Predicting the functional impact of protein mutations: application to cancer genomics (Q35224321)

7 August 2017

title

Predicting the functional impact of protein mutations: application to cancer genomics (English)

1 reference

7 August 2017

3

Chris Sander

1 reference

7 August 2017

2

Yevgeniy Antipin

1 reference

7 August 2017

1

Boris Reva

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21727090

6 December 2024

language of work or name

English

0 references

publication date

3 July 2011

1 reference

full work available at URL

7 August 2017

https://academic.oup.com/nar/article-pdf/39/17/e118/16776369/gkr407.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21727090

https://europepmc.org/articles/PMC3177186

6 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21727090

https://europepmc.org/articles/PMC3177186?pdf=render

6 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21727090

http://academic.oup.com/nar/article-pdf/39/17/e118/16776369/gkr407.pdf

6 December 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1093/NAR/GKR407

6 December 2024

published in

Nucleic Acids Research

1 reference

7 August 2017

volume

39

1 reference

7 August 2017

issue

17

1 reference

7 August 2017

page(s)

e118

1 reference

Creative Commons Attribution-NonCommercial 3.0 Unported

7 August 2017

copyright license

start time

7 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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A CDKN2A mutation in familial melanoma that abrogates binding of p16INK4a to CDK4 but not CDK6

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Patterns of somatic mutation in human cancer genomes

13 July 2018

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Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

13 July 2018

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Distinguishing cancer-associated missense mutations from common polymorphisms

13 July 2018

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CancerGenes: a gene selection resource for cancer genome projects

13 July 2018

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The consensus coding sequences of human breast and colorectal cancers

13 July 2018

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Catalytic inactivation of human phospholipase D2 by a naturally occurring Gly901Asp mutation

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177186

Predicting the effects of amino acid substitutions on protein function

13 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3177186

Cellular localization of 17 natural mutant variants of ALADIN protein in triple A syndrome - shedding light on an unexpected splice mutation

13 July 2018

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The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme's stability and conformational transitions linked to Na binding

13 July 2018

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Physicochemical constraint violation by missense substitutions mediates impairment of protein function and disease severity

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Switch-of-Function Mutants Based on Morphology Classification of Ras Superfamily Small GTPases

13 July 2018

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Human non-synonymous SNPs: server and survey

13 July 2018

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13 July 2018

The Hallmarks of Cancer

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13 July 2018

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An evolutionary trace method defines binding surfaces common to protein families

13 July 2018

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A method to predict functional residues in proteins

13 July 2018

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13 July 2018

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Computational characterization of structural role of the non-active site mutation M36I of human immunodeficiency virus type 1 protease

13 July 2018

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Missense mutation in the N-acetylglucosamine-1-phosphotransferase gene (GNPTA) in a patient with mucolipidosis II induces changes in the size and cellular distribution of GNPTG.

26 September 2018

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26 September 2018

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Mutation of active site residues in the chitin-binding domain ChBDChiA1 from chitinase A1 of Bacillus circulans alters substrate specificity: use of a green fluorescent protein binding assay

26 September 2018

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26 September 2018

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Human factor VII deficiency caused by S339C mutation located adjacent to the specificity pocket of the catalytic domain

26 September 2018

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Effect of single active-site cleft mutation on product specificity in a thermostable bacterial cellulase

26 September 2018

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Effects of core mutations on the folding of a beta-sheet protein: implications for backbone organization in the I-state

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21727090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21727090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of mutations on the thermodynamics of a protein folding reaction: implications for the mechanism of formation of the intermediate and transition states

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21727090

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKR407

1 reference

7 August 2017

1 reference

7 August 2017

1 reference