In Vitro and In Vivo Pre-Clinical Analysis of a F(ab')(2) Fragment of Panitumumab for Molecular Imaging and Therapy of HER1 Positive Cancers (Q35162293)

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English	In Vitro and In Vivo Pre-Clinical Analysis of a F(ab')(2) Fragment of Panitumumab for Molecular Imaging and Therapy of HER1 Positive Cancers	scientific article

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21845232 AND SRC:MED&resulttype=core&format=json

10 February 2020

In Vitro and In Vivo Pre-Clinical Analysis of a F(ab')(2) Fragment of Panitumumab for Molecular Imaging and Therapy of HER1 Positive Cancers (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21845232 AND SRC:MED&resulttype=core&format=json

10 February 2020

3

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10 February 2020

author name string

Karen J Wong

1

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10 February 2020

Kwamena E Baidoo

2

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10 February 2020

Kayhan Garmestani

4

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10 February 2020

Martin W Brechbiel

5

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10 February 2020

Diane E Milenic

6

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10 February 2020

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1 June 2011

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10 February 2020

EJNMMI Research

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10 February 2020

1

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10 February 2020

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21845232 AND SRC:MED&resulttype=core&format=json

10 February 2020

HER1-targeted 86Y-panitumumab possesses superior targeting characteristics than 86Y-cetuximab for PET imaging of human malignant mesothelioma tumors xenografts

1 reference

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13 July 2018

Improved Speciation Characteristics of PEGylated Indocyanine Green-Labeled Panitumumab: Revisiting the Solution and Spectroscopic Properties of a Near-Infrared Emitting anti-HER1 Antibody for Optical Imaging of Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Epidermal Growth Factor Receptor–Targeted Radioimmunotherapy of Human Head and Neck Cancer Xenografts Using 90Y-Labeled Fully Human Antibody Panitumumab

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Positive progress in immunoPET--not just a coincidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Preparation, biological evaluation, and pharmacokinetics of the human anti-HER1 monoclonal antibody panitumumab labeled with 86Y for quantitative PET of carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Antibody vectors for imaging

1 reference

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13 July 2018

MONICA: a compact, portable dual gamma camera system for mouse whole-body imaging.

1 reference

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13 July 2018

PET imaging of HER1-expressing xenografts in mice with 86Y-CHX-A''-DTPA-cetuximab.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Repeated Intraperitoneal alpha-Radioimmunotherapy of Ovarian Cancer in Mice

1 reference

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13 July 2018

Preclinical evaluation of a monoclonal antibody targeting the epidermal growth factor receptor as a radioimmunodiagnostic and radioimmunotherapeutic agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

PET of EGFR antibody distribution in head and neck squamous cell carcinoma models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Antibodies and antimatter: the resurgence of immuno-PET.

1 reference

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13 July 2018

Cetuximab: preclinical evaluation of a monoclonal antibody targeting EGFR for radioimmunodiagnostic and radioimmunotherapeutic applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Imaging of HER-2 overexpression in tumors for guiding therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Design, synthesis, and characterization of a dual modality positron emission tomography and fluorescence imaging agent for monoclonal antibody tumor-targeted imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

FDA drug approval summary: panitumumab (Vectibix).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Biodistribution and planar gamma camera imaging of (123)I- and (131)I-labeled F(ab')(2) and Fab fragments of monoclonal antibody 14C5 in nude mice bearing an A549 lung tumor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Elimination mechanisms of therapeutic monoclonal antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Imaging the pharmacodynamics of HER2 degradation in response to Hsp90 inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Protein measurement with the Folin phenol reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Radioimmunotherapy: designer molecules to potentiate effective therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Transport of molecules in the tumor interstitium: a review

1 reference

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13 July 2018

Detection of colorectal carcinoma by emission-computerized tomography after injection of 123I-labeled Fab or F(ab')2 fragments from monoclonal anti-carcinoembryonic antigen antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

The development of new radiopharmaceuticals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Construction, binding properties, metabolism, and tumor targeting of a single-chain Fv derived from the pancarcinoma monoclonal antibody CC49.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3155408

13 July 2018

Stable, genetically engineered F(ab')(2) fragments of chimeric TNT-3 expressed in mammalian cells

1 reference

https://api.crossref.org/works/10.1186/2191-219X-1-1

21 January 2018

Human/murine chimeric 81C6 F(ab')(2) fragment: preclinical evaluation of a potential construct for the targeted radiotherapy of malignant glioma

1 reference

https://api.crossref.org/works/10.1186/2191-219X-1-1

21 January 2018

Radioimmunotherapy of human colon carcinoma xenografts using a 213Bi-labeled domain-deleted humanized monoclonal antibody

1 reference

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21 January 2018

In vivo comparison of macrocyclic and acyclic ligands for radiolabeling of monoclonal antibodies with 177Lu for radioimmunotherapeutic applications

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21 January 2018

In vivo evaluation of bismuth-labeled monoclonal antibody comparing DTPA-derived bifunctional chelates

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21 January 2018

In vivo evaluation of 177Lu- and 67/64Cu-labeled recombinant fragments of antibody chCE7 for radioimmunotherapy and PET imaging of L1-CAM-positive tumors.

1 reference

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21 January 2018

Radiation dosimetry of 99mTc-labeled C225 in patients with squamous cell carcinoma of the head and neck.

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27 September 2018

99mTc-labeled divalent and tetravalent CC49 single-chain Fv's: novel imaging agents for rapid in vivo localization of human colon carcinoma

1 reference

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27 September 2018

Microautoradiographic analysis of the normal organ distribution of radioiodinated single-chain Fv and other immunoglobulin forms.

1 reference

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27 September 2018

Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved radioimaging and tumor localization with monoclonal F(ab')2

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Different behaviour of mouse-human chimeric antibody F(ab')2 fragments of IgG1, IgG2 and IgG4 sub-classin vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phase I and imaging trial of indium 111-labeled anti-epidermal growth factor receptor monoclonal antibody 225 in patients with squamous cell lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of methods for the generation of immunoreactive fragments of a monoclonal antibody (B72.3) reactive with human carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of primate antibody responses to administered murine monoclonal immunoglobulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating immune complexes in cancer patients receiving goat radiolocalizing antibodies to carcinoembryonic antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spectrophotometric method for the determination of a bifunctional DTPA ligand in DTPA-monoclonal antibody conjugates

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stereochemical influence on the stability of radio-metal complexes in vivo. Synthesis and evaluation of the four stereoisomers of 2-(p-nitrobenzyl)-trans-CyDTPA

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiolocalization of human mammary tumors in athymic mice by a monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Avidity-mediated enhancement of in vivo tumor targeting by single-chain Fv dimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new and convenient method for purification of 86Y using a Sr(II) selective resin and comparison of biodistribution of 86Y and 111In labeled Herceptin

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Separation of univalent fragments from the bivalent rabbit antibody molecule by reduction of disulfide bonds

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of monoclonal immunoglobulin G1, F(ab')2, and Fab' in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High affinity restricts the localization and tumor penetration of single-chain fv antibody molecules

1 reference

https://pubmed.ncbi.nlm.nih.gov/21845232

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/2191-219X-1-1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21845232 AND SRC:MED&resulttype=core&format=json

10 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21845232 AND SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21845232 AND SRC:MED&resulttype=core&format=json

10 February 2020

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