Insulin signaling: implications for podocyte biology in diabetic kidney disease (Q35285585)

25415617

7 August 2017

title

Insulin signaling: implications for podocyte biology in diabetic kidney disease (English)

1 reference

7 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Alessia Fornoni

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

9 June 2020

publication date

1 January 2015

1 reference

25415617

Current Opinion in Nephrology and Hypertension

7 August 2017

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

9 June 2020

volume

24

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

9 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

104-110

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

Diabetic nephropathy: Is it time yet for routine kidney biopsy?

9 June 2020

cites work

1 reference

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Recent advances in our understanding of insulin signalling to the podocyte

12 July 2018

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Podocyte-specific GLUT4-deficient mice have fewer and larger podocytes and are protected from diabetic nephropathy.

12 July 2018

1 reference

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Susceptibility of podocytes to palmitic acid is regulated by stearoyl-CoA desaturases 1 and 2.

12 July 2018

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Cyclodextrin protects podocytes in diabetic kidney disease

12 July 2018

1 reference

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Insulin directly stimulates VEGF-A production in the glomerular podocyte

12 July 2018

1 reference

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Insulin increases glomerular filtration barrier permeability through dimerization of protein kinase G type Iα subunits

12 July 2018

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Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse.

12 July 2018

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Variation in APOL1 Contributes to Ancestry-Level Differences in HDLc-Kidney Function Association

12 July 2018

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Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking

12 July 2018

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Nutrient sensing, autophagy, and diabetic nephropathy

12 July 2018

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Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species

12 July 2018

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Podocytopathy in diabetes: a metabolic and endocrine disorder

12 July 2018

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Temporal Trends in the Prevalence of Diabetic Kidney Disease in the United States

12 July 2018

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Effects of insulin and high glucose on mobilization of slo1 BKCa channels in podocytes

12 July 2018

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Akt signalling in health and disease.

12 July 2018

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GLUT1 enhances mTOR activity independently of TSC2 and AMPK

12 July 2018

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mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice

12 July 2018

1 reference

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Role of mTOR in podocyte function and diabetic nephropathy in humans and mice

12 July 2018

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Glomerular-specific protein kinase C-β-induced insulin receptor substrate-1 dysfunction and insulin resistance in rat models of diabetes and obesity

12 July 2018

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Insulin signaling to the glomerular podocyte is critical for normal kidney function

12 July 2018

1 reference

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AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes.

12 July 2018

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Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Lipid phosphatase SHIP2 downregulates insulin signalling in podocytes

12 July 2018

1 reference

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Plasma membrane microdomains in aging and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Transgenic overexpression of GLUT1 in mouse glomeruli produces renal disease resembling diabetic glomerulosclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Exploring the caves: cavins, caveolins and caveolae.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

12 July 2018

1 reference

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Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Lipid-protein interactions along the slit diaphragm of podocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Cholesterol-regulated stress fiber formation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton

12 July 2018

1 reference

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Spectrum of renal diseases associated with extreme forms of insulin resistance

12 July 2018

1 reference

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Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Chronic exposure of human glomerular epithelial cells to high glucose concentration results in modulation of high-affinity glucose transporters expression

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Do membrane rafts contribute to human immunosenescence?

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Protection of the kidney by thiazolidinediones: an assessment from bench to bedside

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Critical nodes in signalling pathways: insights into insulin action

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

The human glomerular podocyte is a novel target for insulin action

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Defective insulin receptor activation and altered lipid rafts in Niemann-Pick type C disease hepatocytes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Thiazolidinediones-benefits on microvascular complications of type 2 diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Isoform-specific insulin receptor signaling involves different plasma membrane domains.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Insulin Signaling in Microdomains of the Plasma Membrane

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Sphingomyelinase activates GLUT4 translocation via a cholesterol-dependent mechanism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Cell biology of the glomerular podocyte

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Insulin signalling and the regulation of glucose and lipid metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Lipid rafts and signal transduction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

CD2AP is expressed with nephrin in developing podocytes and is found widely in mature kidney and elsewhere

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Signaling pathways in insulin action: molecular targets of insulin resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

NPHS2, encoding the glomerular protein podocin, is mutated in autosomal recessive steroid-resistant nephrotic syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Mutations in ACTN4, encoding alpha-actinin-4, cause familial focal segmental glomerulosclerosis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Caveolin-1 interacts with the insulin receptor and can differentially modulate insulin signaling in transfected Cos-7 cells and rat adipose cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Podocyte number predicts long-term urinary albumin excretion in Pima Indians with Type II diabetes and microalbuminuria

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Aldolase mediates the association of F-actin with the insulin-responsive glucose transporter GLUT4.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Caveolin is an activator of insulin receptor signaling

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Functional rafts in cell membranes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Podocyte loss and progressive glomerular injury in type II diabetes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Proteinuria, the Podocyte, and Insulin Resistance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Effect of a multifactorial intervention on mortality in type 2 diabetes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Podocin organizes ion channel-lipid supercomplexes: implications for mechanosensation at the slit diaphragm.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Rosiglitazone and cardiotoxicity--weighing the evidence

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Glucose-induced reactive oxygen species cause apoptosis of podocytes and podocyte depletion at the onset of diabetic nephropathy

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Statins prevent oxidized LDL-induced injury of glomerular podocytes by activating the phosphatidylinositol 3-kinase/AKT-signaling pathway

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Localization of the GLUT8 glucose transporter in murine kidney and regulation in vivo in nondiabetic and diabetic conditions

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Characterization of glucose uptake by cultured rat podocytes.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Decreasing incidence of severe diabetic microangiopathy in type 1 diabetes

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Glomerular endothelial fenestrae in vivo are not formed from caveolae

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Podocyte number in normotensive type 1 diabetic patients with albuminuria

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Microalbuminuria is associated with insulin resistance in nondiabetic subjects: the insulin resistance atherosclerosis study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Insulin resistance, hypertension and microalbuminuria in patients with type 2 (non-insulin-dependent) diabetes mellitus

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Insulin resistance and abnormal albumin excretion in non-diabetic first-degree relatives of patients with NIDDM.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Mechanosensitive channel activity and F-actin organization in cholesterol-depleted human leukaemia cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4386894

Insulin resistance in insulin-dependent diabetic patients with microalbuminuria

24 October 2018

1 reference

12 December 2020

Failure to phosphorylate AKT in podocytes from mice with early diabetic nephropathy promotes cell death

1 reference

12 December 2020

Insulin resistance precedes microalbuminuria in patients with insulin-dependent diabetes mellitus

1 reference

12 December 2020

Insulin resistance in family members of insulin-dependent diabetic patients with microalbuminuria

1 reference

12 December 2020

Nephrin Is Critical for the Action of Insulin on Human Glomerular Podocytes

1 reference

12 December 2020

AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

1 reference

12 December 2020

Getting a foothold in nephrotic syndrome

1 reference

12 December 2020

Hypertrophy and loss of podocytes in diabetic nephropathy

1 reference

12 December 2020

Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol

1 reference

12 December 2020

Endotoxin-mediated delayed islet graft function is associated with increased intra-islet cytokine production and islet cell apoptosis

1 reference

12 December 2020

Podocyte detachment and reduced glomerular capillary endothelial fenestration in human type 1 diabetic nephropathy

1 reference

12 December 2020

The acute effect of insulin on heart rate, blood pressure, plasma noradrenaline and urinary albumin excretion. The role of changes in blood glucose

1 reference

12 December 2020

Glomerular cell number in normal subjects and in type 1 diabetic patients

1 reference

12 December 2020

Insulin Resistance and Microalbuminuria: A Cross-Sectional, Case-Control Study of 158 Patients With Type 2 Diabetes and Different Degrees of Urinary Albumin Excretion

1 reference

12 December 2020

10.1097/MNH.0000000000000078

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json

9 June 2020

25415617

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25415617 AND SRC:MED&resulttype=core&format=json