Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells. (Q35589735)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

review article

1 reference

title

Estrogen and its metabolites are carcinogenic agents in human breast epithelial cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

author name string

Jose Russo

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

M Hasan Lareef

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

Shanchun Guo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

Irma H Russo

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

publication date

1 October 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

The Journal of Steroid Biochemistry and Molecular Biology

21 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

volume

87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

page(s)

1-25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

cites work

Cancer statistics, 1999.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogens, progestogens, normal breast cell proliferation, and breast cancer risk

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Reproductive factors and breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Endogenous hormones and breast cancer risk

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Three stages of responsiveness to hormones in the mammary cell

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogens regulate production of specific growth factors in hormone-dependent human breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Menopausal Estrogen Replacement Therapy and Breast Cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Endogenous estrogens and breast cancer risk: the case for prospective cohort studies

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Oral contraceptive use and malignancies of the genital tract. Results from the Royal College of General Practitioners' Oral Contraception Study

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen-regulated non-reproductive behaviors and breast cancer risk: Animal models and human studies

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Medical hypothesis: bifunctional genetic-hormonal pathways to breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

An updated review of environmental estrogen and androgen mimics and antagonists.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Predictors of breast cancer in women recalled following screening

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen Receptor Null Mice: What Have We Learned and Where Will They Lead Us?

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Molecular mechanisms of action of steroid/thyroid receptor superfamily members

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Dynamics of steroid hormone receptor action

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

ER beta: identification and characterization of a novel human estrogen receptor

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Differential Ligand Activation of Estrogen Receptors ERα and ERβ at AP1 Sites

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Isolation and characterization of an estrogen binding protein which may integrate the plethora of estrogenic actions in non-reproductive organs

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

A novel human estrogen receptor beta: identification and functional analysis of additional N-terminal amino acids

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

1 reference

7 January 2021

Structure, regulation and role of 3 beta-hydroxysteroid dehydrogenase, 17 beta-hydroxysteroid dehydrogenase and aromatase enzymes in the formation of sex steroids in classical and peripheral intracrine tissues

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrone sulfate-sulfatase and 17 beta-hydroxysteroid dehydrogenase activities: a hypothesis for their role in the evolution of human breast cancer from hormone-dependence to hormone-independence

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Breast cancer and the role of cytokines in regulating estrogen synthesis: an emerging hypothesis

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Macrophages, estrogen and the microenvironment of breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The importance of local synthesis of estrogen within the breast

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Aromatase expression and its localization in human breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Age Changes and Sex Differences in Serum Dehydroepiandrosterone Sulfate Concentrations throughout Adulthood

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Distribution of 17 beta-hydroxysteroid dehydrogenase gene expression and activity in rat and human tissues

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Characteristics of human types 1, 2 and 3 17 beta-hydroxysteroid dehydrogenase activities: oxidation/reduction and inhibition

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Relationship between tumour aromatase activity, tumour characteristics and response to therapy

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Role of hormones in mammary cancer initiation and progression

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Influence of age and parity on the development of the human breast

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Pattern of distribution of cells positive for estrogen receptor alpha and progesterone receptor in relation to proliferating cells in the mammary gland

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

17 beta-Estradiol-mediated growth inhibition of MDA-MB-468 cells stably transfected with the estrogen receptor: cell cycle effects

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Hormone receptors and cathepsin D levels in human breast epithelial cells transformed by chemical carcinogens and c-Ha-ras transfection

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen Metabolism and Excretion in Oriental and Caucasian Women

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Polarity and nucleation of microtubules in polarized epithelial cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Regulation and regulatory activities of centrosomes

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The mitotic machinery as a source of genetic instability in cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Centrosome hypertrophy in human breast tumors: Implications for genomic stability and cell polarity

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Genetic instabilities in human cancers

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Evidence that error-prone DNA repair converts dibenzo[a,l]pyrene-induced depurinating lesions into mutations: formation, clonal proliferation and regression of initiated cells carrying H-ras oncogene mutations in early preneoplasia

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen receptor status and dietary intakes in breast cancer patients

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Hormone receptors and breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: down-regulation of ER-beta in neoplastic tissues

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The pathophysiological role of estrogen receptor variants in human breast cancer.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Conversion of estrone to 2- and 4-hydroxyestrone by hamster kidney and liver microsomes: implications for the mechanism of estrogen-induced carcinogenesis.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Importance of A-ring substitution of estrogens for the physiology and pharmacology of reproduction

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Upregulation of estradiol C16 alpha-hydroxylation in human breast tissue: a potential biomarker of breast cancer risk.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The metabolism of 17 beta-estradiol by lactoperoxidase: a possible source of oxidative stress in breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The etiology of breast cancer. Characteristic alteration in hydroxyl radical-induced DNA base lesions during oncogenesis with potential for evaluating incidence risk

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Molecular origin of cancer: Catechol estrogen-3,4-quinones as endogenous tumor initiators

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen carcinogenesis in hamster tissues: a critical review

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Is estradiol a genotoxic mutagenic carcinogen?

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogens as endogenous genotoxic agents--DNA adducts and mutations

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Involvement of genotoxic effects in the initiation of estrogen-induced cellular transformation: studies using Syrian hamster embryo cells treated with 17beta-estradiol and eight of its metabolites

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Carcinogenicity of estrogens in human breast epithelial cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Induction by estrogens of methotrexate resistance in MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Estrogen-induced microsatellite DNA alterations are associated with Syrian hamster kidney tumorigenesis

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Molecular genetic analysis of clear cell adenocarcinomas of the vagina and cervix associated and unassociated with diethylstilbestrol exposure in utero

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Microsatellite instability correlates with negative expression of estrogen and progesterone receptors in sporadic breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Detection of microsatellite alterations in nipple discharge accompanied by breast cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Loss of heterozygosity and microsatellite instability in ductal carcinoma in situ of the breast.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Frequency of microsatellite instability inBreast cancer determined by high-resolution fluorescent microsatellite analysis

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The approach to understanding aromatic hydrocarbon carcinogenesis. The central role of radical cations in metabolic activation

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Relating aromatic hydrocarbon-induced DNA adducts and c-H-ras mutations in mouse skin papillomas: the role of apurinic sites

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Carcinogenicity of catechol estrogens in Syrian hamsters

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Detection of dibenzo[a,l]pyrene-induced H-ras codon 61 mutant genes in preneoplastic SENCAR mouse skin using a new PCR-RFLP method.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Aromatase within the breast

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Tissue-specific synthesis and oxidative metabolism of estrogens.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Chemically induced aneuploidy in mammalian cells: mechanisms and biological significance in cancer

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Aneuploidy and Consistent Structural Chromosome Changes Associated with Transformation of Syrian Hamster Embryo Cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Clustering of aberrations to specific chromosomes in human neoplasms. IV. A survey of 1,871 cases

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Effects of estrogen and estrogen-progestin on mammographic parenchymal density. Postmenopausal Estrogen/Progestin Interventions (PEPI) Investigators

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Menopausal estrogen and estrogen-progestin replacement therapy and breast cancer risk

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Effect of hormone replacement therapy on breast cancer risk: estrogen versus estrogen plus progestin

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Abnormal centrosome amplification in the absence of p53.

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Altered centrosome structure is associated with abnormal mitoses in human breast tumors

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Chromosome abnormalities in benign hyperproliferative disorders of epithelial and stromal breast tissue

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

New gene forges link between fragile site and many cancers

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Telomerase repressor sequences on chromosome 3 and induction of permanent growth arrest in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

A highly polymorphic probe on 11p15.5: L22.5.2 (D11S774).

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Mapping of the gene encoding the integrin-linked kinase, ILK, to human chromosome 11p15.5-p15.4

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Regulation of integrin function by the urokinase receptor

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Transformation of human breast epithelial cells by chemical carcinogens

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

17Beta-estradiol is carcinogenic in human breast epithelial cells

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Microsatellite instability during the immortalization and transformation of human breast epithelial cells in vitro

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

CENP-E is a putative kinetochore motor that accumulates just before mitosis

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Sporadic breast cancer in young women: prevalence of loss of heterozygosity at p53, BRCA1 and BRCA2

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Genetic pathways in the evolution of breast ductal carcinoma in situ

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Loss of heterozygosity on chromosome 17q in epithelial ovarian tumors: association with carcinomas with serous differentiation

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Four regions of allelic imbalance on 17q12-qter associated with high-grade breast tumors

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Transformation of human breast epithelial cells by c-Ha-ras oncogene

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

Generation and reproductive phenotypes of mice lacking estrogen receptor beta

1 reference

https://api.crossref.org/works/10.1016/S0960-0760(03)00390-X

7 January 2021

10.1016/S0960-0760(03)00390-X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14630087 AND SRC:MED&resulttype=core&format=json

21 December 2019

1 reference