Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form. (Q35236046)

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29 February 2020

title

Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form (English)

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29 February 2020

3

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29 February 2020

Laura Silvestri

10

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29 February 2020

author name string

Alessia Pagani

1

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29 February 2020

Maud Vieillevoye

2

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29 February 2020

Marco Rausa

4

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29 February 2020

Meriem Ladli

5

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29 February 2020

Catherine Lacombe

6

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29 February 2020

Patrick Mayeux

7

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29 February 2020

Frédérique Verdier

8

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29 February 2020

Clara Camaschella

9

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29 February 2020

publication date

30 January 2015

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29 February 2020

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29 February 2020

volume

100

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issue

4

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page(s)

458-465

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The second transferrin receptor regulates red blood cell production in mice

29 February 2020

cites work

1 reference

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The erythroid function of transferrin receptor 2 revealed by Tmprss6 inactivation in different models of transferrin receptor 2 knockout mice.

13 July 2018

1 reference

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In situ proximity ligation assays indicate that hemochromatosis proteins Hfe and transferrin receptor 2 (Tfr2) do not interact.

13 July 2018

1 reference

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The hemochromatosis proteins HFE, TfR2, and HJV form a membrane-associated protein complex for hepcidin regulation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Hereditary hemochromatosis and transferrin receptor 2

13 July 2018

1 reference

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A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis

13 July 2018

1 reference

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Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

13 July 2018

1 reference

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Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response

13 July 2018

1 reference

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Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis

13 July 2018

1 reference

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Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site

13 July 2018

1 reference

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The molecular mechanism of hepcidin-mediated ferroportin down-regulation

13 July 2018

1 reference

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Transferrin receptor 2: evidence for ligand-induced stabilization and redirection to a recycling pathway

13 July 2018

1 reference

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Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression

13 July 2018

1 reference

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Release of the soluble transferrin receptor is directly regulated by binding of its ligand ferritransferrin

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.

13 July 2018

1 reference

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Diferric transferrin regulates transferrin receptor 2 protein stability

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Soluble transferrin receptor for the evaluation of erythropoiesis and iron status

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Expression of transferrin receptor 2 in normal and neoplastic hematopoietic cells

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Regulation of expression of murine transferrin receptor 2.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Transferrin receptor 2-alpha supports cell growth both in iron-chelated cultured cells and in vivo

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Molecular cloning of transferrin receptor 2. A new member of the transferrin receptor-like family

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Redundant and distinct functions for dynamin-1 and dynamin-2 isoforms

13 July 2018

1 reference

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The trans-Golgi network: a late secretory sorting station

13 July 2018

1 reference

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Serum transferrin receptor is a truncated form of tissue receptor

13 July 2018

1 reference

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Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.

13 July 2018

1 reference

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Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis.

26 September 2018

1 reference

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Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues.

26 September 2018

1 reference

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Combined deletion of Hfe and transferrin receptor 2 in mice leads to marked dysregulation of hepcidin and iron overload.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380718

Hepcidin is decreased in TFR2 hemochromatosis

26 September 2018

1 reference

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Analyses for binding of the transferrin family of proteins to the transferrin receptor 2

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25637053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Serum transferrin receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25637053

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3324/HAEMATOL.2014.118521

1 reference

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29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25637053 AND SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

25637053

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25637053 AND SRC:MED&resulttype=core&format=json