Talampanel reduces the level of motoneuronal calcium in transgenic mutant SOD1 mice only if applied presymptomatically (Q35595854)

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2 February 2020

title

Talampanel reduces the level of motoneuronal calcium in transgenic mutant SOD1 mice only if applied presymptomatically (English)

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2 February 2020

3

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2 February 2020

author name string

Melinda Paizs

1

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2 February 2020

Massimo Tortarolo

2

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2 February 2020

József I Engelhardt

4

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2 February 2020

László Siklós

5

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2 February 2020

publication date

30 May 2011

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Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders

2 February 2020

published in

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2 February 2020

volume

12

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2 February 2020

issue

5

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2 February 2020

page(s)

340-344

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Clinical trials for neuroprotection in ALS.

2 February 2020

cites work

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Guidelines for preclinical animal research in ALS/MND: A consensus meeting

27 July 2018

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A phase II trial of talampanel in subjects with amyotrophic lateral sclerosis

27 July 2018

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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

27 July 2018

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Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

27 July 2018

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The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis.

27 July 2018

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Intracellular calcium redistribution accompanies changes in total tissue Na , K and water during the first two hours of in vitro incubation of hippocampal slices

27 July 2018

1 reference

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Qualitative enzyme histochemistry and microanalysis reveals changes in ultrastructural distribution of calcium and calcium-activated ATPases after microwave irradiation of the medial habenula

27 July 2018

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Amyotrophic lateral sclerosis is a multifactorial disease

27 July 2018

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Intranuclear microtubules in lung mast cells of guinea pigs in anaphylactic shock

27 July 2018

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Evidence of multisystem disorder in whole-brain map of pathological TDP-43 in amyotrophic lateral sclerosis

27 July 2018

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Amyotrophic lateral sclerosis and excitotoxicity: from pathological mechanism to therapeutic target.

21 January 2018

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The AMPA receptor antagonist NBQX prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis

21 January 2018

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Glutamate AMPA receptors change in motor neurons of SOD1G93A transgenic mice and their inhibition by a noncompetitive antagonist ameliorates the progression of amytrophic lateral sclerosis-like disease

21 January 2018

1 reference

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21 January 2018

1 reference

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Hypoglossal motor neurons display a reduced calcium increase after axotomy in mice with upregulated parvalbumin

21 January 2018

1 reference

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Diazoxide prevents mitochondrial swelling and Ca2 accumulation in CA1 pyramidal cells after cerebral ischemia in newborn pigs

21 January 2018

1 reference

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Sublethal dose of 4-hydroxynonenal reduces intracellular calcium in surviving motor neurons in vivo

21 January 2018

1 reference

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Treatment with lithium carbonate does not improve disease progression in two different strains of SOD1 mutant mice

21 January 2018

1 reference

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Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice.

21 January 2018

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Ultrastructural localization of calcium in the CNS of vertebrates

21 January 2018

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DL-Homocysteic acid application disrupts calcium homeostasis and induces degeneration of spinal motor neurons in vivo

21 January 2018

1 reference

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Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis

21 January 2018

1 reference

12 December 2020

The subcellular distribution of calcium and the effects of calcium-antagonists as evaluated with a combined oxalate-pyroantimonate technique

1 reference

12 December 2020

Morphological and histochemical changes in intercellular junctional complexes in epithelial cells of mouse small intestine upon X-irradiation: changes of ruthenium red permeability and calcium content

1 reference

12 December 2020

A new cytochemical method for the ultrastructural localization of calcium in the central nervous system

1 reference

12 December 2020

Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis

1 reference

12 December 2020

Altered calcium homeostasis and ultrastructure in motoneurons of mice caused by passively transferred anti-motoneuronal IgG

1 reference

12 December 2020

The need for biomarkers in amyotrophic lateral sclerosis drug development

1 reference

12 December 2020

10.3109/17482968.2011.584627

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21623665 AND SRC:MED&resulttype=core&format=json

release_zas2i43lpbdcjc4fighwrcsscy

2 February 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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2 February 2020

PubMed publication ID

21623665

1 reference