The thymic cortical epithelium determines the TCR repertoire of IL-17-producing γδT cells. (Q35595498)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770130 AND SRC:MED&resulttype=core&format=json

2 March 2020

title

The thymic cortical epithelium determines the TCR repertoire of IL-17-producing γδT cells (English)

1 reference

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2 March 2020

1 reference

13

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2 March 2020

author name string

Takeshi Nitta

1

1 reference

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2 March 2020

Ryunosuke Muro

2

1 reference

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2 March 2020

Yukiko Shimizu

3

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2 March 2020

Sachiko Nitta

4

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2 March 2020

Hiroyo Oda

5

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2 March 2020

Yuki Ohte

6

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2 March 2020

Motohito Goto

7

1 reference

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2 March 2020

Rieko Yanobu-Takanashi

8

1 reference

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2 March 2020

Tomoya Narita

9

1 reference

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2 March 2020

Hiroshi Takayanagi

10

1 reference

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2 March 2020

Hisataka Yasuda

11

1 reference

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2 March 2020

Tadashi Okamura

12

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2 March 2020

Harumi Suzuki

14

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2 March 2020

publication date

13 March 2015

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2 March 2020

1 reference

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2 March 2020

volume

16

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2 March 2020

issue

5

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2 March 2020

page(s)

638-653

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Differential developmental requirement and peripheral regulation for dermal Vγ4 and Vγ6T17 cells in health and inflammation

2 March 2020

cites work

1 reference

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Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)

27 July 2018

1 reference

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An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells

27 July 2018

1 reference

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Serial progression of cortical and medullary thymic epithelial microenvironments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Regulations of gene expression in medullary thymic epithelial cells required for preventing the onset of autoimmune diseases

27 July 2018

1 reference

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Functional development of γδ T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Aire-expressing thymic medullary epithelial cells originate from β5t-expressing progenitor cells

27 July 2018

1 reference

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Deficiency in IL-17-committed Vγ4( ) γδ T cells in a spontaneous Sox13-mutant CD45.1( ) congenic mouse substrain provides protection from dermatitis

27 July 2018

1 reference

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A network of high-mobility group box transcription factors programs innate interleukin-17 production

27 July 2018

1 reference

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Murine thymic selection quantified using a unique method to capture deleted T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Six-of-the-best: unique contributions of γδ T cells to immunology

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Generation of both cortical and Aire( ) medullary thymic epithelial compartments from CD205( ) progenitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

The development of T lymphocytes in fetal thymus organ culture

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Interleukin 7 (IL-7) selectively promotes mouse and human IL-17-producing γδ cells.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Thymic epithelial cells: working class heroes for T cell development and repertoire selection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Rorγt innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Rank signaling links the development of invariant γδ T cell progenitors and Aire( ) medullary epithelium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Regenerative capacity of adult cortical thymic epithelial cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Pivotal Role of Dermal IL-17-Producing γδ T Cells in Skin Inflammation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Skint-1 is a highly specific, unique selecting component for epidermal T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress

27 July 2018

1 reference

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Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsets

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

The thymus medulla slowly yields its secrets.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Dissecting beta-ring assembly pathway of the mammalian 20S proteasome.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

The ubiquitin-proteasome system

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Gammadelta T cells: functional plasticity and heterogeneity

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Cathepsin L regulates CD4 T cell selection independently of its effect on invariant chain: a role in the generation of positively selecting peptide ligands

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Analysis of thymic stromal cell populations using flow cytometry

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

NKT cells derive from double-positive thymocytes that are positively selected by CD1d

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Extravascular coagulation and fibrinolysis in murine lung inflammation induced by the mycobacterial cord factor trehalose-6,6'-dimycolate.

27 July 2018

1 reference

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T cell receptor antagonist peptides induce positive selection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Diversity of murine gamma genes and expression in fetal and adult T lymphocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Normal development of mice deficient in beta 2M, MHC class I proteins, and CD8 T cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Mice lacking MHC class II molecules

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

IL-7 produced by thymic epithelial cells plays a major role in the development of thymocytes and TCRγδ intraepithelial lymphocytes

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Thymoproteasome subunit-β5T generates peptide-MHC complexes specialized for positive selection

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

The thymic medulla is required for Foxp3 regulatory but not conventional CD4 thymocyte development

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Differential requirement for RhoH in development of TCRαβ CD8αα IELs and other types of T cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

The natural and the inducible: interleukin (IL)-17-producing γδ T cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Development of interleukin-17-producing γδ T cells is restricted to a functional embryonic wave

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit β5t.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Thymoproteasome shapes immunocompetent repertoire of CD8 T cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Thymus-specific serine protease regulates positive selection of a subset of CD4 thymocytes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Birth of mice from vitrified/warmed 2-cell embryos transported at a cold temperature

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Identification of CD25 gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Skint1, the prototype of a newly identified immunoglobulin superfamily gene cluster, positively selects epidermal gammadelta T cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Regulation of CD8 T cell development by thymus-specific proteasomes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Homing of immature thymocytes to the subcapsular microenvironment within the thymus is not an absolute requirement for T cell development

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

CCR7 signals are essential for cortex-medulla migration of developing thymocytes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Subset-specific, uniform activation among V gamma 6/V delta 1 gamma delta T cells elicited by inflammation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Lymphotoxin-beta receptor mediates NEMO-independent NF-kappaB activation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Defective TCR expression in transgenic mice constructed using cDNA-based α- and β-chain genes under the control of heterologous regulatory elements

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4428049

Pulmonary TCR γδ T cells induce the early inflammation of granuloma formation by a glycolipid trehalose 6,6'-dimycolate (TDM) isolated from Mycobacterium tuberculosis

15 November 2018

1 reference

12 December 2020

Severe defect in thymic development in an insertional mutant mouse model

1 reference

12 December 2020

Checkpoints in the development of thymic cortical epithelial cells

1 reference

12 December 2020

Effects of RANKL on the thymic medulla

1 reference

12 December 2020

Notch-Hes1 pathway is required for the development of IL-17-producing T cells

1 reference

12 December 2020

Hiding under the skin: Interleukin-17-producing γδ T cells go under the skin?

1 reference

12 December 2020

CCR7-mediated migration in the thymus controls γδ T-cell development

1 reference

12 December 2020

MHC class I expression in mice lacking the proteasome subunit LMP-7

1 reference

12 December 2020

Identifiers

DOI

10.15252/EMBR.201540096

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770130 AND SRC:MED&resulttype=core&format=json

2 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25770130 AND SRC:MED&resulttype=core&format=json

2 March 2020

PubMed publication ID

25770130

1 reference