Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools (Q35209364)

7 August 2017

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title

Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools (English)

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7 August 2017

Richard Greil

1

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7 August 2017

Gabriele Anether

series ordinal

2

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7 August 2017

Karin Johrer

series ordinal

3

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7 August 2017

Inge Tinhofer

series ordinal

4

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7 August 2017

publication date

1 September 2003

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Journal of Leukocyte Biology

7 August 2017

published in

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7 August 2017

volume

74

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7 August 2017

issue

3

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7 August 2017

page(s)

311-330

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Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease

7 August 2017

cites work

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Structure and function of Fas/Fas ligand

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The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

21 January 2018

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Two CD95 (APO-1/Fas) signaling pathways

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Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand

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Human autoimmune lymphoproliferative syndrome, a defect in the apoptosis-inducing Fas receptor: a lesson from the mouse model

21 January 2018

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Characterization of the in vivo function of TNF-alpha-related apoptosis-inducing ligand, TRAIL/Apo2L, using TRAIL/Apo2L gene-deficient mice

21 January 2018

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

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Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

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T cell-specific FADD-deficient mice: FADD is required for early T cell development

21 January 2018

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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Generation and characterization of Smac/DIABLO-deficient mice.

21 January 2018

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Characterization of XIAP-deficient mice

21 January 2018

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Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

21 January 2018

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Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

21 January 2018

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IAP family proteins--suppressors of apoptosis

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

21 January 2018

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Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

21 January 2018

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Activation of caspase-8 in drug-induced apoptosis of B-lymphoid cells is independent of CD95/Fas receptor-ligand interaction and occurs downstream of caspase-3.

21 January 2018

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Caspase-9 processing by caspase-3 via a feedback amplification loop in vivo

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Maximal Proliferation of Cytotoxic T Lymphocytes Requires Reverse Signaling through Fas Ligand

21 January 2018

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Identification and characterization of a new member of the TNF family that induces apoptosis

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Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

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Safety and antitumor activity of recombinant soluble Apo2 ligand

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The receptor for the cytotoxic ligand TRAIL

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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

21 January 2018

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FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

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Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II

21 January 2018

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TRAIL receptor-2 signals apoptosis through FADD and caspase-8

21 January 2018

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The novel receptor TRAIL-R4 induces NF-kappaB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain

21 January 2018

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Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.

21 January 2018

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In vitro susceptibility to TRAIL-induced apoptosis of acute leukemia cells in the context of TRAIL receptor gene expression and constitutive NF-kappa B activity.

21 January 2018

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Transfection of caspase-3 in the caspase-3-deficient Hodgkin's disease cell line, KMH2, results in enhanced sensitivity to CD95-, TRAIL-, and ARA-C-induced apoptosis

21 January 2018

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Induction of a TRAIL-mediated suicide program by interferon alpha in primary effusion lymphoma

21 January 2018

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Involvement of TRAIL/TRAIL-R interaction in IFN-alpha-induced apoptosis of Daudi B lymphoma cells.

21 January 2018

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Apo2L/TRAIL and Bcl-2-related proteins regulate type I interferon-induced apoptosis in multiple myeloma

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TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications

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CD95's deadly mission in the immune system

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A membrane-bound Fas decoy receptor expressed by human thymocytes

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A role for Fas in negative selection of thymocytes in vivo

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Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas.

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The dual functions of fas ligand in the regulation of peripheral CD8 and CD4 T cells

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Fas ligand mediates activation-induced cell death in human T lymphocytes

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Surface expression of TRAIL/Apo-2 ligand in activated mouse T and B cells

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Tumor necrosis factor-related apoptosis-inducing ligand in T cell development: sensitivity of human thymocytes

21 January 2018

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FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis

21 January 2018

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Death-receptor contribution to the germinal-center reaction.

21 January 2018

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Fas is required for clonal selection in germinal centers and the subsequent establishment of the memory B cell repertoire

21 January 2018

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Fas-L up-regulation by highly malignant myeloma plasma cells: role in the pathogenesis of anemia and disease progression.

21 January 2018

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Fas ligand expression in Hodgkin lymphoma.

21 January 2018

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CD95 ligand (CD95L) in normal human lymphoid tissues: a subset of plasma cells are prominent producers of CD95L.

21 January 2018

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Negative regulation of erythroblast maturation by Fas-L( )/TRAIL( ) highly malignant plasma cells: a major pathogenetic mechanism of anemia in multiple myeloma.

21 January 2018

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TRAIL (Apo2L) suppresses growth of primary human leukemia and myelodysplasia progenitors

21 January 2018

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Mice defective in two apoptosis pathways in the myeloid lineage develop acute myeloblastic leukemia

21 January 2018

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Human dendritic cells mediate cellular apoptosis via tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)

21 January 2018

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Critical contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to apoptosis of human CD4 T cells in HIV-1-infected hu-PBL-NOD-SCID mice

21 January 2018

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Measles virus induces functional TRAIL production by human dendritic cells

21 January 2018

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Spontaneous development of plasmacytoid tumors in mice with defective Fas-Fas ligand interactions

21 January 2018

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The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

21 January 2018

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A tumor-suppressor function for Fas (CD95) revealed in T cell-deficient mice

21 January 2018

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An inherited disorder of lymphocyte apoptosis: the autoimmune lymphoproliferative syndrome

21 January 2018

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Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia.

21 January 2018

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Pathological findings in human autoimmune lymphoproliferative syndrome

21 January 2018

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Fas gene mutations in the Canale-Smith syndrome, an inherited lymphoproliferative disorder associated with autoimmunity

21 January 2018

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The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis

21 January 2018

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The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

21 January 2018

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Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape

21 January 2018

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Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction

21 January 2018

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Gene transfer of Fas ligand induces tumor regression in vivo

21 January 2018

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Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice

21 January 2018

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Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

21 January 2018

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

21 January 2018

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The involvement of TNF-alpha-related apoptosis-inducing ligand in the enhanced cytotoxicity of IFN-beta-stimulated human dendritic cells to tumor cells.

21 January 2018

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Mutation analysis of the FAS and TNFR apoptotic cascade genes in hematological malignancies.

21 January 2018

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Mutation analysis of CD95 (APO-1/Fas) in childhood B-lineage acute lymphoblastic leukaemia.

21 January 2018

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Loss of Fas (CD95/APO-1) regulatory function is an important step in early MALT-type lymphoma development

21 January 2018

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Fas/Apo-1 (CD95)-mediated and CD95-independent apoptosis of malignant plasma cells

21 January 2018

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

21 January 2018

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Frequent nuclear localization of ICAD and cytoplasmic co-expression of caspase-8 and caspase-3 in human lymphomas

21 January 2018

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Lethal effect of the anti-Fas antibody in mice

21 January 2018

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Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin.

21 January 2018

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Clonal variability in CD95 expression is the major determinant in Fas-medicated, but not chemotherapy-medicated apoptosis in the RPMI 8226 multiple myeloma cell line

21 January 2018

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fas-mediated lysis of chronic lymphocytic leukaemia cells: role of type I versus type II cytokines and autologous fasL-expressing T cells.

21 January 2018

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Interleukin-15 as a potential costimulatory cytokine in CD154 gene therapy of chronic lymphocytic leukemia

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Cellular origin of human B-cell lymphomas.

21 January 2018

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Bryostatin and CD40-ligand enhance apoptosis resistance and induce expression of cell survival genes in B-cell chronic lymphocytic leukaemia.

21 January 2018

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What is the real role of CD40 in cancer immunotherapy?

21 January 2018

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A novel murine anti-human Fas mAb which mitigates lymphadenopathy without hepatotoxicity.

21 January 2018

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

21 January 2018

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Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

21 January 2018

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Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

21 January 2018

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Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells

21 January 2018

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TRAIL enhances thymidine kinase/ganciclovir gene therapy of neuroblastoma cells

21 January 2018

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Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis

21 January 2018

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Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

21 January 2018

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Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ

21 January 2018

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The triterpenoid CDDO induces apoptosis in refractory CLL B cells

21 January 2018

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Acute rejection of murine bone marrow allografts by natural killer cells and T cells. Differences in kinetics and target antigens recognized

21 January 2018

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Graft-versus-host-disease-associated lymphoid hypoplasia and B cell dysfunction is dependent upon donor T cell-mediated Fas-ligand function, but not perforin function

21 January 2018

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The role of cell-mediated cytotoxicity in acute GVHD after MHC-matched allogeneic bone marrow transplantation in mice

21 January 2018

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Perforin/granzyme-dependent and independent mechanisms are both important for the development of graft-versus-host disease after murine bone marrow transplantation

21 January 2018

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Decreased tumor surveillance in perforin-deficient mice

21 January 2018

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A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease

21 January 2018

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Cytotoxic T cells deficient in both functional fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease

21 January 2018

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T cells require TRAIL for optimal graft-versus-tumor activity

21 January 2018

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Control of apoptosis and mitotic spindle checkpoint by survivin

21 January 2018

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Direct in vivo transfection of antisense Fas-ligand reduces tumor growth and invasion

21 January 2018

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Chronic restraint stress promotes lymphocyte apoptosis by modulating CD95 expression

21 January 2018

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Human brain-cell death induced by tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL)

21 January 2018

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Survivin is expressed on CD40 stimulation and interfaces proliferation and apoptosis in B-cell chronic lymphocytic leukemia

21 January 2018

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Role of the CD40 and CD95 (APO-1/Fas) antigens in the apoptosis of human B-cell malignancies

21 January 2018

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Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by selective up-regulation of TRAIL-R1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1189/JLB.0802416

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7 August 2017

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