Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel (Q35590205)

9 August 2017

title

Polyunsaturated fatty acid analogs act antiarrhythmically on the cardiac IKs channel (English)

1 reference

9 August 2017

0 references

Johan E Larsson

5

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Malin Silverå Ejneby

Malin Silverå Ejneby

2

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Mark A Skarsfeldt

Mark Alexander Skarsfeldt

4

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Sara I Börjesson

Sara I Liin

1

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Fredrik Elinder

Fredrik Elinder

11

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Nicole Schmitt

Nicole Schmitt

9

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Bo Hjorth Bentzen

Bo Hjorth Bentzen

8

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author name string

Rene Barro-Soria

3

1 reference

9 August 2017

Frida Starck Härlin

6

1 reference

9 August 2017

Teija Parkkari

7

1 reference

9 August 2017

H Peter Larsson

10

1 reference

9 August 2017

language of work or name

English

0 references

publication date

21 April 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

9 August 2017

published in

1 reference

9 August 2017

volume

112

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9 August 2017

issue

18

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9 August 2017

page(s)

5714-5719

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KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps

9 August 2017

cites work

1 reference

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Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

27 July 2018

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Effects of n-3 Polyunsaturated Fatty Acids on Cardiac Ion Channels

27 July 2018

1 reference

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Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels

27 July 2018

1 reference

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Stoichiometry of the KCNQ1 - KCNE1 ion channel complex.

27 July 2018

1 reference

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Electrostatic tuning of cellular excitability

27 July 2018

1 reference

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The acrylamide (S)-2 as a positive and negative modulator of Kv7 channels expressed in Xenopus laevis oocytes

27 July 2018

1 reference

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Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines

27 July 2018

1 reference

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Structure, function, and modification of the voltage sensor in voltage-gated ion channels

27 July 2018

1 reference

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Polyunsaturated fatty acid modulation of voltage-gated ion channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Lipoelectric modification of ion channel voltage gating by polyunsaturated fatty acids

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Desensitization of chemical activation by auxiliary subunits: convergence of molecular determinants critical for augmenting KCNQ1 potassium channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Zinc pyrithione-mediated activation of voltage-gated KCNQ potassium channels rescues epileptogenic mutants

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

KCNE beta subunits determine pH sensitivity of KCNQ1 potassium channels

27 July 2018

1 reference

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Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial

27 July 2018

1 reference

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Membrane effects of the n-3 fish oil fatty acids, which prevent fatal ventricular arrhythmias

27 July 2018

1 reference

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Molecular physiology of cardiac repolarization

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Long QT syndrome in neonates: conduction disorders associated with HERG mutations and sinus bradycardia with KCNQ1 mutations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

The open pore conformation of potassium channels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

MinK subdomains that mediate modulation of and association with KvLQT1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto miocardico

27 July 2018

1 reference

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A Novel Benzodiazepine that Activates Cardiac Slow Delayed Rectifier K Currents

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Fatty acid transport: difficult or easy?

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: diet and reinfarction trial (DART).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane microdomains.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Drug-induced ion channel opening tuned by the voltage sensor charge profile

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Exploration of human, rat, and rabbit embryonic cardiomyocytes suggests K-channel block as a common teratogenic mechanism

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

An electrostatic potassium channel opener targeting the final voltage sensor transition

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Refinement of the binding site and mode of action of the anticonvulsant Retigabine on KCNQ K channels.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Effect of n-3 polyunsaturated fatty acids in patients with chronic heart failure (the GISSI-HF trial): a randomised, double-blind, placebo-controlled trial

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

The acrylamide (S)-1 differentially affects Kv7 (KCNQ) potassium channels

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Modulation of native T-type calcium channels by omega-3 fatty acids

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Effects of free fatty acids on sodium currents in rat dorsal root ganglion neurons

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Prevention of sudden cardiac death by n-3 polyunsaturated fatty acids

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Elevated polyunsaturated fatty acids in blood serum obtained from children on the ketogenic diet

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Modulation of homomeric and heteromeric KCNQ1 channels by external acidification

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Chemistry of ion coordination and hydration revealed by a K channel-Fab complex at 2.0 A resolution

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Sinus node function and ventricular repolarization during exercise stress test in long QT syndrome patients with KvLQT1 and HERG potassium channel defects.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Effect of supplementation with different doses of DHA on the levels of circulating DHA as non-esterified fatty acid in subjects of Asian Indian background

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Transmembrane movement of the shaker K channel S4.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4426425

Gated access to the pore of a voltage-dependent K channel

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25901329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Prevention of ischemia‐induced cardiac Sudden death by n−3 polyunsaturated fatty acids in dogs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25901329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Incorporated sarcolemmal fish oil fatty acids shorten pig ventricular action potentials

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25901329

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1503488112

1 reference

9 August 2017

0 references

1 reference

9 August 2017

1 reference