Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance (Q35379041)

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12 February 2020

title

Mitotic centromere-associated kinesin (MCAK) mediates paclitaxel resistance (English)

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12 February 2020

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4

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12 February 2020

author name string

Anutosh Ganguly

1

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12 February 2020

Hailing Yang

2

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12 February 2020

Mesias Pedroza

3

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12 February 2020

Fernando Cabral

5

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12 February 2020

language of work or name

English

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publication date

7 September 2011

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Journal of Biological Chemistry

12 February 2020

published in

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12 February 2020

volume

286

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12 February 2020

issue

42

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12 February 2020

page(s)

36378-36384

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Overexpression of mitotic centromere-associated Kinesin stimulates microtubule detachment and confers resistance to paclitaxel

12 February 2020

cites work

1 reference

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Paclitaxel-Dependent Cell Lines Reveal a Novel Drug Activity

27 July 2018

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Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules

27 July 2018

1 reference

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MCAK and paclitaxel have differential effects on spindle microtubule organization and dynamics.

27 July 2018

1 reference

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Cell cycle dependent degradation of MCAK: evidence against a role in anaphase chromosome movement

27 July 2018

1 reference

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The spindle-assembly checkpoint in space and time

27 July 2018

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A new method reveals microtubule minus ends throughout the meiotic spindle

27 July 2018

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Centrosome fragments and microtubules are transported asymmetrically away from division plane in anaphase

27 July 2018

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Depletion of centromeric MCAK leads to chromosome congression and segregation defects due to improper kinetochore attachments

27 July 2018

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27 July 2018

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Expression of class III beta-tubulin reduces microtubule assembly and confers resistance to paclitaxel

27 July 2018

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Microtubule release from the centrosome in migrating cells

27 July 2018

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The microtubule-destabilizing kinesin XKCM1 regulates microtubule dynamic instability in cells

27 July 2018

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A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

27 July 2018

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Mitotic centromere-associated kinesin is important for anaphase chromosome segregation

27 July 2018

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Multiple forms of tubulin: different gene products and covalent modifications

27 July 2018

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Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes.

27 July 2018

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Microtubule release from the centrosome

27 July 2018

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Analysis of MAP 4 function in living cells using green fluorescent protein (GFP) chimeras

27 July 2018

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Mutations in alpha- and beta-tubulin affect spindle formation in Chinese hamster ovary cells

27 July 2018

1 reference

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Dynamic instability of microtubule growth

27 July 2018

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Isolation of Chinese hamster ovary cell mutants requiring the continuous presence of taxol for cell division

27 July 2018

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Beyond self-assembly: from microtubules to morphogenesis

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196137

In vivo microtubules are copolymers of available beta-tubulin isotypes: localization of each of six vertebrate beta-tubulin isotypes using polyclonal antibodies elicited by synthetic peptide antigens

27 July 2018

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Structure and utilization of tubulin isotypes

27 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196137

Taxol-dependent mutants of Chinese hamster ovary cells with alterations in alpha- and beta-tubulin

27 July 2018

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Expression and function of beta-tubulin isotypes in Chinese hamster ovary cells.

27 July 2018

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Cell line-specific differences in the control of cell cycle progression in the absence of mitosis

27 July 2018

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27 July 2018

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Resistance to antimitotic drugs in Chinese hamster ovary cells correlates with changes in the level of polymerized tubulin

27 July 2018

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Tumoral and tissue-specific expression of the major human beta-tubulin isotypes

27 July 2018

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Kin I kinesins are microtubule-destabilizing enzymes

21 January 2018

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Inhibition of cell migration and cell division correlates with distinct effects of microtubule inhibiting drugs

21 January 2018

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Actomyosin-based Retrograde Flow of Microtubules in the Lamella of Migrating Epithelial Cells Influences Microtubule Dynamic Instability and Turnover and Is Associated with Microtubule Breakage and Treadmilling

21 January 2018

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Katanin disrupts the microtubule lattice and increases polymer number in C. elegans meiosis.

21 January 2018

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21 January 2018

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A beta-tubulin leucine cluster involved in microtubule assembly and paclitaxel resistance.

21 January 2018

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Paclitaxel-dependent mutants have severely reduced microtubule assembly and reduced tubulin synthesis.

21 January 2018

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Overexpression of class I, II or IVb beta-tubulin isotypes in CHO cells is insufficient to confer resistance to paclitaxel.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3196137

26 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21903575

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Peripheral, non-centrosome-associated microtubules contribute to spindle formation in centrosome-containing cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21903575

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CHO mutants resistant to colchicine, colcemid or griseofulvin have an altered beta-tubulin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21903575

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.296483

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903575 AND SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903575 AND SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

21903575

1 reference