Novel agents for anti-platelet therapy (Q35574825)

8 August 2017

4 references

13 March 2019

19 March 2019

17 June 2019

28 April 2021

Novel agents for anti-platelet therapy (English)

1 reference

platelet aggregation inhibitors

8 August 2017

3 references

13 March 2019

19 March 2019

17 June 2019

1 reference

28 April 2021

Xuebin Ji

1

1 reference

8 August 2017

Ming Hou

series ordinal

2

1 reference

8 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=22053759

16 December 2024

publication date

4 November 2011

5 references

full work available at URL

8 August 2017

13 March 2019

19 March 2019

17 June 2019

28 April 2021

https://jhoonline.biomedcentral.com/counter/pdf/10.1186/1756-8722-4-44

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22053759

https://europepmc.org/articles/PMC3224753

16 December 2024

file format

HyperText Markup Language

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22053759

https://europepmc.org/articles/PMC3224753?pdf=render

16 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:22053759

http://link.springer.com/content/pdf/10.1186/1756-8722-4-44.pdf

16 December 2024

1 reference

10.1186/1756-8722-4-44

https://api.crossref.org/works/10.1186/1756-8722-4-44

http://link.springer.com/article/10.1186/1756-8722-4-44/fulltext.html

16 December 2024

file format

HyperText Markup Language

1 reference

Crossref

DOI

10.1186/1756-8722-4-44

https://api.crossref.org/works/10.1186/1756-8722-4-44

Journal of Hematology & Oncology

16 December 2024

published in

5 references

8 August 2017

13 March 2019

19 March 2019

17 June 2019

28 April 2021

4

1 reference

8 August 2017

page(s)

44

1 reference

Creative Commons Attribution 2.0 Generic

8 August 2017

copyright license

4 references

13 March 2019

19 March 2019

17 June 2019

on focus list of Wikimedia project

28 April 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial

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P2Y Receptors in Health and Disease

12 July 2018

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Delineating the roles of the GPIIb/IIIa and GP-Ib-IX-V platelet receptors in mediating platelet adhesion to adsorbed fibrinogen and albumin.

12 July 2018

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Efficacy and safety of glycoprotein IIb/IIIa inhibitors during elective coronary revascularization: a meta-analysis of randomized trials performed in the era of stents and thienopyridines

12 July 2018

1 reference

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Glycoprotein IIb/IIIa inhibitors: an update on the mechanism of action and use of functional testing methods to assess antiplatelet efficacy

12 July 2018

1 reference

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Targeting von Willebrand factor and platelet glycoprotein Ib receptor

12 July 2018

1 reference

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The clinical potential of microRNAs

12 July 2018

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Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: results from the Platelet Inhibition and Patient Outcomes (PLATO) trial

12 July 2018

1 reference

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Update on the clinical development of cangrelor.

12 July 2018

1 reference

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Prasugrel: a novel platelet ADP P2Y(12) receptor antagonist.

12 July 2018

1 reference

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Safety and efficacy of abciximab as an adjunct to percutaneous coronary intervention

12 July 2018

1 reference

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State of the art of new P2Y12 antagonists.

12 July 2018

1 reference

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The potential benefits of low-molecular-weight heparins in cancer patients

12 July 2018

1 reference

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Ticagrelor versus clopidogrel in patients with acute coronary syndromes

12 July 2018

1 reference

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SCH 530348: a novel oral thrombin receptor antagonist

12 July 2018

1 reference

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SCH-530348, a thrombin receptor (PAR-1) antagonist for the prevention and treatment of atherothrombosis.

12 July 2018

1 reference

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12 July 2018

New antithrombotic drugs

1 reference

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Inhibition of von Willebrand factor-mediated platelet activation and thrombosis by the anti-von Willebrand factor A1-domain aptamer ARC1779.

12 July 2018

1 reference

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The humanized anti-glycoprotein Ib monoclonal antibody h6B4-Fab is a potent and safe antithrombotic in a high shear arterial thrombosis model in baboons.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Cilostazol as an alternative to aspirin after ischaemic stroke: a randomised, double-blind, pilot study

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

The Fab fragment of a novel anti-GPVI monoclonal antibody, OM4, reduces in vivo thrombosis without bleeding risk in rats

12 July 2018

1 reference

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Development of monoclonal antibodies that inhibit platelet adhesion or aggregation as potential anti-thrombotic drugs.

12 July 2018

1 reference

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GPVI and alpha2beta1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

The P2 receptors in platelet function.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Inhibition of platelet adhesion to collagen as a new target for antithrombotic drugs

12 July 2018

1 reference

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Platelet-collagen interaction: is GPVI the central receptor?

12 July 2018

1 reference

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Anti GPVI human antibodies neutralizing collagen-induced platelet aggregation isolated from a combinatorial phage display library.

12 July 2018

1 reference

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Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation

12 July 2018

1 reference

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Platelet aggregation inhibition with glycoprotein IIb--IIIa inhibitors

12 July 2018

1 reference

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Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trials

12 July 2018

1 reference

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Antithrombotic effect of platelet glycoprotein Ib-blocking monoclonal antibody Fab fragments in nonhuman primates.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

The effect of ticagrelor versus clopidogrel on high on-treatment platelet reactivity: combined analysis of the ONSET/OFFSET and RESPOND studies

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Oral antiplatelet therapy for atherothrombotic disease: Current evidence and new directions

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

The novel and orally active thrombin receptor antagonist E5555 (Atopaxar) inhibits arterial thrombosis without affecting bleeding time in guinea pigs

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Cilostazol for prevention of secondary stroke (CSPS 2): an aspirin-controlled, double-blind, randomised non-inferiority trial

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Adding cilostazol to dual antiplatelet therapy achieves greater platelet inhibition than high maintenance dose clopidogrel in patients with acute myocardial infarction: Results of the adjunctive cilostazol versus high maintenance dose clopidogrel in

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Addition of cilostazol reduces biological aspirin resistance in aspirin users with ischaemic stroke: a double-blind randomized clinical trial

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Improving antiplatelet therapy for atherothrombotic disease: preclinical results with SCH 530348, the first oral thrombin receptor antagonist selective for PAR-1.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

The in-vitro effects of E5555, a protease-activated receptor (PAR)-1 antagonist, on platelet biomarkers in healthy volunteers and patients with coronary artery disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Combined aspirin and cilostazol treatment is associated with reduced platelet aggregation and prevention of exercise-induced platelet activation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Basic and translational research on proteinase-activated receptors: antagonism of the proteinase-activated receptor 1 for thrombin, a novel approach to antiplatelet therapy for atherothrombotic disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Cilostazol could ameliorate platelet responsiveness to clopidogrel in patients undergoing primary percutaneous coronary intervention

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Prasugrel versus clopidogrel in patients with acute coronary syndromes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Von Willebrand factor can support platelet aggregation via interaction with activated GPIIb-IIIa and GPIb

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

GPVI levels in platelets: relationship to platelet function at high shear

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3224753

Mode of action of P2Y(12 ) antagonists as inhibitors of platelet function

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22053759

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Oral administration of the thrombin receptor antagonist E5555 (atopaxar) attenuates intimal thickening following balloon injury in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22053759

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1756-8722-4-44

1 reference

Dimensions Publication ID

8 August 2017

0 references

1 reference

8 August 2017

1 reference