Readers, writers, and erasers: chromatin as the whiteboard of heart disease (Q35234488)

7 August 2017

1 reference

title

Readers, writers, and erasers: chromatin as the whiteboard of heart disease (English)

1 reference

7 August 2017

1 reference

Thomas G Gillette

1

1 reference

7 August 2017

Joseph A Hill

series ordinal

2

1 reference

7 August 2017

language of work or name

1 reference

1 March 2015

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7 August 2017

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7 August 2017

volume

116

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7 August 2017

issue

7

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7 August 2017

page(s)

1245-1253

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Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload

7 August 2017

cites work

1 reference

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Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

13 July 2018

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A long noncoding RNA protects the heart from pathological hypertrophy

13 July 2018

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Molecular basis for substrate recognition by lysine methyltransferases and demethylases

13 July 2018

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The mechanisms behind the therapeutic activity of BET bromodomain inhibition

13 July 2018

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Targeting histone lysine demethylases - progress, challenges, and the future

13 July 2018

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Repressive histone methylation: a case study in deterministic versus stochastic gene regulation.

13 July 2018

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Suv39h1 protects from myocardial ischemia-reperfusion injury in diabetic rats

13 July 2018

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Targeting bromodomains: epigenetic readers of lysine acetylation

13 July 2018

1 reference

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Interpreting the language of histone and DNA modifications

13 July 2018

1 reference

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Regulation of acetylation of histone deacetylase 2 by p300/CBP-associated factor/histone deacetylase 5 in the development of cardiac hypertrophy

13 July 2018

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Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy.

13 July 2018

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Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes

13 July 2018

1 reference

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Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation

13 July 2018

1 reference

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Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy.

13 July 2018

1 reference

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BET acetyl-lysine binding proteins control pathological cardiac hypertrophy

13 July 2018

1 reference

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BET bromodomains mediate transcriptional pause release in heart failure

13 July 2018

1 reference

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Pathological ventricular remodeling: mechanisms: part 1 of 2

13 July 2018

1 reference

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Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells

13 July 2018

1 reference

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Nuclear CaMKII enhances histone H3 phosphorylation and remodels chromatin during cardiac hypertrophy.

13 July 2018

1 reference

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HDAC-dependent ventricular remodeling

13 July 2018

1 reference

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The emerging role of acetylation in the regulation of autophagy

13 July 2018

1 reference

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HDAC4 controls histone methylation in response to elevated cardiac load

13 July 2018

1 reference

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Histone acetyltransferases: Rising ancient counterparts to protein kinases

13 July 2018

1 reference

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Targeting epigenetic readers in cancer.

13 July 2018

1 reference

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Autophagy is impaired in cardiac ischemia-reperfusion injury

13 July 2018

1 reference

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Impaired autophagosome clearance contributes to cardiomyocyte death in ischemia/reperfusion injury

13 July 2018

1 reference

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Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.

13 July 2018

1 reference

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UTX, a Histone H3-Lysine 27 Demethylase, Acts as a Critical Switch to Activate the Cardiac Developmental Program

13 July 2018

1 reference

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PPARα-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathway.

13 July 2018

1 reference

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Distinct epigenomic features in end-stage failing human hearts

13 July 2018

1 reference

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Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation.

13 July 2018

1 reference

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Diet-induced Lethality Due to Deletion of the Hdac3 Gene in Heart and Skeletal Muscle

13 July 2018

1 reference

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The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice

13 July 2018

1 reference

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Readers of histone modifications

13 July 2018

1 reference

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Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy

13 July 2018

1 reference

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Chromatin remodeling in cardiovascular development and physiology

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

DOT1L regulates dystrophin expression and is critical for cardiac function

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Targeting Inflammation in Heart Failure with Histone Deacetylase Inhibitors

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Silent information regulator 1 protects the heart from ischemia/reperfusion

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Benefits of histone deacetylase inhibitors for acute brain injury: a systematic review of animal studies.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Chromatin regulation by Brg1 underlies heart muscle development and disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Brd4 engagement from chromatin targeting to transcriptional regulation: selective contact with acetylated histone H3 and H4.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Genome-wide mapping of HATs and HDACs reveals distinct functions in active and inactive genes

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Inhibition of class I histone deacetylase with an apicidin derivative prevents cardiac hypertrophy and failure

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Histone deacetylase inhibition reduces myocardial ischemia-reperfusion injury in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

13 July 2018

1 reference

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The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Sirtuins in mammals: insights into their biological function

13 July 2018

1 reference

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Histone acetyltransferase complexes: one size doesn't fit all

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein

13 July 2018

1 reference

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Histone demethylation mediated by the nuclear amine oxidase homolog LSD1

13 July 2018

1 reference

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Polybromo protein BAF180 functions in mammalian cardiac chamber maturation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Baf60c is essential for function of BAF chromatin remodelling complexes in heart development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation

13 July 2018

1 reference

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ACETYLATION AND METHYLATION OF HISTONES AND THEIR POSSIBLE ROLE IN THE REGULATION OF RNA SYNTHESIS

13 July 2018

1 reference

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Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

The transcriptional co-activators CREB-binding protein (CBP) and p300 play a critical role in cardiac hypertrophy that is dependent on their histone acetyltransferase activity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Regulation of chromatin structure by site-specific histone H3 methyltransferases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Methylation of histone H3 at lysine 4 is highly conserved and correlates with transcriptionally active nuclei in Tetrahymena

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

jumonji gene is essential for the neurulation and cardiac development of mouse embryos with a C3H/He background

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

The TAF(II)250 subunit of TFIID has histone acetyltransferase activity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

The CBP co-activator is a histone acetyltransferase

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

The major cytoplasmic histone acetyltransferase in yeast: links to chromatin replication and histone metabolism

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Control of histone H3 phosphorylation by CaMKIIδ in response to haemodynamic cardiac stress

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Class I HDAC inhibition stimulates cardiac protein SUMOylation through a post-translational mechanism.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Inhibition of histone deacetylation blocks cardiac hypertrophy induced by angiotensin II infusion and aortic banding

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Impact of beta-myosin heavy chain expression on cardiac function during stress

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Dystrophin upregulation in pressure-overloaded cardiac hypertrophy in rats

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Small amounts of alpha-myosin heavy chain isoform expression significantly increase power output of rat cardiac myocyte fragments

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Metabolic gene expression in fetal and failing human heart

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4380191

Dystrophin-deficient myocardium is vulnerable to pressure overload in vivo

26 September 2018

1 reference

12 December 2020

Inhibition of histone deacetylase on ventricular remodeling in infarcted rats

1 reference

12 December 2020

Response to Crozatier and Ventura-Clapier

1 reference

12 December 2020

The Swi2/Snf2 bromodomain is important for the full binding and remodeling activity of the SWI/SNF complex on H3- and H4-acetylated nucleosomes

1 reference

12 December 2020

10.1161/CIRCRESAHA.116.303630

Identifiers

DOI

1 reference

7 August 2017

1 reference

7 August 2017

1 reference