Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy. (Q35146078)

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13 March 2020

case report

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title

Complete clinical regression of a BRAF V600E-mutant pediatric glioblastoma multiforme after BRAF inhibitor therapy (English)

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13 March 2020

1 reference

1

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13 March 2020

author name string

Brent A Orr

series ordinal

2

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13 March 2020

Amar Gajjar

series ordinal

3

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13 March 2020

language of work or name

English

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publication date

12 April 2014

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13 March 2020

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13 March 2020

volume

14

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13 March 2020

page(s)

258

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The integrated landscape of driver genomic alterations in glioblastoma

13 March 2020

cites work

1 reference

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Epithelioid GBMs show a high percentage of BRAF V600E mutation.

28 July 2018

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Which drug, and when, for patients with BRAF-mutant melanoma?

28 July 2018

1 reference

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Analysis of the BRAF(V600E) Mutation in Central Nervous System Tumors.

28 July 2018

1 reference

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Progression of RAS-mutant leukemia during RAF inhibitor treatment

28 July 2018

1 reference

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Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations

28 July 2018

1 reference

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Improved survival with MEK inhibition in BRAF-mutated melanoma

28 July 2018

1 reference

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Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

28 July 2018

1 reference

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Survival in BRAF V600-mutant advanced melanoma treated with vemurafenib

28 July 2018

1 reference

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RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors

28 July 2018

1 reference

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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

28 July 2018

1 reference

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Oncogenic BRAF mutation with CDKN2A inactivation is characteristic of a subset of pediatric malignant astrocytomas.

28 July 2018

1 reference

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Increased permeability of the blood-brain barrier to chemotherapy in metastatic brain tumors: establishing a treatment paradigm

28 July 2018

1 reference

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Vemurafenib in pediatric patients with BRAFV600E mutated high-grade gliomas.

28 July 2018

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BRAF inhibitor-driven tumor proliferation in a KRAS-mutated colon carcinoma is not overcome by MEK1/2 inhibition.

27 September 2018

1 reference

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Salvage therapy with BRAF inhibitors for recurrent pleomorphic xanthoastrocytoma: a retrospective case series

27 September 2018

1 reference

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Paradoxical activation and RAF inhibitor resistance of BRAF protein kinase fusions characterizing pediatric astrocytomas

27 September 2018

1 reference

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Brainstem ganglioglioma successfully treated with vemurafenib

27 September 2018

1 reference

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Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR.

27 September 2018

1 reference

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Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

27 September 2018

1 reference

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27 September 2018

Identifiers

DOI

10.1186/1471-2407-14-258

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725538 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725538 AND SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

24725538

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24725538 AND SRC:MED&resulttype=core&format=json