The distinct role of mGlu1 receptors in post-ischemic neuronal death (Q35216446)

7 August 2017

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title

The distinct role of mGlu1 receptors in post-ischemic neuronal death (English)

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7 August 2017

author name string

Domenico E Pellegrini-Giampietro

series ordinal

1

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7 August 2017

publication date

1 September 2003

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Trends in Pharmacological Sciences

7 August 2017

published in

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7 August 2017

volume

24

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7 August 2017

issue

9

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7 August 2017

page(s)

461-470

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Molecular determinants of metabotropic glutamate receptor signaling.

7 August 2017

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Antagonists for group I mGluRs attenuate excitotoxic neuronal death in cortical cultures

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Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, ( )-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 r

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The inhibitory mGluR agonist, S-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death

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1-Aminoindan-1,5-dicarboxylic acid and (S)-( )-2-(3'-carboxybicyclo[1.1.1] pentyl)-glycine, two mGlu1 receptor-preferring antagonists, reduce neuronal death in in vitro and in vivo models of cerebral ischaemia

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7 January 2021

Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro

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7 January 2021

Activation of mGlu1 but not mGlu5 metabotropic glutamate receptors contributes to postischemic neuronal injury in vitro and in vivo

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7 January 2021

The novel and systemically active metabotropic glutamate 1 (mGlu1) receptor antagonist 3-MATIDA reduces post-ischemic neuronal death

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Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time-course and mechanisms

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The mGlu receptor ligand (S)-4C3HPG protects neurons after global ischaemia in gerbils

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(S)-4C3HPG reduces infarct size after focal cerebral ischemia.

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Selective blockade of metabotropic glutamate receptor subtype 5 is neuroprotective

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Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil

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7 January 2021

Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia

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7 January 2021

Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

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Control of calcium oscillations by phosphorylation of metabotropic glutamate receptors

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Metabotropic glutamate receptors 1 and 5 differentially regulate CA1 pyramidal cell function.

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7 January 2021

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7 January 2021

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7 January 2021

Metabotropic glutamate 1 (mGlu1) receptor antagonists enhance GABAergic neurotransmission: a mechanism for the attenuation of post-ischemic injury and epileptiform activity?

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7 January 2021

Beta-amyloid-induced apoptosis of cerebellar granule cells and cortical neurons: exacerbation by selective inhibition of group I metabotropic glutamate receptors

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7 January 2021

Selective blockade of mGlu5 metabotropic glutamate receptors is protective against methamphetamine neurotoxicity.

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7 January 2021

Exacerbation of neuronal cell death by activation of group I metabotropic glutamate receptors: role of NMDA receptors and arachidonic acid release.

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7 January 2021

Interactions between ionotropic and metabotropic glutamate receptors regulate cAMP response element-binding protein phosphorylation in cultured striatal neurons

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Increased expression of neuronal nitric oxide synthase spliced variants in reactive astrocytes of amyotrophic lateral sclerosis human spinal cord

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The metabotropic glutamate receptor mGlu5 controls the onset of developmental apoptosis in cultured cerebellar neurons

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The metabotropic glutamate receptor (mGluR1 alpha) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction.

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7 January 2021

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Localization of mGluR1a-like immunoreactivity and mGluR5-like immunoreactivity in identified populations of striatal neurons

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7 January 2021

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Synthesis and pharmacological characterisation of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists

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A novel, competitive mGlu(5) receptor antagonist (LY344545) blocks DHPG-induced potentiation of NMDA responses but not the induction of LTP in rat hippocampal slices

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Reduced stress-induced hyperthermia in mGluR5 knockout mice

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Distribution and synaptic localisation of the metabotropic glutamate receptor 4 (mGluR4) in the rodent CNS

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7 January 2021

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Identifiers

DOI

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7 August 2017

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