Connexins protect mouse pancreatic β cells against apoptosis. (Q35578551)

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16 January 2020

title

Connexins protect mouse pancreatic β cells against apoptosis (English)

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16 January 2020

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2

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Jacques-Antoine Haefliger

16 January 2020

8

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16 January 2020

author name string

Philippe Klee

1

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16 January 2020

Helena Pontes

3

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16 January 2020

Manon Cederroth

4

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16 January 2020

Anne Charollais

5

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16 January 2020

Dorothée Caille

6

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16 January 2020

Aurore Britan

7

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16 January 2020

Paolo Meda

9

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16 January 2020

language of work or name

English

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publication date

7 November 2011

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Journal of Clinical Investigation

16 January 2020

published in

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16 January 2020

volume

121

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16 January 2020

issue

12

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16 January 2020

page(s)

4870-4879

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Connexins: Key Mediators of Endocrine Function

16 January 2020

cites work

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Connexin43 interacts with βarrestin: a pre-requisite for osteoblast survival induced by parathyroid hormone

27 July 2018

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Influence of genetic polymorphisms on the pharmacokinetics and pharmaco-dynamics of sulfonylurea drugs.

27 July 2018

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The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

27 July 2018

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Recent progress in research on beta-cell apoptosis by cytokines

27 July 2018

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Lack of "hemichannel" activity in insulin-producing cells

27 July 2018

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A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells

27 July 2018

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The mechanisms of alloxan- and streptozotocin-induced diabetes

27 July 2018

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Cx36-mediated coupling reduces beta-cell heterogeneity, confines the stimulating glucose concentration range, and affects insulin release kinetics

27 July 2018

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Involvement of gap junctional communication in secretion

27 July 2018

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

27 July 2018

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Loss of connexin36 channels alters beta-cell coupling, islet synchronization of glucose-induced Ca2 and insulin oscillations, and basal insulin release.

27 July 2018

1 reference

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Connexin-36 contributes to control function of insulin-producing cells.

27 July 2018

1 reference

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Connexin 36 controls synchronization of Ca2 oscillations and insulin secretion in MIN6 cells.

27 July 2018

1 reference

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Emerging issues of connexin channels: biophysics fills the gap.

27 July 2018

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A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

27 July 2018

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Transduction of cell survival signals by connexin-43 hemichannels

27 July 2018

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Visual transmission deficits in mice with targeted disruption of the gap junction gene connexin36.

27 July 2018

1 reference

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Mitochondria as the central control point of apoptosis

27 July 2018

1 reference

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Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance

27 July 2018

1 reference

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The harmony of the spheres: inducible nitric oxide synthase and related genes in pancreatic beta cells

27 July 2018

1 reference

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Genetic Influence of the Streptozotocin-induced Insulitis and Hyperglycemia

27 July 2018

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Increase of gap junctions between pancreatic B-cells during stimulation of insulin secretion

27 July 2018

1 reference

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Effects of exposure of human islet beta-cells to normal and high glucose levels with or without gliclazide or glibenclamide.

27 July 2018

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Cx36 makes channels coupling human pancreatic beta-cells, and correlates with insulin expression

26 September 2018

1 reference

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Calcium and cell death: the mitochondrial connection.

26 September 2018

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Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets.

26 September 2018

1 reference

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Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy.

26 September 2018

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Differential sensitivity of GLUT1- and GLUT2-expressing beta cells to streptozotocin

26 September 2018

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Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin

26 September 2018

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Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

26 September 2018

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Constitutive differences in antioxidant defense status distinguish alloxan-resistant and alloxan-susceptible mice.

26 September 2018

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Cytokines induce both necrosis and apoptosis via a common Bcl-2-inhibitable pathway in rat insulin-producing cells

26 September 2018

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12 December 2020

Beta cells preferentially exchange cationic molecules via connexin 36 gap junction channels

1 reference

12 December 2020

Islet-cell-to-cell communication as basis for normal insulin secretion

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12 December 2020

Cx36 preferentially connects beta-cells within pancreatic islets

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12 December 2020

Distinction between interleukin-1-induced necrosis and apoptosis of islet cells

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12 December 2020

Gap junction development is correlated with insulin content in the pancreatic B cell

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12 December 2020

Connexin implication in the control of the murine beta-cell mass

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12 December 2020

Identifiers

DOI

10.1172/JCI40509

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22056383 AND SRC:MED&resulttype=core&format=json

16 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22056383 AND SRC:MED&resulttype=core&format=json

16 January 2020

PubMed publication ID

22056383

1 reference