Current status and prospects for gene and cell therapeutics for type 1 diabetes mellitus (Q35583901)

9 August 2017

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title

Current status and prospects for gene and cell therapeutics for type 1 diabetes mellitus (English)

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islet cell transplantation

9 August 2017

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:14618022

2 April 2024

1 reference

10.1023/A:1027306213563

https://api.crossref.org/works/10.1023/A:1027306213563

2 April 2024

author name string

Nick Giannoukakis

series ordinal

1

1 reference

9 August 2017

Massimo Trucco

series ordinal

2

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9 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14618022

2 April 2024

publication date

1 December 2003

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Reviews in Endocrine and Metabolic Disorders

9 August 2017

published in

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9 August 2017

volume

4

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9 August 2017

issue

4

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9 August 2017

page(s)

369-380

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Overexpression of catalase provides partial protection to transgenic mouse beta cells

9 August 2017

cites work

1 reference

12 December 2020

Regulation of immune responses by natural killer T cells

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12 December 2020

Effect of reg protein on rat pancreatic ductal cells

1 reference

12 December 2020

Prior streptozotocin treatment does not inhibit pancreas regeneration after 90% pancreatectomy in rats

1 reference

12 December 2020

Regulation of proliferation and differentiation of human fetal pancreatic islet cells by extracellular matrix, hepatocyte growth factor, and cell-cell contact

1 reference

12 December 2020

Protection against autoimmune diabetes by induction of mixed bone marrow chimerism

1 reference

12 December 2020

Insulin promoter factor-1 controls several aspects of beta-cell identity

1 reference

12 December 2020

In vivo maturation and growth potential of human fetal pancreases: fresh versus cultured tissue

1 reference

12 December 2020

Suppression of autoimmune diabetes by viral IL-10 gene transfer

1 reference

12 December 2020

Natural resistance of human beta cells toward nitric oxide is mediated by heat shock protein 70.

1 reference

12 December 2020

Prevention of diabetes in nonobese diabetic mice by dendritic cell transfer

1 reference

12 December 2020

Cytokines and nitric oxide in islet inflammation and diabetes

1 reference

12 December 2020

Dendritic cells and tolerance induction.

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12 December 2020

IL-1 produced and released endogenously within human islets inhibits beta cell function

1 reference

12 December 2020

Clinical results after islet transplantation

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12 December 2020

In vitro cultivation of human islets from expanded ductal tissue

1 reference

12 December 2020

Flexible management of enzymatic digestion improves human islet isolation outcome from sub-optimal donor pancreata

1 reference

12 December 2020

Overexpression of hexokinase I in isolated islets of Langerhans via recombinant adenovirus. Enhancement of glucose metabolism and insulin secretion at basal but not stimulatory glucose levels

1 reference

12 December 2020

Attenuation of FGF signalling in mouse β-cells leads to diabetes

1 reference

12 December 2020

Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase

1 reference

12 December 2020

Adenoviral delivery of CTLA4Ig into myeloid dendritic cells promotes their in vitro tolerogenicity and survival in allogeneic recipients

1 reference

12 December 2020

Mixed allogeneic chimerism achieved by lethal and nonlethal conditioning approaches induces donor-specific tolerance to simultaneous islet allografts

1 reference

12 December 2020

Insulin staining of ES cell progeny from insulin uptake.

1 reference

12 December 2020

Human therapeutic cloning.

1 reference

12 December 2020

Adenovirus-mediated catalase gene transfer reduces oxidant stress in human, porcine and rat pancreatic islets

1 reference

12 December 2020

Molecular correlates of primate nuclear transfer failures

1 reference

12 December 2020

Isolation of the regulatory regions and genomic organization of the porcine alpha1,3-galactosyltransferase gene

1 reference

12 December 2020

Development of pancreatic islets (review).

1 reference

12 December 2020

Production of alpha 1,3-galactosyltransferase-deficient pigs

1 reference

12 December 2020

Transcription Factors Contributing to the Pancreatic β-Cell Phenotype

1 reference

12 December 2020

Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol

1 reference

12 December 2020

Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets.

1 reference

12 December 2020

Protection against autoimmune diabetes in mixed bone marrow chimeras: mechanisms involved

1 reference

12 December 2020

Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I.

1 reference

12 December 2020

Oral Administration of the Immunodominant B-chain of Insulin Reduces Diabetes in a Co-transfer Model of Diabetes in the NOD Mouse and is Associated with a Switch from Th1 to Th2 Cytokines

1 reference

12 December 2020

Induction of mixed bone marrow chimerism as potential therapy for autoimmune (type I) diabetes: experience in the NOD model

1 reference

12 December 2020

Transduction of dendritic cell progenitors with a retroviral vector encoding viral interleukin-10 and enhanced green fluorescent protein allows purification of potentially tolerogenic antigen-presenting cells

1 reference

12 December 2020

Recovery of function and mass of endogenous beta-cells in streptozotocin-induced diabetic rats treated with islet transplantation

1 reference

12 December 2020

Functional analysis of a conditionally transformed pancreatic beta-cell line

1 reference

12 December 2020

Therapeutic cloning: needs and prospects

1 reference

12 December 2020

IL-10 and TGF-beta gene transfer to rodent islets: effect on xenogeneic islet graft survival in naive and B-cell-deficient mice

1 reference

12 December 2020

Hepatocyte growth factor/scatter factor has insulinotropic activity in human fetal pancreatic cells

1 reference

12 December 2020

Characterization of a class of cationic peptides able to facilitate efficient protein transduction in vitro and in vivo

1 reference

12 December 2020

Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs

1 reference

12 December 2020

Progression to insulin-requiring diabetes in seronegative prediabetic subjects: the role of two HLA-DQ high-risk haplotypes

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12 December 2020

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

1 reference

12 December 2020

Characteristics of rat pancreatic regenerating protein

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12 December 2020

Protection of human islets from the effects of interleukin-1beta by adenoviral gene transfer of an Ikappa B repressor

1 reference

12 December 2020

Efficient transduction of nondividing cells by optimized feline immunodeficiency virus vectors.

1 reference

12 December 2020

Prevention of autoimmune diabetes by immunogene therapy using recombinant vaccinia virus expressing glutamic acid decarboxylase.

1 reference

12 December 2020

A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

1 reference

12 December 2020

Inhibition of protein kinase C delta protects rat INS-1 cells against interleukin-1beta and streptozotocin-induced apoptosis

1 reference

12 December 2020

Therapeutic controversy: prevention and treatment of diabetes in children

1 reference

12 December 2020

Efficient transduction of nondividing human cells by feline immunodeficiency virus lentiviral vectors

1 reference

12 December 2020

Cloning and sequencing of the pancreatic islet neogenesis associated protein (INGAP) gene and its expression in islet neogenesis in hamsters

1 reference

12 December 2020

Probability of remission in individual in early adult insulin dependent diabetic patients. Results from the Cyclosporine Diabetes French Study Group

1 reference

12 December 2020

The intraislet macrophage and type I diabetes.

1 reference

12 December 2020

Potential role of resident islet macrophage activation in the initiation of autoimmune diabetes

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12 December 2020

Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis

1 reference

12 December 2020

Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes.

1 reference

12 December 2020

Targeting autoimmune diabetes with gene therapy

1 reference

12 December 2020

Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice

1 reference

12 December 2020

Distinct characteristics and features of allogeneic chimerism in the NOD mouse model of autoimmune diabetes

1 reference

12 December 2020

Efficient gene transfer and expression in islets by an adenoviral vector that lacks all viral genes.

1 reference

12 December 2020

Transforming growth factor-alpha and epidermal growth factor expression in human fetal gastrointestinal tract

1 reference

12 December 2020

Allogeneic hematopoietic chimerism in mice treated with sublethal myeloablation and anti-CD154 antibody: absence of graft-versus-host disease, induction of skin allograft tolerance, and prevention of recurrent autoimmunity in islet-allografted NOD/L

1 reference

12 December 2020

Adenoviral transfection of isolated pancreatic islets: a study of programmed cell death (apoptosis) and islet function

1 reference

12 December 2020

Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice

1 reference

12 December 2020

Expression of the bcl-2 gene from a defective HSV-1 amplicon vector protects pancreatic beta-cells from apoptosis

1 reference

12 December 2020

Overexpression of parathyroid hormone-related protein in the pancreatic islets of transgenic mice causes islet hyperplasia, hyperinsulinemia, and hypoglycemia

1 reference

12 December 2020

In vitro studies of the stimulation of insulin secretion and B-cell proliferation by rat placental lactogen-II during pregnancy in rats

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12 December 2020

Genetic engineering of dendritic cells to express immunosuppressive molecules (viral IL-10, TGF-beta, and CTLA4Ig).

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12 December 2020

A20 inhibits cytokine-induced apoptosis and nuclear factor kappaB-dependent gene activation in islets

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12 December 2020

Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene

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12 December 2020

Oral tolerance: immunologic mechanisms and treatment of animal and human organ-specific autoimmune diseases by oral administration of autoantigens

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12 December 2020

Adenovirus-mediated in vivo gene transfer and expression in normal rat pancreas.

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12 December 2020

The Reg Gene and Islet Cell Repair and Renewal in Type 1 Diabetes

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12 December 2020

Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta- induced cytotoxicity and reduces nitric oxide production

1 reference

12 December 2020

The beta cell transcription factors and development of the pancreas

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12 December 2020

Islet cell transplantation tolerance

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12 December 2020

Induction of immunological tolerance to islet allografts

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12 December 2020

Functional rest through intensive treatment with insulin and potassium channel openers preserves residual beta-cell function and mass in acutely diabetic BB rats.

1 reference

12 December 2020

Cytoprotection of pancreatic islets before and soon after transplantation by gene transfer of the anti-apoptotic Bcl-2 gene

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12 December 2020

Adenovirus early region 3(E3) immunomodulatory genes decrease the incidence of autoimmune diabetes in NOD mice.

1 reference

12 December 2020

Effects of prolactin and glycosylated prolactin on (pro)insulin synthesis and insulin release from cultured rat pancreatic islets

1 reference

12 December 2020

Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitro

1 reference

12 December 2020

Standardization of procedure for efficient ex vivo gene transfer into porcine pancreatic islets with cationic liposomes

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12 December 2020

Pluripotency of mesenchymal stem cells derived from adult marrow

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12 December 2020

Transplantation of islet cells across major histocompatibility barriers after total lymphoid irradiation and infusion of allogeneic bone marrow cells

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12 December 2020

Lentivirus-mediated Bcl-2 expression in betaTC-tet cells improves resistance to hypoxia and cytokine-induced apoptosis while preserving in vitro and in vivo control of insulin secretion

1 reference

12 December 2020

Outcome of human fetal pancreatic transplants according to implantation site.

1 reference

12 December 2020

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

1 reference

12 December 2020

Pancreatic islet cell survival following islet isolation: the role of cellular interactions in the pancreas

1 reference

12 December 2020

Gene therapy in transplantation

1 reference

12 December 2020

Human islet transplantation: update.

1 reference

12 December 2020

Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

1 reference

12 December 2020

Transduction of non-dividing adult human pancreatic beta cells by an integrating lentiviral vector

1 reference

12 December 2020

A single treatment with IL-4 via retrovirally transduced lymphocytes partially protects against diabetes in BioBreeding (BB) rats.

1 reference

12 December 2020

Glucose-responsive gene delivery in pancreatic Islet cells via recombinant adeno-associated viral vectors

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12 December 2020

Developmental gene expression in the human fetal pancreas

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12 December 2020

Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

1 reference

12 December 2020

Highly efficient gene transfer into cord blood nonobese diabetic/severe combined immunodeficiency repopulating cells by oncoretroviral vector particles pseudotyped with the feline endogenous retrovirus (RD114) envelope protein

1 reference

12 December 2020

Gene transduction efficiency in cells of different species by HIV and EIAV vectors

1 reference

12 December 2020

The relationship between peripheral T cell reactivity to insulin, clinical remissions and cytokine production in type 1 (insulin-dependent) diabetes mellitus

1 reference

12 December 2020

Transgenic expression of mouse proinsulin II prevents diabetes in nonobese diabetic mice

1 reference

12 December 2020

NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice

1 reference

12 December 2020

Cell fate determination from stem cells

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12 December 2020

A role for hepatocyte growth factor/scatter factor in fetal mesenchyme-induced pancreatic beta-cell growth

1 reference

12 December 2020

Gene transfer to human pancreatic endocrine cells using viral vectors

1 reference

12 December 2020

Therapeutic cloning: concepts and practicalities

1 reference

12 December 2020

Regulation of insulin secretion from beta-cell lines derived from transgenic mice insulinomas resembles that of normal beta-cells

1 reference

12 December 2020

Molecular basis of evolutionary loss of the alpha 1,3-galactosyltransferase gene in higher primates

1 reference

12 December 2020

Intramuscular administration of expression plasmids encoding interferon-gamma receptor/IgG1 or IL-4/IgG1 chimeric proteins protects from autoimmunity

1 reference

12 December 2020

Gene transfer to the nonhuman primate retina with recombinant feline immunodeficiency virus vectors.

1 reference

12 December 2020

Stem cells--hype and hope

1 reference

12 December 2020

Allogeneic chimerism induces donor-specific tolerance to simultaneous islet allografts in nonobese diabetic mice

1 reference

12 December 2020

Growth Factor/Matrix-Induced Proliferation of Human Adult β-Cells

1 reference

12 December 2020

Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction

1 reference

12 December 2020

Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells

1 reference

12 December 2020

Comparison of gene transfer efficiencies and gene expression levels achieved with equine infectious anemia virus- and human immunodeficiency virus type 1-derived lentivirus vectors

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12 December 2020

Gene transfer vectors derived from equine infectious anemia virus

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12 December 2020

A protective role for heme oxygenase expression in pancreatic islets exposed to interleukin-1beta

1 reference

12 December 2020

Mixed bone marrow chimerism as a treatment for autoimmune diabetes

1 reference

12 December 2020

Prevention of autoimmune recurrence and rejection by adenovirus-mediated CTLA4Ig gene transfer to the pancreatic graft in BB rat.

1 reference

12 December 2020

Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein

1 reference

12 December 2020

Immunoinhibitory DNA vaccine protects against autoimmune diabetes through cDNA encoding a selective CTLA-4 (CD152) ligand.

1 reference

12 December 2020

In Vitro-Generation of Islets in Long-Term Cultures of Pluripotent Stem Cells From Adult Mouse Pancreas

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12 December 2020

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets

1 reference

12 December 2020

Hepatocyte Nuclear Factor 3β is Involved in Pancreatic β-Cell-Specific Transcription of the pdx-1 Gene

1 reference

12 December 2020

Impact of bone marrow transplantation on type I diabetes

1 reference

12 December 2020

Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

1 reference

12 December 2020

Targeted integration of foreign DNA into a defined locus on chromosome 19 in K562 cells using AAV-derived components

1 reference

12 December 2020

Mixed xenogeneic chimerism (mouse rat-->mouse) to induce donor-specific tolerance to sequential or simultaneous islet xenografts

1 reference

12 December 2020

Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide.

1 reference

12 December 2020

Islet transplantation

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12 December 2020

Dendritic cells as regulators of immune reactivity: implications for transplantation

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12 December 2020

Tolerance induction for islet transplantation

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12 December 2020

Liposome mediated in vitro transfection of pancreatic islet cells

1 reference

12 December 2020

T-cell insulitis found in anti-GAD65 diabetes with residual beta-cell function. A case report

1 reference

12 December 2020

Long-term reversal of established autoimmunity upon transient blockade of the LFA-1/intercellular adhesion molecule-1 pathway.

1 reference

12 December 2020

Cell-based therapy for insulin-dependent diabetes mellitus

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12 December 2020

Expression of adenoviral E3 transgenes in beta cells prevents autoimmune diabetes

1 reference

12 December 2020

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

12 December 2020

Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand

1 reference

12 December 2020

Characterization of multipotent adult progenitor cells, a subpopulation of mesenchymal stem cells

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12 December 2020

Chimerism-induced remission of overt diabetes in nonobese diabetic mice

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12 December 2020

Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation

1 reference

12 December 2020

Prevention of autoimmune insulitis in nonobese diabetic mice by expression of major histocompatibility complex class I Ld molecules

1 reference

12 December 2020

Transplantation of islets of Langerhans: new developments.

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12 December 2020

Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes

1 reference

12 December 2020

Degradable polymeric carrier for the delivery of IL-10 plasmid DNA to prevent autoimmune insulitis of NOD mice

1 reference

12 December 2020

Heme oxygenase-1 protects pancreatic beta cells from apoptosis caused by various stimuli

1 reference

12 December 2020

Islet beta-cell regeneration and reg genes

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12 December 2020

Immunopathogenesis and immunotherapy of type 1 diabetes

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12 December 2020

Targeted integration of adeno-associated virus-derived plasmids in transfected human cells.

1 reference

12 December 2020

Adenoviral vector-mediated insulin gene transfer in the mouse pancreas corrects streptozotocin-induced hyperglycemia.

1 reference

12 December 2020

Insulin-like growth factor-II and transforming growth factor-alpha in developing human fetal pancreatic islets.

1 reference

12 December 2020

Utility of adenoviral-mediated Fas ligand gene transfer to modulate islet allograft survival

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12 December 2020

Combined administration of plasmids encoding IL-4 and IL-10 prevents the development of autoimmune diabetes in nonobese diabetic mice

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12 December 2020

Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector

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12 December 2020

Vaccination with glutamic acid decarboxylase plasmid DNA protects mice from spontaneous autoimmune diabetes and B7/CD28 costimulation circumvents that protection

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12 December 2020

Regulatory natural killer T cells protect against spontaneous and recurrent type 1 diabetes

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12 December 2020

Protective effect of CTLA4Ig secreted by transgenic fetal pancreas allografts

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12 December 2020

Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice

1 reference

12 December 2020

Rat Endocrine Pancreatic Development in Relation to Two Homeobox Gene Products (Pdx-1 and Nkx 6.1)

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12 December 2020

A newly discovered role of transcription factors involved in pancreas development and the pathogenesis of diabetes mellitus

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12 December 2020

Genetic modification of an islet tumor cell line inhibits its rejection.

1 reference

12 December 2020

Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors

1 reference

12 December 2020

TGF-beta1 somatic gene therapy prevents autoimmune disease in nonobese diabetic mice

1 reference

12 December 2020

Secretion of CTLA4Ig by an SV40 T antigen-transformed islet cell line inhibits graft rejection against the neoantigen

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12 December 2020

Ex vivo expansion of human pancreatic endocrine cells

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12 December 2020

CTLA4-Ig prolongs survival of microencapsulated rabbit islet xenografts in spontaneously diabetic Nod mice

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12 December 2020

Additive efficacy of CTLA4Ig and OX40Ig secreted by genetically modified grafts

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12 December 2020

Overexpression of insulin-like growth factor-II in transgenic mice is associated with pancreatic islet cell hyperplasia

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12 December 2020

Sustained proliferation of PDX-1 cells derived from human islets

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12 December 2020

Major histocompatibility complex class I peptide-pulsed host dendritic cells induce antigen-specific acquired thymic tolerance to islet cells

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12 December 2020

Contribution of adenoviral-mediated superoxide dismutase gene transfer to the reduction in nitric oxide-induced cytotoxicity on human islets and INS-1 insulin-secreting cells

1 reference

12 December 2020

Dominant negative MyD88 proteins inhibit interleukin-1beta /interferon-gamma -mediated induction of nuclear factor kappa B-dependent nitrite production and apoptosis in beta cells

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12 December 2020

The effect of bone marrow transplantation on survival of allogeneic pancreatic islets with short-term tacrolimus conditioning in rats

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12 December 2020

Towards gene therapy of diabetes mellitus

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12 December 2020

Phenotype, function, and in vivo migration and survival of allogeneic dendritic cell progenitors genetically engineered to express TGF-beta

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12 December 2020

Expression of CTLA4-Ig by biolistically transfected mouse islets promotes islet allograft survival

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12 December 2020

Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes.

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12 December 2020

Insulin B-chain reactive CD4 regulatory T-cells induced by oral insulin treatment protect from type 1 diabetes by blocking the cytokine secretion and pancreatic infiltration of diabetogenic effector T-cells

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12 December 2020

The natural killer T-cell ligand α-galactosylceramide prevents autoimmune diabetes in non-obese diabetic mice

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12 December 2020

Islet/pancreas transplantation: challenges for pediatrics

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12 December 2020

Targeted disruption of the alpha1,3-galactosyltransferase gene in cloned pigs

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12 December 2020

Historical and current perspectives on bone marrow transplantation for prevention and treatment of immunodeficiencies and autoimmunities.

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12 December 2020

Infection of intact human islets by a lentiviral vector

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12 December 2020

Pancreas and islet cell transplantation

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12 December 2020

Recombinant human transforming growth factor beta does not inhibit the effects of interleukin-1 beta on pancreatic islet cells

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12 December 2020

Ex vivo adenovirus-mediated gene delivery leads to long-term expression in pancreatic islet transplants

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12 December 2020

Apoptosis in the Pancreatic Islet Cells of the Neonatal Rat Is Associated with a Reduced Expression of Insulin-Like Growth Factor II that May Act as a Survival Factor*

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12 December 2020

Islet cell transplantation: the future?

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12 December 2020

The stimulatory effect of growth hormone, prolactin, and placental lactogen on beta-cell proliferation is not mediated by insulin-like growth factor-I

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12 December 2020

Efficient gene transfer to pancreatic islets mediated by adenoviral vectors.

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12 December 2020

Proteins linked to a protein transduction domain efficiently transduce pancreatic islets

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12 December 2020

Decreased alloreactivity to human islets secreting recombinant viral interleukin 10.

1 reference

12 December 2020

Retroviral delivery of viral interleukin-10 into myeloid dendritic cells markedly inhibits their allostimulatory activity and promotes the induction of T-cell hyporesponsiveness

1 reference

12 December 2020

Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

1 reference

12 December 2020

Enhancement of dendritic cell tolerogenicity by genetic modification using adenoviral vectors encoding cDNA for TGF beta 1

1 reference

12 December 2020

Manipulation of dendritic cells for tolerance induction in transplantation and autoimmune disease

1 reference

12 December 2020

Growth factor control of pancreatic B cell hyperplasia

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12 December 2020

Prolongation of cardiac allograft survival using dendritic cells treated with NF-kB decoy oligodeoxyribonucleotides

1 reference

12 December 2020

Gene transfer of the Bcl-2 gene confers cytoprotection to isolated adult porcine pancreatic islets exposed to xenoreactive antibodies and complement

1 reference

12 December 2020

Progressive pancreatic islet hyperplasia in the islet-targeted, parathyroid hormone-related protein-overexpressing mouse

1 reference

12 December 2020

Induction of Pancreatic Islet Neogenesis

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12 December 2020

Immunotherapy of NOD mice with bone marrow-derived dendritic cells

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12 December 2020

Expression of gastrin and transforming growth factor-α during duct to islet cell differentiation in the pancreas of duct-ligated adult rats

1 reference

12 December 2020

Local expression of immunoregulatory IL-12p40 gene prolonged syngeneic islet graft survival in diabetic NOD mice

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12 December 2020

Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion

1 reference

12 December 2020

Efficient Gene Transfer to Dispersed Human Pancreatic Islet Cells In Vitro Using Adenovirus-Polylysine/DNA Complexes or Polycationic Liposomes

1 reference

12 December 2020

Evidence for the presence of type I IL-1 receptors on β-cells of islets of Langerhans

1 reference

12 December 2020

Identifiers

DOI

10.1023/A:1027306213563

1 reference

Dimensions Publication ID

9 August 2017

1006980657

0 references

1 reference