Long-lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC1 activity (Q35527222)

8 August 2017

title

Long-lived Snell dwarf mice display increased proteostatic mechanisms that are not dependent on decreased mTORC1 activity (English)

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8 August 2017

5

Richard A Miller

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8 August 2017

Joshua C Drake

1

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8 August 2017

Danielle R Bruns

2

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8 August 2017

Frederick F Peelor

3

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8 August 2017

Laurie M Biela

4

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8 August 2017

Benjamin F Miller

6

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8 August 2017

Karyn L Hamilton

7

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8 August 2017

publication date

26 February 2015

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8 August 2017

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8 August 2017

volume

14

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8 August 2017

issue

3

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8 August 2017

page(s)

474-482

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Long-lived crowded-litter mice have an age-dependent increase in protein synthesis to DNA synthesis ratio and mTORC1 substrate phosphorylation

8 August 2017

cites work

1 reference

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Sulfur-based redox alterations in long-lived Snell dwarf mice.

27 July 2018

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Assessment of mitochondrial biogenesis and mTORC1 signaling during chronic rapamycin feeding in male and female mice

27 July 2018

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Nutrient signaling in protein homeostasis: an increase in quantity at the expense of quality

27 July 2018

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Decreased levels of proapoptotic factors and increased key regulators of mitochondrial biogenesis constitute new potential beneficial features of long-lived growth hormone receptor gene-disrupted mice.

27 July 2018

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mTOR signaling in growth control and disease

27 July 2018

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A perspective on the determination of mitochondrial biogenesis

27 July 2018

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A comprehensive assessment of mitochondrial protein synthesis and cellular proliferation with age and caloric restriction

27 July 2018

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Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation

27 July 2018

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Proteome half-life dynamics in living human cells

27 July 2018

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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

27 July 2018

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Proteasomal defense of oxidative protein modifications.

27 July 2018

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Hormone-treated snell dwarf mice regain fertility but remain long lived and disease resistant

27 July 2018

1 reference

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Enzymatic reactions involved in the repair of oxidized proteins.

27 July 2018

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The maintenance of the accuracy of protein synthesis and its relevance to ageing

27 July 2018

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Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production

27 July 2018

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Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle

27 July 2018

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Dwarf mice and the ageing process.

27 July 2018

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Intracellular protein catabolism and its control during nutrient deprivation and supply

27 July 2018

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Protein modification in aging

27 July 2018

1 reference

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Protein oxidation and aging

27 July 2018

1 reference

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The measurement of protein synthesis for assessing proteostasis in studies of slowed aging

27 July 2018

1 reference

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Superior proteome stability in the longest lived animal

26 September 2018

1 reference

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Calorie restriction does not increase short-term or long-term protein synthesis

26 September 2018

1 reference

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Augmented autophagy pathways and MTOR modulation in fibroblasts from long-lived mutant mice

26 September 2018

1 reference

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Acute {beta}-adrenergic stimulation does not alter mitochondrial protein synthesis or markers of mitochondrial biogenesis in adult men.

26 September 2018

1 reference

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Ribosomal protein S6 kinase 1 signaling regulates mammalian life span

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406676

Measurement of protein turnover rates by heavy water labeling of nonessential amino acids

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406676

Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice

26 September 2018

1 reference

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Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4406676

Growth curves and survival characteristics of the animals used in the Biomarkers of Aging Program

26 September 2018

1 reference

12 December 2020

The Snell dwarf mutation Pit1(dw) can increase life span in mice

1 reference

12 December 2020

Effects of the Pit1 mutation on the insulin signaling pathway: implications on the longevity of the long-lived Snell dwarf mouse

1 reference

12 December 2020

Akt/PKB and p38 MAPK signaling, translational initiation and longevity in Snell dwarf mouse livers

1 reference

12 December 2020

Identifiers

DOI

10.1111/ACEL.12329

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8 August 2017

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8 August 2017

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