme protein concentration and catalytic efficiency in human leukemia and lymphoma

1 reference

12 December 2020

Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells

1 reference

12 December 2020

Role of protein modification reactions in programming interactions between ras-related GTPases and cell membranes

1 reference

12 December 2020

Statins and the risk of dementia

1 reference

12 December 2020

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

1 reference

12 December 2020

Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study

1 reference

12 December 2020

Cell cycle-specific effects of lovastatin

1 reference

12 December 2020

Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomised controlled trial. Long-term Intervention with Pravastatin in Ischaemic Disease

1 reference

12 December 2020

Inhibitors of hydroxymethylglutaryl-coenzyme A reductase and risk of fracture among older women

1 reference

12 December 2020

Pharmacodynamics and pharmacokinetics of the HMG-CoA reductase inhibitors. Similarities and differences

1 reference

12 December 2020

The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators

1 reference

12 December 2020

Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide

1 reference

12 December 2020

HMG-CoA reductase inhibitor mevastatin enhances the growth inhibitory effect of butyrate in the colorectal carcinoma cell line Caco-2

1 reference

12 December 2020

Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition

1 reference

12 December 2020

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

1 reference

12 December 2020

Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol

1 reference

12 December 2020

Low cholesterol stimulates the nonamyloidogenic pathway by its effect on the alpha -secretase ADAM 10.

1 reference

12 December 2020

Relation of statin use and bone loss: a prospective population-based cohort study in early postmenopausal women

1 reference

12 December 2020

Increase in the active form of 3-hydroxy-3-methylglutaryl coenzyme A reductase in human hepatocellular carcinoma: possible mechanism for alteration of cholesterol biosynthesis

1 reference

12 December 2020

Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductase

1 reference

12 December 2020

Prevention of Cardiovascular Events and Death with Pravastatin in Patients with Coronary Heart Disease and a Broad Range of Initial Cholesterol Levels

1 reference

12 December 2020

Compactin and simvastatin, but not pravastatin, induce bone morphogenetic protein-2 in human osteosarcoma cells

1 reference

12 December 2020

Importance of mevalonate-derived products in the control of HMG-CoA reductase activity and growth of human lung adenocarcinoma cell line A549.

1 reference

12 December 2020

The cellular functions of small GTP-binding proteins

1 reference

12 December 2020

Lovastatin induction of cyclin-dependent kinase inhibitors in human breast cells occurs in a cell cycle-independent fashion.

1 reference

12 December 2020

Cholesterol decreases secretion of the secreted form of amyloid precursor protein by interfering with glycosylation in the protein secretory pathway

1 reference

12 December 2020

HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients

1 reference

12 December 2020

Stimulation of bone formation in vitro and in rodents by statins

1 reference

12 December 2020

Cholesterol inhibition, cancer, and chemotherapy

1 reference

12 December 2020

HMG-CoA reductase inhibitors: role in normal and malignant cells

1 reference

12 December 2020

Enhanced 3-hydroxy-3-methyl-glutaryl coenzyme A reductase activity in human colorectal cancer not expressing low density lipoprotein receptor

1 reference

12 December 2020

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

1 reference

12 December 2020

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

1 reference

12 December 2020

Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras.

1 reference

12 December 2020

Structural mechanism for statin inhibition of HMG-CoA reductase

1 reference

12 December 2020

Lovastatin mediated G1 arrest in normal and tumor breast cells is through inhibition of CDK2 activity and redistribution of p21 and p27, independent of p53.

1 reference

12 December 2020

Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study

1 reference

12 December 2020

Do statins cause cancer? A meta-analysis of large randomized clinical trials

1 reference

12 December 2020

HMG-CoA reductase inhibitors and the risk of fractures

1 reference

12 December 2020

Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

1 reference

12 December 2020

The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates

1 reference

12 December 2020

Clinically relevant pleiotropic effects of statins: drug properties or effects of profound cholesterol reduction?

1 reference

12 December 2020

Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

1 reference

12 December 2020

Synchronization of tumor and normal cells from G1 to multiple cell cycles by lovastatin

1 reference

12 December 2020

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

1 reference

12 December 2020

Lack of positive correlation between statin use and bone mineral density in Japanese subjects with type 2 diabetes

1 reference

12 December 2020

Increased sensitivity of acute myeloid leukemias to lovastatin-induced apoptosis: A potential therapeutic approach

1 reference

12 December 2020

Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications

1 reference

12 December 2020

Selective inhibition of primary acute myeloid leukaemia cell growth by simvastatin.

1 reference

12 December 2020

Carcinogenicity of lipid-lowering drugs

1 reference

12 December 2020

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

1 reference

12 December 2020

Oral statins and increased bone-mineral density in postmenopausal women

1 reference

12 December 2020

10.1007/S11883-004-0114-6

Identifiers

DOI

1 reference

release_fspyhpav4rbwrbghpijhsnyctq

9 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fspyhpav4rbwrbghpijhsnyctq

24 November 2022

mapped directly with Wikidata item

1 reference