The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells (Q35469548)

8 August 2017

title

The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells (English)

1 reference

8 August 2017

Qing-Bai She

1

1 reference

8 August 2017

David B Solit

2

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8 August 2017

Qing Ye

3

1 reference

8 August 2017

Kathryn E O'Reilly

4

1 reference

8 August 2017

Jose Lobo

5

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8 August 2017

Neal Rosen

6

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8 August 2017

publication date

1 October 2005

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8 August 2017

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8 August 2017

volume

8

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8 August 2017

issue

4

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8 August 2017

page(s)

287-297

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KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib

8 August 2017

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Inhibition of BAD phosphorylation either at serine 112 via extracellular signal-regulated protein kinase cascade or at serine 136 via Akt cascade sensitizes human ovarian cancer cells to cisplatin.

12 July 2018

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14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation

12 July 2018

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12 July 2018

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12 July 2018

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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

12 July 2018

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12 July 2018

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12 July 2018

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Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/Akt pathway

12 July 2018

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12 July 2018

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12 July 2018

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Topical treatment with inhibitors of the phosphatidylinositol 3'-kinase/Akt and Raf/mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways reduces melanoma development in severe combined immunodeficient mice

12 July 2018

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Resistance to gefitinib in PTEN-null HER-overexpressing tumor cells can be overcome through restoration of PTEN function or pharmacologic modulation of constitutive phosphatidylinositol 3'-kinase/Akt pathway signaling.

26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3203692

The epidermal growth factor receptor pathway mediates resistance to sequential administration of radiation and chemotherapy in primary human glioblastoma cells in a RAS-dependent manner.

26 September 2018

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The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells

26 September 2018

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26 September 2018

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26 September 2018

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Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification

26 September 2018

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12 December 2020

Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest

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12 December 2020

Epidermal growth factor receptor-targeted therapy with C225 and cisplatin in patients with head and neck cancer

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

10.1016/J.CCR.2005.09.006

Identifiers

DOI

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8 August 2017

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8 August 2017

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