Flip-flop pharmacokinetics--delivering a reversal of disposition: challenges and opportunities during drug development (Q35153417)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21837267 AND SRC:MED&resulttype=core&format=json

10 February 2020

review article

1 reference

title

Flip-flop pharmacokinetics--delivering a reversal of disposition: challenges and opportunities during drug development (English)

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10 February 2020

1 reference

1

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10 February 2020

Casey L. Sayre

3

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10 February 2020

M Laird Forrest

4

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10 February 2020

author name string

Connie M Remsberg

2

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10 February 2020

Neal M Davies

5

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10 February 2020

publication date

1 May 2011

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10 February 2020

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10 February 2020

volume

2

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10 February 2020

issue

5

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10 February 2020

page(s)

643-672

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Influence of the injection site on the pharmacokinetics of amoxicillin after intramuscular administration of a conventional and a long-acting formulation in sheep

10 February 2020

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Preclinical evaluation of pharmacokinetic-pharmacodynamic rationale for oral CR metformin formulation

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Effect of a high-fat meal on thalidomide pharmacokinetics and the relative bioavailability of oral formulations in healthy men and women

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27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Single-dose oral pharmacokinetics of three formulations of thalidomide in healthy male volunteers

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Cubic spline functions and polynomials for calculation of absorption rate.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Pharmacokinetics of oxytetracycline after intramuscular administration with lidocaine in sheep, comparison with a conventional formulation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Systemic absorption and block after epidural injection of ropivacaine in healthy volunteers

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Pharmacokinetics of amoxicillin/clavulanic acid combination after intravenous and oral administration in goats.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Population pharmacokinetics of theophylline. III. Premarketing study for a once-daily administered preparation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Pharmacokinetics of enrofloxacin after single intravenous, intramuscular and subcutaneous injections in lactating cows.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Bioavailability of controlled release carbamazepine estimated by mixed effect modelling

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Simplified methods for the evaluation of the parameters of the time course of plasma concentration in the one-compartment body model with first-order invasion and first-order drug elimination including methods for ascertaining when such rate constan

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Pharmacokinetic studies in volunteers of intravenous and oral cis (Z)-flupentixol and intramuscular cis (Z)-flupentixol decanoate in Viscoleo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

[Pharmacokinetics of a new antitumor antibiotic, neothramycin, after intrapleural administration]

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Pharmacokinetics and protein binding of trichothecene mycotoxins, T-2 toxin and HT-2 toxin, in dogs

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3152312

Evidence of a flip-flop phenomenon in acamprosate pharmacokinetics: an in vivo study in rats

27 September 2018

1 reference

12 December 2020

Pharmacokinetics of sodium and trihydrate amoxicillin in sheep after intravenous and intramuscular administration

1 reference

12 December 2020

Metabolism of 14C-moxisylyte after percutaneous application in hairless rat

1 reference

12 December 2020

Pharmacokinetics and penetration of danofloxacin from the blood into the milk of cows

1 reference

12 December 2020

The pharmacokinetics and metabolism of 14C/13C-labeled ortho-phenylphenol formation following dermal application to human volunteers

1 reference

12 December 2020

Pharmacokinetics of thalidomide in an elderly prostate cancer population

1 reference

12 December 2020

Pharmacokinetics and leukocyte responses of recombinant human interleukin-10

1 reference

12 December 2020

KINETIC ANALYSIS OF BLOOD LEVELS AND URINARY EXCRETION IN THE ABSORPTIVE PHASE AFTER SINGLE DOSES OF DRUG

1 reference

12 December 2020

Can tobramycin inhalation be improved with a jet nebulizer?

1 reference

12 December 2020

Pharmacokinetics of indomethacin in poultry

1 reference

12 December 2020

Oral absorption and bioavailability of tea catechins

1 reference

12 December 2020

Pharmacokinetics tricks and traps: flip-flop models

1 reference

12 December 2020

Pharmacokinetics of human growth hormone administered subcutaneously with two different injection systems

1 reference

12 December 2020

Application of in vitro-in vivo correlations (IVIVC) in setting formulation release specifications

1 reference

12 December 2020

Evidence for dissolution rate-limited absorption of COL-3, a matrix metalloproteinase inhibitor, leading to the irregular absorption profile in rats after oral administration

1 reference

12 December 2020

Pharmacokinetics and saturable renal tubular secretion of zidovudine in rats

1 reference

12 December 2020

Plasma pharmacokinetics and urinary excretion of thalidomide after oral dosing in healthy male volunteers

1 reference

12 December 2020

Power analyses of moment analysis parameter in bioequivalence tests

1 reference

12 December 2020

Pharmacokinetics of rimexolone after intra-articular administration

1 reference

12 December 2020

Absorption and disposition of epithiosteroids in rats (2): Avoidance of first-pass metabolism of mepitiostane by lymphatic absorption

1 reference

12 December 2020

In vivo evaluation of the semi-simultaneous method for bioavailability estimation using controlled intravenous infusion as an ‘extravascular’ route of administration

1 reference

12 December 2020

Pharmacokinetic study of 4'-acetamidophenyl-2-(5'-p-toluyl-1'-methylpyrrole)acetate in the rat

1 reference

12 December 2020

Pharmacokinetic and pharmacodynamic modeling of recombinant human erythropoietin after intravenous and subcutaneous dose administration in cynomolgus monkeys

1 reference

12 December 2020

Studies on Absorption and Excretion of Drug. VII. A New Estimation Method for the Release of Drugs from Dosage Forms and the Availability in vivo

1 reference

12 December 2020

Assessment of Pharmacokinetic Constants from Postinfusion Blood Curves Obtained after I.V. Infusion

1 reference

12 December 2020

Comparative plasma ampicillin levels and bioavailability of five parenteral ampicillin formulations in ruminant calves

1 reference

12 December 2020

The pharmacokinetic assessment of sodium cromoglycate

1 reference

12 December 2020

Bioavailability of amiodarone

1 reference

12 December 2020

Amiodarone disposition: polyexponential, power and gamma functions

1 reference

12 December 2020

Bumetanide and furosemide in heart failure

1 reference

12 December 2020

Furosemide absorption altered in decompensated congestive heart failure

1 reference

12 December 2020

Pharmacokinetics and bioavailability of cefazolin in horses

1 reference

12 December 2020

Assessment of drug absorption after oral administration

1 reference

12 December 2020

Nasal delivery of polypeptides I: nasal absorption of enkephalins in rats

1 reference

12 December 2020

Bovine plasma and synovial fluid kinetics of methylprednisolone and methylprednisolone acetate after intra-articular administration of methylprednisolone acetate

1 reference

12 December 2020

Effect of the injection site on the pharmacokinetics of procaine penicillin G in horses

1 reference

12 December 2020

Pharmacokinetics of sodium amoxicillin in horses

1 reference

12 December 2020

Smoking accelerates absorption of inhaled neutrophil elastase inhibitor FK706

1 reference

12 December 2020

Bioavailability of flumequine after semisimultaneous administration to veal calves

1 reference

12 December 2020

Pharmacokinetics and bioavailability of folic acid and plasma levels of bioactive folates after folic acid administration to pigs

1 reference

12 December 2020

The Bateman function revisited: a critical reevaluation of the quantitative expressions to characterize concentrations in the one compartment body model as a function of time with first-order invasion and first-order elimination

1 reference

12 December 2020

Disposition of creatine kinase activity in dog plasma following intravenous and intramuscular injection of skeletal muscle homogenates

1 reference

12 December 2020

A non‐invasive and quantitative method for the study of tissue injury caused by intramuscular injection of drugs in horses

1 reference

12 December 2020

Influence of route of administration and dosage form in the pharmacokinetics and bioavailability of salbutamol

1 reference

12 December 2020

Metabolic Fate of Ulinastatin (2); Pharmacokinetics in Rabbits Following Intra-Articular Administration

1 reference

12 December 2020

DeMonS--a new deconvolution method for estimating drug absorbed at different time intervals and/or drug disposition model parameters using a monotonic cubic spline

1 reference

12 December 2020

Identifiers

DOI

10.4155/TDE.11.19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21837267 AND SRC:MED&resulttype=core&format=json

10 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21837267 AND SRC:MED&resulttype=core&format=json

10 February 2020

PubMed publication ID

21837267

1 reference