Proinsulin-a pathogenic autoantigen in type 1 diabetes. (Q35171958)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

review article

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title

Proinsulin-a pathogenic autoantigen in type 1 diabetes (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

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1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

author name string

Stuart I Mannering

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

Leonard C Harrison

series ordinal

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

publication date

1 June 2003

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

volume

2

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5 November 2019

issue

4

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5 November 2019

page(s)

204-210

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5 November 2019

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7 January 2021

Self-antigen-presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs

1 reference

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7 January 2021

New aspects of proinsulin physiology and pathophysiology

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Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

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7 January 2021

Early expression of antiinsulin autoantibodies of humans and the NOD mouse: evidence for early determination of subsequent diabetes

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7 January 2021

Autoantibodies to insulin and to proinsulin in type 1 diabetic patients and in at-risk probands differentiate only little between both antigens

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7 January 2021

Proinsulin autoantibodies are more closely associated with type 1 (insulin-dependent) diabetes mellitus than insulin autoantibodies

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Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age

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7 January 2021

Humoral and cellular immune responses to proinsulin in adults with newly diagnosed type 1 diabetes

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7 January 2021

Insulin autoantibodies: more specific than proinsulin autoantibodies for prediction of type 1 diabetes

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7 January 2021

Proinsulin-specific autoantibodies are relatively infrequent in young offspring with pre-type 1 diabetes

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7 January 2021

Cellular immune responses against proinsulin: no evidence for enhanced reactivity in individuals with IDDM

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7 January 2021

T-cell response to proinsulin and insulin in type 1 and pretype 1 diabetes

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7 January 2021

Altered immune response to insulin in newly diagnosed compared to insulin-treated diabetic patients and healthy control subjects

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Insulin-specific T cells are a predominant component of islet infiltrates in pre-diabetic NOD mice

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7 January 2021

Evidence that a peptide spanning the B-C junction of proinsulin is an early Autoantigen epitope in the pathogenesis of type 1 diabetes

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7 January 2021

T cell autoreactivity to proinsulin epitopes in diabetic patients and healthy subjects

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7 January 2021

T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin

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7 January 2021

T Cell Recognition of Human Pre-Proinsulin Peptides Depends on the Polymorphism at HLA DQ Locus: A Study Using HLA DQ8 and DQ6 Transgenic Mice

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7 January 2021

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7 January 2021

Predominantly recognized proinsulin T helper cell epitopes in individuals with and without islet cell autoimmunity

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7 January 2021

Identification of an MHC class I-restricted autoantigen in type 1 diabetes by screening an organ-specific cDNA library.

1 reference

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7 January 2021

Epitope specificity, cytokine production profile and diabetogenic activity of insulin-specific T cell clones isolated from NOD mice

1 reference

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7 January 2021

Disabling an integral CTL epitope allows suppression of autoimmune diabetes by intranasal proinsulin peptide

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Transfer of diabetes type 1 by bone-marrow transplantation

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Is type 1 diabetes transmissible by bone marrow allograft?

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Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

1 reference

https://api.crossref.org/works/10.1016/S1568-9972(03)50009-0

7 January 2021

The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes

1 reference

https://api.crossref.org/works/10.1016/S1568-9972(03)50009-0

7 January 2021

Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes

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7 January 2021

Antigen-specific therapy for autoimmune disease

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7 January 2021

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

1 reference

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7 January 2021

T cell response to preproinsulin I and II in the nonobese diabetic mouse

1 reference

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7 January 2021

Insulin-specific tolerance in diabetes

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7 January 2021

10.1016/S1568-9972(03)00009-0

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12848947 AND SRC:MED&resulttype=core&format=json

5 November 2019

1 reference