A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model (Q35581584)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

12 February 2020

title

A metabolomic and systems biology perspective on the brain of the fragile X syndrome mouse model (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

1 reference

3

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12 February 2020

Maria Vincenza Catania

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

12 February 2020

Barbara Bardoni

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

12 February 2020

Marc-Emmanuel Dumas

6

1 reference

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12 February 2020

author name string

Laetitia Davidovic

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

12 February 2020

Vincent Navratil

2

1 reference

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12 February 2020

publication date

7 September 2011

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12 February 2020

1 reference

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12 February 2020

volume

21

1 reference

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12 February 2020

issue

12

1 reference

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12 February 2020

page(s)

2190-2202

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

Making and breaking synapses through local mRNA regulation

12 February 2020

cites work

1 reference

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Heads-up: new roles for the fragile X mental retardation protein in neural stem and progenitor cells

27 July 2018

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When the human viral infectome and diseasome networks collide: towards a systems biology platform for the aetiology of human diseases.

27 July 2018

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Glutamate receptors and learning and memory

27 July 2018

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System-level comparison of protein-protein interactions between viruses and the human type I interferon system network

27 July 2018

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MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data

27 July 2018

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Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132

27 July 2018

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27 July 2018

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Fragile X mental retardation protein regulates the levels of scaffold proteins and glutamate receptors in postsynaptic densities

27 July 2018

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The genetic landscape of intellectual disability arising from chromosome X.

27 July 2018

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A novel function for fragile X mental retardation protein in translational activation

27 July 2018

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VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus-host interaction networks

27 July 2018

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Brain energetics (thought needs food).

27 July 2018

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Forkhead box, class O transcription factors in brain: regulation and behavioral manifestation

27 July 2018

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Imbalance of neocortical excitation and inhibition and altered UP states reflect network hyperexcitability in the mouse model of fragile X syndrome

27 July 2018

1 reference

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Metabolic changes in temporal lobe structures measured by HR-MAS NMR at early stage of electrogenic rat epilepsy

27 July 2018

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Circuit and plasticity defects in the developing somatosensory cortex of FMR1 knock-out mice.

27 July 2018

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The fragile X prevalence paradox

27 July 2018

1 reference

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Identification of small molecules rescuing fragile X syndrome phenotypes in Drosophila

27 July 2018

1 reference

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Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome

27 July 2018

1 reference

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On BC1 RNA and the fragile X mental retardation protein.

27 July 2018

1 reference

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KEGG for linking genomes to life and the environment

27 July 2018

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Metabotyping of Caenorhabditis elegans reveals latent phenotypes

27 July 2018

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GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations

27 July 2018

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27 July 2018

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The glutamate-glutamine cycle is not stoichiometric: fates of glutamate in brain

27 July 2018

1 reference

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Refining the roles of GABAergic signaling during neural circuit formation

27 July 2018

1 reference

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The pathophysiology of fragile x syndrome.

27 July 2018

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FMRP mediates mGluR5-dependent translation of amyloid precursor protein

27 July 2018

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Metabolic fingerprints of altered brain growth, osmoregulation and neurotransmission in a Rett syndrome model

27 July 2018

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The application of NMR-based metabonomics in neurological disorders

27 July 2018

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Genetics and pathophysiology of mental retardation

27 July 2018

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The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons

27 July 2018

1 reference

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High resolution 1H NMR-based metabolomics indicates a neurotransmitter cycling deficit in cerebral tissue from a mouse model of Batten disease

27 July 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

27 July 2018

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FMRP RNA targets: identification and validation

27 July 2018

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Functions and pathophysiological roles of phospholipase D in the brain

27 July 2018

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Nicotinic receptor modulation of neurotransmitter release in the cerebellum

27 July 2018

1 reference

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The fragile X protein controls microtubule-associated protein 1B translation and microtubule stability in brain neuron development.

27 July 2018

1 reference

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Biochemical evidence for the association of fragile X mental retardation protein with brain polyribosomal ribonucleoparticles

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

APP processing and synaptic function

27 July 2018

1 reference

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Metabonomics: a platform for studying drug toxicity and gene function

27 July 2018

1 reference

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Alterations of amino acids and monoamine metabolism in male Fmr1 knockout mice: a putative animal model of the human fragile X mental retardation syndrome

27 July 2018

1 reference

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Fragile X mental retardation protein targets G quartet mRNAs important for neuronal function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

27 July 2018

1 reference

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Abnormal development of dendritic spines in FMR1 knock-out mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Alterations in Purkinje cell spines of calbindin D-28 k and parvalbumin knock-out mice.

27 July 2018

1 reference

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Novel isoforms of the fragile X related protein FXR1P are expressed during myogenesis

27 July 2018

1 reference

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The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation

27 July 2018

1 reference

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The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2

27 July 2018

1 reference

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Delayed stabilization of dendritic spines in fragile X mice

27 July 2018

1 reference

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Expression of the GABAergic system in animal models for fragile X syndrome and fragile X associated tremor/ataxia syndrome (FXTAS).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Fragile X syndrome and epilepsy

26 September 2018

1 reference

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Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder

26 September 2018

1 reference

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Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Rho GTPases: role in dendrite and axonal growth, mental retardation, and axonal regeneration

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Enrichment or depletion of a GO category within a class of genes: which test?

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

The fragile X syndrome: exploring its molecular basis and seeking a treatment.

26 September 2018

1 reference

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CLIP: a method for identifying protein-RNA interaction sites in living cells

26 September 2018

1 reference

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Age-dependent and selective impairment of long-term potentiation in the anterior piriform cortex of mice lacking the fragile X mental retardation protein.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Metabolic characterization of distinct neuroanatomical regions in rats by magic angle spinning 1H nuclear magnetic resonance spectroscopy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Gi2 signaling enhances proliferation of neural progenitor cells in the developing brain

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Taurine as a modulator of excitatory and inhibitory neurotransmission

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

The fragile X mental retardation protein FMRP binds elongation factor 1A mRNA and negatively regulates its translation in vivo

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Broad-Ranging Natural Metabotype Variation Drives Physiological Plasticity in Healthy Control Inbred Rat Strains

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3227107

Fmr1 knockout mice: a model to study fragile X mental retardation. The Dutch-Belgian Fragile X Consortium

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21900387

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GR.116764.110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21900387 AND SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

21900387

1 reference