DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer. (Q35360590)

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7 November 2019

title

DNA microsatellite instability and mismatch repair protein loss in adenomas presenting in hereditary non-polyposis colorectal cancer (English)

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7 November 2019

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5

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7 November 2019

author name string

H Iino

1

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7 November 2019

L Simms

2

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7 November 2019

J Young

3

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7 November 2019

J Arnold

4

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7 November 2019

S I Webb

6

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7 November 2019

K L Furlong

7

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7 November 2019

B Leggett

8

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7 November 2019

J R Jass

9

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7 November 2019

language of work or name

English

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publication date

1 July 2000

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7 November 2019

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7 November 2019

volume

47

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7 November 2019

issue

1

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7 November 2019

page(s)

37-42

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Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways

7 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?

27 July 2018

1 reference

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Accumulated clonal genetic alterations in familial and sporadic colorectal carcinomas with widespread instability in microsatellite sequences

27 July 2018

1 reference

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Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis, and sporadic colon cancer.

27 July 2018

1 reference

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MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis

27 July 2018

1 reference

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A comprehensive genetic map of the human genome based on 5,264 microsatellites

27 July 2018

1 reference

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Microsatellite instability in cancer of the proximal colon

27 July 2018

1 reference

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Clues to the pathogenesis of familial colorectal cancer

27 July 2018

1 reference

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Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death

27 July 2018

1 reference

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Mechanism of activation of the TGF-beta receptor

27 July 2018

1 reference

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A CA repeat 30 – 70 KB downstream from the adenomatous polyposis coli (APC) gene

27 July 2018

1 reference

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A second-generation linkage map of the human genome

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

An Alu variable polyA repeat polymorphism upstream of L-myc at 1p32.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Choice of management strategy for colorectal cancer based on a diagnostic immunohistochemical test for defective mismatch repair

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Frameshift mutations at mononucleotide repeats in caspase-5 and other target genes in endometrial and gastrointestinal cancer of the microsatellite mutator phenotype

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

CDX2, a human homologue of Drosophila caudal, is mutated in both alleles in a replication error positive colorectal cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Mutation of the type II transforming growth factor-beta receptor is coincident with the transformation of human colon adenomas to malignant carcinomas.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred

26 September 2018

1 reference

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Somatic microsatellite mutations as molecular tumor clocks

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

Frameshift mutator mutations

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability

8 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1727981

The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)

8 December 2018

1 reference

12 December 2020

Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients

1 reference

12 December 2020

Hereditary non-polyposis colorectal cancer — morphologies, genes and mutations

1 reference

12 December 2020

Three dinucleotide repeat polymorphisms proximal to the D2S123 locus

1 reference

12 December 2020

Interval cancers in hereditary non-polyposis colorectal cancer (Lynch syndrome)

1 reference

12 December 2020

Aggressive polyps in hereditary nonpolyposis colorectal cancer: targets for screening

1 reference

12 December 2020

Genetic instability associated with adenoma to carcinoma progression in hereditary nonpolyposis colon cancer

1 reference

12 December 2020

Colorectal adenomas in surgical specimens from subjects with hereditary non-polyposis colorectal cancer

1 reference

12 December 2020

Requirement of the yeast MSH3 and MSH6 genes for MSH2-dependent genomic stability

1 reference

12 December 2020

Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours

1 reference

12 December 2020

Microsatellite instability in aberrant crypt foci from human colons

1 reference

12 December 2020

Transforming growth factor beta type II receptor gene mutations in adenomas from hereditary nonpolyposis colorectal cancer

1 reference

12 December 2020

Mixed epithelial polyps in association with hereditary non-polyposis colorectal cancer providing an alternative pathway of cancer histogenesis

1 reference

12 December 2020

Proapoptotic gene BAX is frequently mutated in hereditary nonpolyposis colorectal cancers but not in adenomas

1 reference

12 December 2020

Reciprocal relationship between the tumor suppressors p53 and BAX in primary colorectal cancers

1 reference

12 December 2020

Expression of Bcl-2 protein is decreased in colorectal adenocarcinomas with microsatellite instability

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.47.1.37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10861262 AND SRC:MED&resulttype=core&format=json

7 November 2019

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7 November 2019

PubMed publication ID

10861262

1 reference