PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis (Q35217174)

7 August 2017

title

PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis (English)

1 reference

7 August 2017

Nina Ilic

1

1 reference

7 August 2017

Tamara Utermark

series ordinal

2

1 reference

7 August 2017

Hans R Widlund

series ordinal

3

1 reference

7 August 2017

Thomas M Roberts

series ordinal

4

1 reference

7 August 2017

language of work or name

English

0 references

publication date

29 August 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

7 August 2017

published in

1 reference

7 August 2017

volume

108

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7 August 2017

issue

37

1 reference

7 August 2017

page(s)

E699-708

1 reference

MYC regulation of a "poor-prognosis" metastatic cancer cell state

7 August 2017

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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An essential E box in the promoter of the gene encoding the mRNA cap-binding protein (eukaryotic initiation factor 4E) is a target for activation by c-myc

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

13 July 2018

1 reference

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First-line gefitinib in patients with advanced non-small-cell lung cancer harboring somatic EGFR mutations

13 July 2018

1 reference

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The translation factor eIF-4E promotes tumor formation and cooperates with c-Myc in lymphomagenesis

26 September 2018

1 reference

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26 September 2018

1 reference

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Drosophila myc regulates cellular growth during development.

26 September 2018

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Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

26 September 2018

1 reference

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Detection of eIF4E gene amplification in breast cancer by competitive PCR.

26 September 2018

1 reference

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Human mammary epithelial cell transformation through the activation of phosphatidylinositol 3-kinase

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21876152

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1108237108

1 reference

7 August 2017

0 references

1 reference

7 August 2017

1 reference