The added value of ordinal analysis in clinical trials: an example in traumatic brain injury. (Q35558241)

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1 February 2020

title

The added value of ordinal analysis in clinical trials: an example in traumatic brain injury (English)

1 reference

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1 February 2020

main subject

traumatic brain injury

0 references

author

Gordon Murray

6

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1 February 2020

Andrew I Maas

7

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1 February 2020

Ewout W. Steyerberg

8

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1 February 2020

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Pablo Perel

1 reference

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1 February 2020

author name string

Bob Roozenbeek

1

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1 February 2020

Hester F Lingsma

2

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1 February 2020

Phil Edwards

4

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Ian Roberts

5

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IMPACT (International Mission on Prognosis and Clinical Trial Design in Traumatic Brain Injury) Study Group

9

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CRASH (Corticosteroid Randomisation After Significant Head Injury) Trial Collaborators

10

1 reference

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publication date

17 May 2011

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1 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586148 AND SRC:MED&resulttype=core&format=json

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volume

15

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issue

3

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page(s)

R127

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Delta inflation: a bias in the design of randomized controlled trials in critical care medicine

1 February 2020

cites work

1 reference

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A simulation study evaluating approaches to the analysis of ordinal outcome data in randomized controlled trials in traumatic brain injury: results from the IMPACT Project

12 July 2018

1 reference

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IMPACT recommendations for improving the design and analysis of clinical trials in moderate to severe traumatic brain injury

12 July 2018

1 reference

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Clinical trials in traumatic brain injury: past experience and current developments.

12 July 2018

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The Paracetamol (Acetaminophen) In Stroke (PAIS) trial: a multicentre, randomised, placebo-controlled, phase III trial

12 July 2018

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Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients

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Novel end point analytic techniques and interpreting shifts across the entire range of outcome scales in acute stroke trials.

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Adjustment for strong predictors of outcome in traumatic brain injury trials: 25% reduction in sample size requirements in the IMPACT study.

12 July 2018

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Proportional odds logistic regression--effective means of dealing with limited uncertainty in dichotomizing clinical outcomes

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The cost of dichotomising continuous variables

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NXY-059 for acute ischemic stroke

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Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial

12 July 2018

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Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months

12 July 2018

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Design and analysis of phase III trials with ordered outcome scales: the concept of the sliding dichotomy

12 July 2018

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Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial

12 July 2018

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FUNCTIONAL EVALUATION: THE BARTHEL INDEX

12 July 2018

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Cerebral vascular accidents in patients over the age of 60. II. Prognosis

12 July 2018

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Clinical trials in head injury

12 July 2018

1 reference

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Why have recent trials of neuroprotective agents in head injury failed to show convincing efficacy? A pragmatic analysis and theoretical considerations

12 July 2018

1 reference

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Baseline characteristics and statistical power in randomized controlled trials: selection, prognostic targeting, or covariate adjustment?

12 July 2018

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Early surgery versus initial conservative treatment in patients with spontaneous supratentorial intracerebral haematomas in the International Surgical Trial in Intracerebral Haemorrhage (STICH): a randomised trial

26 September 2018

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Clinical trials in acute myocardial infarction: should we adjust for baseline characteristics?

26 September 2018

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Evaluation of designs for clinical trials of neuroprotective agents in head injury. European Brain Injury Consortium

26 September 2018

1 reference

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Can We Improve the Statistical Analysis of Stroke Trials?

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21586148

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Measurement in clinical trials: a neglected issue for statisticians?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21586148

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glycine antagonist (gavestinel) in neuroprotection (GAIN International) in patients with acute stroke: a randomised controlled trial. GAIN International Investigators

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21586148

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/CC10240

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586148 AND SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21586148 AND SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

21586148

1 reference