Transglutaminase 2 and its role in pulmonary fibrosis. (Q35527871)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21700912 AND SRC:MED&resulttype=core&format=json

5 February 2020

title

Transglutaminase 2 and its role in pulmonary fibrosis (English)

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5 February 2020

1 reference

5

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5 February 2020

Thomas Thatcher

7

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5 February 2020

author name string

Keith C Olsen

1

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5 February 2020

Ramil E Sapinoro

2

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5 February 2020

R M Kottmann

3

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5 February 2020

Ajit A Kulkarni

4

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5 February 2020

Gail V W Johnson

6

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5 February 2020

Richard P Phipps

8

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5 February 2020

Patricia J Sime

9

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5 February 2020

language of work or name

English

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publication date

23 June 2011

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American Journal of Respiratory and Critical Care Medicine

5 February 2020

published in

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5 February 2020

volume

184

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issue

6

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5 February 2020

page(s)

699-707

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RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 α5β1 integrin co-signaling

5 February 2020

cites work

1 reference

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Determinants of initiation and progression of idiopathic pulmonary fibrosis

12 July 2018

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Increased TG2 expression can result in induction of transforming growth factor beta1, causing increased synthesis and deposition of matrix proteins, which can be regulated by nitric oxide

12 July 2018

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Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders.

12 July 2018

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Tissue transglutaminase contributes to interstitial renal fibrosis by favoring accumulation of fibrillar collagen through TGF-beta activation and cell infiltration.

12 July 2018

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Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling

12 July 2018

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Calphostin C-induced apoptosis is mediated by a tissue transglutaminase-dependent mechanism involving the DLK/JNK signaling pathway

12 July 2018

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Transglutaminase 2 activity promotes membrane resealing after mechanical damage in the lung cancer cell line A549.

12 July 2018

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Extracellular transglutaminase 2 is catalytically inactive, but is transiently activated upon tissue injury

12 July 2018

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TGFbeta mediates activation of transglutaminase 2 in response to oxidative stress that leads to protein aggregation

12 July 2018

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Cellular and molecular mechanisms of fibrosis

12 July 2018

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Murine models of pulmonary fibrosis.

12 July 2018

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Molecular targets in pulmonary fibrosis: the myofibroblast in focus.

12 July 2018

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Cystamine ameliorates liver fibrosis induced by carbon tetrachloride via inhibition of tissue transglutaminase

12 July 2018

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Transglutaminase 2 inhibitors and their therapeutic role in disease states

12 July 2018

1 reference

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Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases

12 July 2018

1 reference

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Tissue transglutaminase expression promotes cell attachment, invasion and survival in breast cancer cells

12 July 2018

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Incidence and prevalence of idiopathic pulmonary fibrosis

12 July 2018

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Tissue transglutaminase (TG2)--a wound response enzyme.

12 July 2018

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Tissue transglutaminase: from biological glue to cell survival cues

12 July 2018

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Idiopathic pulmonary fibrosis: challenges and opportunities for the clinician and investigator

12 July 2018

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Tissue transglutaminase in normal and abnormal wound healing: review article

12 July 2018

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Ghalpha/tissue transglutaminase 2: an emerging G protein in signal transduction

12 July 2018

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Cell migration: integrating signals from front to back

12 July 2018

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Pathogenetic mechanisms in usual interstitial pneumonia/idiopathic pulmonary fibrosis.

12 July 2018

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Opposing roles of Ras/Raf oncogenes and the MEK1/ERK signaling module in regulation of expression and adhesive function of surface transglutaminase

12 July 2018

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Activation of in situ tissue transglutaminase by intracellular reactive oxygen species

12 July 2018

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Transglutaminases: crosslinking enzymes with pleiotropic functions

12 July 2018

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Making sense of latent TGFbeta activation

12 July 2018

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Transglutaminases: nature's biological glues

12 July 2018

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Cell-surface transglutaminase promotes fibronectin assembly via interaction with the gelatin-binding domain of fibronectin: a role in TGFbeta-dependent matrix deposition

12 July 2018

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Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin

12 July 2018

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12 July 2018

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Targeted inactivation of Gh/tissue transglutaminase II

12 July 2018

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Tissue transglutaminase is essential for neurite outgrowth in human neuroblastoma SH-SY5Y cells

12 July 2018

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Tissue transglutaminase is an integrin-binding adhesion coreceptor for fibronectin

12 July 2018

1 reference

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Tissue transglutaminase: an enzyme with a split personality

12 July 2018

1 reference

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Regulated expression of tissue transglutaminase in Swiss 3T3 fibroblasts: effects on the processing of fibronectin, cell attachment, and cell death

12 July 2018

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Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

12 July 2018

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The role of transglutaminase in the rat subtotal nephrectomy model of renal fibrosis

12 July 2018

1 reference

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Gh: a GTP-binding protein with transglutaminase activity and receptor signaling function

12 July 2018

1 reference

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Transforming growth factor beta 1 is present at sites of extracellular matrix gene expression in human pulmonary fibrosis

12 July 2018

1 reference

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Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3208598

Transglutaminase inhibition ameliorates experimental diabetic nephropathy.

12 July 2018

1 reference

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PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis

26 September 2018

1 reference

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Crosslinking and G-protein functions of transglutaminase 2 contribute differentially to fibroblast wound healing responses.

26 September 2018

1 reference

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Expression of cytosolic and membrane associated tissue transglutaminase in rat hepatic stellate cells and its upregulation during transdifferentiation to myofibroblasts in culture

26 September 2018

1 reference

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Transglutaminase-mediated cross-linking is involved in the stabilization of extracellular matrix in human liver fibrosis

26 September 2018

1 reference

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Transglutaminase Inhibition Reduces Fibrosis and Preserves Function in Experimental Chronic Kidney Disease

26 September 2018

1 reference

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Stimulation of integrin-mediated cell contractility by fibronectin polymerization

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21700912

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lung cytokine production in bleomycin-induced pulmonary fibrosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21700912

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21700912

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1164/RCCM.201101-0013OC

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21700912 AND SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21700912 AND SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

21700912

1 reference