Nuclear receptors license phagocytosis by trem2 myeloid cells in mouse models of Alzheimer's disease. (Q35515633)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25904803 AND SRC:MED&resulttype=core&format=json

6 March 2020

title

Nuclear receptors license phagocytosis by trem2 myeloid cells in mouse models of Alzheimer's disease (English)

1 reference

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6 March 2020

0 references

1 reference

6

1 reference

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6 March 2020

Bruce T Lamb

8

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6 March 2020

7

Richard M Ransohoff

1 reference

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6 March 2020

author name string

Julie C Savage

1

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6 March 2020

Taylor Jay

2

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6 March 2020

Elanda Goduni

3

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6 March 2020

Caitlin Quigley

4

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6 March 2020

Monica M Mariani

5

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6 March 2020

Gary E Landreth

9

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6 March 2020

language of work or name

English

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publication date

1 April 2015

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25904803 AND SRC:MED&resulttype=core&format=json

6 March 2020

published in

Journal of Neuroscience

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6 March 2020

volume

35

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6 March 2020

issue

16

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6 March 2020

page(s)

6532-6543

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describes a project that uses

6 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4405560/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology

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Variant of TREM2 Associated with the Risk of Alzheimer's Disease

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

12 July 2018

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12 July 2018

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12 July 2018

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Mechanisms of phagocytosis in macrophages

12 July 2018

1 reference

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Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system

12 July 2018

1 reference

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Bexarotene nanocrystal-Oral and parenteral formulation development, characterization and pharmacokinetic evaluation.

12 July 2018

1 reference

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Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia

26 September 2018

1 reference

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A plaque-specific antibody clears existing β-amyloid plaques in Alzheimer's disease mice

26 September 2018

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PPARγ/RXRα-induced and CD36-mediated microglial amyloid-β phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice.

26 September 2018

1 reference

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Bacterial sensor triggering receptor expressed on myeloid cells-2 regulates the mucosal inflammatory response.

26 September 2018

1 reference

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Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.

26 September 2018

1 reference

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Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease.

26 September 2018

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Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

26 September 2018

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Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

26 September 2018

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Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

26 September 2018

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High-yield isolation of murine microglia by mild trypsinization.

26 September 2018

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Co-expression of multiple transgenes in mouse CNS: a comparison of strategies

26 September 2018

1 reference

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Amyloid fibrils activate tyrosine kinase-dependent signaling and superoxide production in microglia.

26 September 2018

1 reference

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Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4405560

Cutting Edge: TREM-2 Attenuates Macrophage Activation

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25904803

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1523/JNEUROSCI.4586-14.2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25904803 AND SRC:MED&resulttype=core&format=json

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25904803 AND SRC:MED&resulttype=core&format=json

6 March 2020

PubMed publication ID

25904803

1 reference