IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis (Q35597423)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

title

IL-10-producing intestinal macrophages prevent excessive antibacterial innate immunity by limiting IL-23 synthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Yun-Cai Liu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Bjoern Peters

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Masako Murai

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

author name string

Petra Krause

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Venetia Morris

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Jason A Greenbaum

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Yoon Park

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Unni Bjoerheden

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Tracy Muffley

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Jr-Wen Shui

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Gisen Kim

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Hilde Cheroutre

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

Mitchell Kronenberg

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

English

0 references

publication date

11 May 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

volume

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

7055

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

describes a project that uses

7 March 2020

limma

1 reference

22 June 2022

https://europepmc.org/article/PMC/4428691

inferred from PubMed Central ID database lookup

cites work

Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Attenuation of intestinal inflammation in interleukin-10-deficient mice infected with Citrobacter rodentium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

TSC1 regulates the balance between effector and regulatory T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

The Citrobacter rodentium mouse model: studying pathogen and host contributions to infectious colitis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

CX(3)CR1( ) macrophages support IL-22 production by innate lymphoid cells during infection with Citrobacter rodentium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

HVEM signalling at mucosal barriers provides host defence against pathogenic bacteria

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

IL-10R polymorphisms are associated with very-early-onset ulcerative colitis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

The regulation of IL-10 production by immune cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

IL-12p40: an inherently agonistic cytokine

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Animal models of inflammatory bowel disease: lessons from enteric infections

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Interleukin-23 drives innate and T cell-mediated intestinal inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Citrobacter rodentium of mice and man.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Bioconductor: open software development for computational biology and bioinformatics

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Human monocytes express CD163, which is upregulated by IL-10 and identical to p155.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Early resistance of interleukin-10 knockout mice to acute systemic candidiasis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

The Orphan Receptor CRF2-4 Is an Essential Subunit of the Interleukin 10 Receptor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

A CD4 T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Effects of in vivo administration of anti-IL-10 monoclonal antibody on the host defence mechanism against murine Salmonella infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Regulated virulence controls the ability of a pathogen to compete with the gut microbiota.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Monocytes/macrophages and/or neutrophils are the target of IL-10 in the LPS endotoxemia model

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Th1/Th17 immune response is induced by mesenteric lymph node dendritic cells in Crohn's disease.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

T cell-specific inactivation of the interleukin 10 gene in mice results in enhanced T cell responses but normal innate responses to lipopolysaccharide or skin irritation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4 regulatory T cells and IL-10.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Prevention of colitis by interleukin 10-transduced T lymphocytes in the SCID mice transfer model

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Interleukin-10-deficient mice develop chronic enterocolitis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Paralysis of Dendritic Cell IL-12 Production by Microbial Products Prevents Infection-Induced Immunopathology

26 September 2018

1 reference

Crossref

Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis

21 January 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

26 September 2018

In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4 T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alpha

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

Interleukin-10 derived from macrophages and/or neutrophils regulates the inflammatory response to LPS but not the response to CpG DNA

26 September 2018

1 reference

Crossref

Commensal microbiota induce LPS hyporesponsiveness in colonic macrophages via the production of IL-10

21 January 2018

1 reference

Crossref

IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428691

IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii

15 November 2018

1 reference

12 December 2020

Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction

1 reference

12 December 2020

Neutralization of IL-10 increases survival in a murine model of Klebsiella pneumonia

1 reference

12 December 2020

Both innate and acquired immunity to Listeria monocytogenes infection are increased in IL-10-deficient mice

1 reference

12 December 2020

Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCOMMS8055

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

25959063

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25959063 AND SRC:MED&resulttype=core&format=json