The basic aspects of therapeutics in amyotrophic lateral sclerosis (Q35143367)

6 August 2017

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title

The basic aspects of therapeutics in amyotrophic lateral sclerosis (English)

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amyotrophic lateral sclerosis

6 August 2017

main subject

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Michael J Strong

1

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publication date

1 June 2003

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Pharmacology & Therapeutics

6 August 2017

published in

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6 August 2017

volume

98

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6 August 2017

issue

3

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6 August 2017

page(s)

379-414

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Motor neuron disease in textile factory workers

6 August 2017

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Functional and pharmacokinetic studies of tetrahydroaminoacridine in patients with amyotrophic lateral sclerosis

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Associations between intermediate filament proteins expressed in cultured dorsal root ganglion neurons

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7 January 2021

Leukemia inhibitory factor by systemic administration rescues spinal motor neurons in the SOD1 G93A murine model of familial amyotrophic lateral sclerosis.

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7 January 2021

Potential role of an additive genetic component in the cause of amyotrophic lateral sclerosis and parkinsonism-dementia in the western Pacific

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7 January 2021

Perineuronal glial responses after axotomy of central and peripheral axons. A comparison

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7 January 2021

Increased 3‐nitrotyrosine in both sporadic and familial amyotrophic lateral sclerosis

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7 January 2021

Late onset of motor neurons in mice overexpressing wild-type peripherin

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7 January 2021

Formation of intermediate filament protein aggregates with disparate effects in two transgenic mouse models lacking the neurofilament light subunit

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7 January 2021

Pathological implications of nitric oxide, superoxide and peroxynitrite formation

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7 January 2021

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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7 January 2021

Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite

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7 January 2021

Stressed to death: regulation of apoptotic signaling pathways by the heat shock proteins

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7 January 2021

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A randomized controlled trial of recombinant interferon beta-1a in ALS. Italian Amyotrophic Lateral Sclerosis Study Group

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7 January 2021

Misdiagnosis in patients with amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The amyotrophic lateral sclerosis (ALS) patient perspective on misdiagnosis and its repercussions

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7 January 2021

Hereditary motor system diseases (chronic juvenile amyotrophic lateral sclerosis). Conditions combining a bilateral pyramidal syndrome with limb and bulbar amyotrophy

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7 January 2021

A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group

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7 January 2021

Detection and cellular localization of enterovirus RNA sequences in spinal cord of patients with ALS

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7 January 2021

Neurofilament light and polyadenylated mRNA levels are decreased in amyotrophic lateral sclerosis motor neurons

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7 January 2021

Localization of vimentin, the nonspecific intermediate filament protein, in embryonal glia and in early differentiating neurons. In vivo and in vitro immunofluorescence study of the rat embryo with vimentin and neurofilament antisera

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7 January 2021

Glycopyrrolate treatment of chronic drooling

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7 January 2021

A double-blind placebo-controlled trial ofl-threonine in amyotrophic lateral sclerosis

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7 January 2021

Increased oxidative damage to DNA in ALS patients

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7 January 2021

Differential microglial response to progressive neurodegeneration in the murine mutant Wobbler

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7 January 2021

A placebo-controlled trial of insulin-like growth factor-I in amyotrophic lateral sclerosis. European ALS/IGF-I Study Group

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7 January 2021

Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuronopathy.

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7 January 2021

Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death

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7 January 2021

Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis

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7 January 2021

Study of epidemiological and etiological factors of amyotrophic lateral sclerosis in the province of Florence, Italy

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7 January 2021

A double-blind controlled trial of bovine brain gangliosides in amyotrophic lateral sclerosis

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7 January 2021

Multiple sclerosis and amyotrophic lateral sclerosis in Mississippi

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7 January 2021

Controlled trial of thyrotropin releasing hormone in amyotrophic lateral sclerosis

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7 January 2021

El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. Subcommittee on Motor Neuron Diseases/Amyotrophic Lateral Sclerosis of the World Federation of Neurology Research Group on Neuromuscular Diseases a

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7 January 2021

Failure of immunosuppression with a ten- to 14-day course of high-dose intravenous cyclophosphamide to alter the progression of amyotrophic lateral sclerosis

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7 January 2021

The central nervous system in motor neurone disease

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7 January 2021

Hsp27 negatively regulates cell death by interacting with cytochrome c.

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7 January 2021

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

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7 January 2021

Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1

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7 January 2021

Motor neuron disease in England and Wales, 1959-1979

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7 January 2021

Fasting plasma and CSF amino acid levels in amyotrophic lateral sclerosis: a subtype analysis.

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7 January 2021

Mutation in neurofilament transgene implicates RNA processing in the pathogenesis of neurodegenerative disease

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7 January 2021

A double-blind, placebo-controlled trial of TRH in amyotrophic lateral sclerosis

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7 January 2021

Proximal axonal enlargement in motor neuron disease

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7 January 2021

Motor neurons are selectively vulnerable to AMPA/kainate receptor-mediated injury in vitro

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7 January 2021

Rapidly progressive aphasic dementia and motor neuron disease

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7 January 2021

Neuroblastoma x spinal cord (NSC) hybrid cell lines resemble developing motor neurons

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7 January 2021

Relationships between neuronal death and the cellular redox status. Focus on the developing nervous system.

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7 January 2021

Home mechanical ventilation for amyotrophic lateral sclerosis: nasal compared to tracheostomy-intermittent positive pressure ventilation

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7 January 2021

Linkage of the Gene for an Autosomal Dominant Form of Juvenile Amyotrophic Lateral Sclerosis to Chromosome 9q34

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7 January 2021

Patterns of Neurologic Diseases on Guam

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7 January 2021

Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice

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7 January 2021

Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments

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7 January 2021

Colocalization of NOS and SOD1 in neurofilament accumulation within motor neurons of amyotrophic lateral sclerosis: an immunohistochemical study

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7 January 2021

Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregation in ALS/MND.

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7 January 2021

Serpin=serine protease-like complexes within neurofilament conglomerates of motoneurons in amyotrophic lateral sclerosis

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7 January 2021

From Charcot to SOD1: mechanisms of selective motor neuron death in ALS.

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7 January 2021

Initial expression of neurofilaments and vimentin in the central and peripheral nervous system of the mouse embryo in vivo

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7 January 2021

An investigation into the early stages of the inflammatory response following ibotenic acid-induced neuronal degeneration

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7 January 2021

Abnormal SMN1 gene copy number is a susceptibility factor for amyotrophic lateral sclerosis

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7 January 2021

Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis

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7 January 2021

Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase

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7 January 2021

Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam

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7 January 2021

Superoxide Dismutase Catalyzes Nitration of Tyrosines by Peroxynitrite in the Rod and Head Domains of Neurofilament‐L

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7 January 2021

Epidemiology of mutations in superoxide dismutase in amyotrophic lateral sclerosis

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7 January 2021

Intrathecal administration of recombinant human superoxide dismutase 1 in amyotrophic lateral sclerosis: A preliminary safety and pharmacokinetic study

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7 January 2021

Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes

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7 January 2021

Lowered cerebral glucose utilization in amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuropsychological study of motor neuron disease

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Macrophages can modify the nonpermissive nature of the adult mammalian central nervous system

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A case-control study of amyotrophic lateral sclerosis.

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neurofibrillary axonal swellings and amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group

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7 January 2021

Contributions of anterior cingulate cortex to behaviour

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7 January 2021

Inhibition of cyclooxygenase-2 protects motor neurons in an organotypic model of amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Trial of immunosuppression in amyotrophic lateral sclerosis using total lymphoid irradiation

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Prostate apoptosis response-4 production in synaptic compartments following apoptotic and excitotoxic insults: evidence for a pivotal role in mitochondrial dysfunction and neuronal degeneration

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7 January 2021

2-Amino-3 (methylamino)-propionic acid in cycad-derived foods is an unlikely cause of amyotrophic lateral sclerosis/parkinsonism

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Quantification of the putative neurotoxin 2-amino-3-(methylamino)propanoic acid (BMAA) in cycadales: analysis of the seeds of some members of the family Cycadaceae

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increasing trend of ALS in France and elsewhere: are the changes real?

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Duration of amyotrophic lateral sclerosis is age dependent

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Upregulation of Bax protein and increased DNA degradation in ALS spinal cord motor neurons

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Apoptosis signals in sporadic amyotrophic lateral sclerosis: an immunocytochemical study.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The Guam cycad toxin methylazoxymethanol damages neuronal DNA and modulates tau mRNA expression and excitotoxicity

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Differential expression of two neuronal intermediate-filament proteins, peripherin and the low-molecular-mass neurofilament protein (NF-L), during the development of the rat

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-beta-galactosidase fusion protein

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis.

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Antecedent events in amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Evidence of Increased Oxidative Damage in Both Sporadic and Familial Amyotrophic Lateral Sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Differentiation driven by granulocyte-macrophage colony-stimulating factor endows microglia with interferon-gamma-independent antigen presentation function

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Expression of the gene for the neuronal intermediate filament protein alpha-internexin coincides with the onset of neuronal differentiation in the developing rat nervous system

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Decreased cytochrome c oxidase activity but unchanged superoxide dismutase and glutathione peroxidase activities in the spinal cords of patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Transglutaminase activity in serum and cerebrospinal fluid in sporadic amyotrophic lateral sclerosis: A possible use as an indicator of extent of the motor neuron loss

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A cutaneous disorder of connective tissue in amyotrophic lateral sclerosis. A histochemical study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and parkinsonian syndromes in high incidence among the Auyu and Jakai people of West New Guinea

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuropsychological, electroencephalogram and brain computed tomography findings in motor neuron disease

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Correlates of suffering in amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Positive effect of transplantation of hNT neurons (NTera 2/D1 cell-line) in a model of familial amyotrophic lateral sclerosis

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7 January 2021

Amyotrophic lateral sclerosis and parkinsonism-dementia of Gaum: Clinical, epidemiological, and genetic patterns.

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7 January 2021

Amyotrophic lateral sclerosis among Chamorro migrants from Guam

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https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and parkinsonism-dementia among Filipino migrants to Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Imaging of calcium and aluminum in neurofibrillary tangle-bearing neurons in parkinsonism-dementia of Guam

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7 January 2021

Intraneuronal deposition of calcium and aluminium in amyotropic lateral sclerosis of Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Disappearance of high-incidence amyotrophic lateral sclerosis and parkinsonism-dementia on Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Intraneuronal co-localization of silicon with calcium and aluminum in amyotrophic lateral sclerosis and parkinsonism with dementia of Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Bone mass in Guamanian patients with amyotrophic lateral sclerosis and parkinsonism-dementia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Low-calcium, high-aluminum diet-induced motor neuron pathology in cynomolgus monkeys

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Antecedent events in motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Spinal motor neuron neuroaxonal spheroids in chronic aluminum neurotoxicity contain phosphatase-resistant high molecular weight neurofilament (NFH).

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Epidemiologic study of amyotrophic lateral sclerosis in Sardinia, Italy

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Developmentally regulated stabilization of neuronal intermediate filaments in rat cerebral cortex

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Temporary amelioration of symptoms with intravenous cyclophosphamide in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Motor neuron disease in the province of Ferrara, Italy, in 1964-1982

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A clinical trial of dextromethorphan in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The mortality of motor neuron disease in Sweden

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Trials of ganglioside therapy for amyotrophic lateral sclerosis and diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A novel locus for familial amyotrophic lateral sclerosis, on chromosome 18q

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

X-linked recessive bulbospinal neuronopathy: a report of ten cases

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Use of radiotherapy for control of sialorrhea in patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Ganglioside therapy for amyotrophic lateral sclerosis: a double-blind controlled trial

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Motoneuron disease: a disorder secondary to solvent exposure?

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A morphological analysis of the motor neuron degeneration and microglial reaction in acute and chronic in vivo aluminum chloride neurotoxicity

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Motor neuronal death in sporadic amyotrophic lateral sclerosis (ALS) is not apoptotic. A comparative study of ALS and chronic aluminium chloride neurotoxicity in New Zealand white rabbits

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Activated microglia (BV-2) facilitation of TNF-alpha-mediated motor neuron death in vitro.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Plasma cysteine and sulphate levels in patients with motor neurone, Parkinson's and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Linkage of recessive familial amyotrophic lateral sclerosis to chromosome 2q33-q35.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis. A comparison of Guam and classical cases.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neurofilament gene expression: a major determinant of axonal caliber

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Linkage of familial amyotrophic lateral sclerosis with frontotemporal dementia to chromosome 9q21-q22

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The incidence of amyotrophic lateral sclerosis in southwestern Ontario, Canada

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuropathological features of frontotemporal dementia and parkinsonism linked to chromosome 17q21-22 (FTDP-17): Duke Family 1684.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Pharmacologic Treatment of Emotional Lability

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis: a double-blind crossover trial of thyrotropin-releasing hormone

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Familial amyotrophic lateral sclerosis with a mutation in exon 4 of the Cu/Zn superoxide dismutase gene: pathological and immunocytochemical changes

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Oxidative DNA damage induced by simultaneous generation of nitric oxide and superoxide

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Peroxynitrite formation from macrophage-derived nitric oxide

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cognitive impairment in amyotrophic lateral sclerosis and its relation to motor disabilities.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuropsychological dysfunctions in amyotrophic lateral sclerosis: relation to motor disabilities

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Survival prediction in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Analysis of chromosome 5q13 genes in amyotrophic lateral sclerosis: Homozygous naip deletion in a sporadic case

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Polymorphisms in the glutamate transporter gene EAAT2 in European ALS patients

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Evidence against increased oxidative stress in fibroblasts from patients with non-superoxide-dismutase-1 mutant familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Genetic analysis of the mammalian cell death machinery

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Mice overexpressing the human neurofilament heavy gene as a model of ALS.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Changes in the incidence of amyotrophic lateral sclerosis in Israel

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Alpha-internexin, a novel neuronal intermediate filament protein, precedes the low molecular weight neurofilament protein (NF-L) in the developing rat brain

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Nutritional status of patients with amyotrophic lateral sclerosis: relation to the proximity of death

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Involvement of the frontotemporal lobe and limbic system in amyotrophic lateral sclerosis: as assessed by serial computed tomography and magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Advanced glycation endproduct-modified superoxide dismutase-1 (SOD1)-positive inclusions are common to familial amyotrophic lateral sclerosis patients with SOD1 gene mutations and transgenic mice expressing human SOD1 with a G85R mutation

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Galectin-1 Is a Component of Neurofilamentous Lesions in Sporadic and Familial Amyotrophic Lateral Sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Co-induction of argininosuccinate synthetase, cationic amino acid transporter-2, and nitric oxide synthase in activated murine microglial cells.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Morphometric Comparison of the Vulnerability of Peripheral Motor and Sensory Neurons in Amyotrophic Lateral Sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Plasmapheresis with immunosuppression in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Progressive proximal spinal and bulbar muscular atrophy of late onset. A sex-linked recessive trait

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Content of the neurotoxins cycasin (methylazoxymethanol -D-glucoside) and BNLAA ( -N-methylamino-L-alanine) in cycad flour prepared by Guam Chamorros

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Calcineurin A and calbindin immunoreactivity in the spinal cord of G93A superoxide dismutase transgenic mice

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Skin involvement in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Case-control studies of motor neuron disease: association with mechanical injuries

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Overexpression of neurofilament subunit NF-L and NF-H extends survival of a mouse model for amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Developmental patterns of intermediate filament gene expression in the normal hamster brain

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and Parkinson's disease complex on Guam linked to an environmental neurotoxin

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Epidemiologic investigations of amyotrophic lateral sclerosis. I. Preliminary report on geographic distribution, with special reference to the Mariana Islands, including clinical and pathologic observations

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A double-blind, placebo-controlled trial of high doses of gangliosides in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis/Riluzole Study Group II

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Effect of recombinant human insulin-like growth factor-I on progression of ALS. A placebo-controlled study. The North America ALS/IGF-I Study Group

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Clinical correlations of anti-GM1 antibodies in amyotrophic lateral sclerosis and neuropathies

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Major histocompatibility complex antigen expression in the affected tissues in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Selegiline Is Ineffective in a Collaborative Double-blind, Placebo-Controlled Trial for Treatment of Amyotrophic Lateral Sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neurofilaments are obligate heteropolymers in vivo

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cytoskeletal abnormalities in motor neuron disease. An immunocytochemical study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

New aspects of the pathology of neurodegenerative disorders as revealed by ubiquitin antibodies

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Regulation of prostanoid synthesis in microglial cells and effects of prostaglandin E2 on microglial functions

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Morbidity and mortality in motor neuron disease: comparison with multiple sclerosis and Parkinson's disease: age and sex specific rates and cohort analyses

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Rising mortality from motoneuron disease in the USA, 1962-84.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Peroxynitrite-induced apoptosis in HL-60 cells

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Aberrant RNA Processing in a Neurodegenerative Disease: the Cause for Absent EAAT2, a Glutamate Transporter, in Amyotrophic Lateral Sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Suppression of nitric oxide formation by tyrosine kinase inhibitors in murine N9 microglia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

N-isopropyl-p-123I-amphetamine single photon emission computer tomography in motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Frontal lobe function in amyotrophic lateral sclerosis: a neuropsychologic and positron emission tomography study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Clinical characteristics of a family with chromosome 17-linked disinhibition-dementia-parkinsonism-amyotrophy complex

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

An ALS-like syndrome with new HIV infection and complete response to antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Pathoanatomic changes in amyotrophic lateral sclerosis on Guam. Special reference to the occurrence of neurofibrillary changes

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of a programmed cell death mechanism

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

p53 is abnormally elevated and active in the CNS of patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Prevalence and correlates of neuropsychological deficits in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Functional and morphometric study of the liver in motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

An open-randomized clinical trial of selegiline in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Percutaneous endoscopic gastrostomy and enteral nutrition in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Familial nature and continuing morbidity of the amyotrophic lateral sclerosis-parkinsonism dementia complex of Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis. A study of central monoamine metabolism and therapeutic trial of levodopa

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Intravenous immunoglobulin therapy in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Sporadic ALS and chromosome 22: evidence for a possible neurofilament gene defect

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Studies of the coding region of the neuronal glutamate transporter gene in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The EAAT2 (GLT-1) gene in motor neuron disease: absence of mutations in amyotrophic lateral sclerosis and a point mutation in patients with hereditary spastic paraplegia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

c-Jun, JNK/SAPK Kinase and Transcription Factor NF-κB Are Selectively Activated in Astrocytes, but not Motor Neurons, in Amyotrophic Lateral Sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Placebo-controlled trial of gabapentin in patients with amyotrophic lateral sclerosis. WALS Study Group. Western Amyotrophic Lateral Sclerosis Study Group

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A placebo-controlled trial of recombinant human ciliary neurotrophic (rhCNTF) factor in amyotrophic lateral sclerosis. rhCNTF ALS Study Group

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Controlled trial of nimodipine in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A clinical trial of verapamil in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Practice parameter: the care of the patient with amyotrophic lateral sclerosis (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology: ALS Practice Parameters Task Force

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis: effects of acute intravenous and chronic subcutaneous administration of thyrotropin-releasing hormone in controlled trials

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Presenile dementia with motor neuron disease in Japan: clinico-pathological review of 26 cases

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Expression of NF-L and NF-M in fibroblasts reveals coassembly of neurofilament and vimentin subunits

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Intrathecal administration of natural human interferon alpha in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The genetic and pathological classification of familial frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Altered expression of bcl-2 and bax mRNA in amyotrophic lateral sclerosis spinal cord motor neurons

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amantadine and guanidine are ineffective in ALS

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Immunocytochemical and ultrastructural studies of lower motor neurons in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Immunocytochemical and ultrastructural studies of upper motor neurons in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Individuals with amyotrophic lateral sclerosis are in caloric balance despite losses in mass

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Frontal lobe dementia and motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. II. Diet

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Population-based case-control study of amyotrophic lateral sclerosis in western Washington State. I. Cigarette smoking and alcohol consumption

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The effect of non-invasive positive pressure ventilation (NIPPV) on cognitive function in amyotrophic lateral sclerosis (ALS): a prospective study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Dynamics of neuronal intermediate filaments: a developmental perspective

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Motor neurone disease: towards better care

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Spinal fluid cells and protein in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Trial of oral physostigmine in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

New ubiquitin-positive intraneuronal inclusions in the extra-motor cortices in patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Ubiquitin-positive intraneuronal inclusions in the extramotor cortices of presenile dementia patients with motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Plasmapheresis in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The quality of care and symptom control--the effects on the terminal phase of ALS/MND.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Therapeutic trial of tilorone in ALS: Lack of benefit in a double-blind, placebo-controlled study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Alterations of skin glycosaminoglycans in patients with ALS.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyloid beta protein in skin of patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Decreased urinary concentrations of type IV collagen in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increased type III procollagen in serum and skin of patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increased expression of insulin-like growth factor I in skin in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increased expression of laminin 1 in the skin of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increased cystatin C immunoreactivity in the skin in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Familial amyotrophic lateral sclerosis with a point mutation of SOD-1: intrafamilial heterogeneity of disease duration associated with neurofibrillary tangles

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The reaction of nitric oxide with organic peroxyl radicals

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Spinobulbar muscular atrophy can mimic ALS: The importance of genetic testing in male patients with atypical ALS

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Distribution of a novel 57 kDa intermediate filament (IF) protein in the nervous system.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Some neural intermediate filaments contain both peripherin and the neurofilament proteins

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Protein modification by the lipid peroxidation product 4-hydroxynonenal in the spinal cords of amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The lipid peroxidation product 4-hydroxynonenal impairs glutamate and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The prostate apoptosis response-4 protein participates in motor neuron degeneration in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Intraneuronal aluminum accumulation in amyotrophic lateral sclerosis and Parkinsonism-dementia of Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Serum antibodies to GM1 ganglioside in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Murine brain macrophages induced NMDA receptor mediated neurotoxicity in vitro by secreting glutamate

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Histochemical and X-ray microanalytical localization of aluminum in amyotrophic lateral sclerosis and parkinsonism-dementia of Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Respiratory assistance with a non-invasive ventilator (Bipap) in MND/ALS patients: survival rates in a controlled trial.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cortical bone loss and measurements of the second metacarpal bone. I. Comparisons between adult Guamanian Chamorros and American Caucasians

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and parkinsonism-dementia on Guam: a 25-year prospective case-control study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuropsychological measures in amyotrophic lateral sclerosis and their relationship with CT scan-assessed cerebral atrophy.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

TAU as a susceptibility gene for amyotropic lateral sclerosis-parkinsonism dementia complex of Guam

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Activated Macrophage/Microglial Cells Can Promote the Regeneration of Sensory Axons into the Injured Spinal Cord

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Autosomal dominant juvenile amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Resilience and distress among amyotrophic lateral sclerosis patients and caregivers

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increase of macrophage colony-stimulating factor and granulocyte-macrophage colony-stimulating factor receptors in the regenerating rat facial nucleus

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Inhibition of posttraumatic microglial proliferation in a genetic model of macrophage colony-stimulating factor deficiency in the mouse

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and parkinsonism-dementia on Guam, 1945-1972. I. Descriptive epidemiology

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A cohort study of amyotrophic lateral sclerosis and parkinsonism-dementia on Guam and Rota

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Longitudinal Gompertzian analysis of amyotrophic lateral sclerosis mortality in the U.S., 1977-1986: evidence for an inherently susceptible population subset

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Modified snake venom in amyotrophic lateral sclerosis. Lack of clinical effectiveness

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

An Analysis of Extended Survival in Patients With Amyotrophic Lateral Sclerosis Treated With Riluzole

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Apoptotic death of neurons exhibiting peripherin aggregates is mediated by the proinflammatory cytokine tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and parkinsonism-dementia on Guam: a 30-year evaluation of clinical and neuropathologic trends

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Analysis of the KSP repeat of the neurofilament heavy subunit in familiar amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Studies on epidemiological, clinical, and etiological aspects of ALS disease in Sardinia, Southern Italy

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Patients with Amyotrophic Lateral Sclerosis and Other Neurodegenerative Diseases Have Increased Levels of Neurofilament Protein in CSF

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Toward earlier diagnosis of amyotrophic lateral sclerosis: revised criteria. rhCNTF ALS Study Group

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Peroxynitrite causes apoptosis in rat thymocytes

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Peroxynitrite causes DNA nicks in plasmid pBR322

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Motor neuron diseases and amyotrophic lateral sclerosis: GM1 antibodies and paraproteinemia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Apoptosis in amyotrophic lateral sclerosis: a review of the evidence.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Treatment of pathologic laughing and weeping with amitriptyline

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Simultaneous up-regulation of neurofilament proteins during the postnatal development of the rat nervous system

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neurodegenerative diseases: occupational occurrence and potential risk factors, 1982 through 1991

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neurofibrillary tangles of Guam parkinson-dementia are associated with reactive microglia and complement proteins

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Deletion of 3′-Untranslated Region Alters the Level of mRNA Expression of a Neurofilament Light Subunit Transgene

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cerebrospinal fluid interleukin 6 in amyotrophic lateral sclerosis: immunological parameter and comparison with inflammatory and non-inflammatory central nervous system diseases

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Differential expression of neurofilament triplet proteins in brain development

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

CSF and plasma amino acid levels in motor neuron disease: elevation of CSF glutamate in a subset of patients

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Oxidative damage to protein in sporadic motor neuron disease spinal cord

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuronal intermediate filament protein alpha-internexin facilitates axonal neurite elongation in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Presence of Cu/Zn superoxide dismutase (SOD) immunoreactivity in neuronal hyaline inclusions in spinal cords from mice carrying a transgene for Gly93Ala mutant human Cu/Zn SOD

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Upregulation of the pro-apoptotic BH3-only peptide harakiri in spinal neurons of amyotrophic lateral sclerosis patients

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Linkage of a gene causing familial amyotrophic lateral sclerosis to chromosome 21 and evidence of genetic-locus heterogeneity

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Debrisoquine hydroxylase gene polymorphism frequencies in patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis. A case-control study following detection of a cluster in a small Wisconsin community

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Autoradiography with [3H]PK11195 of spinal tract degeneration in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Recombinant growth hormone treatment of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Expression of the neurofilament protein NF-H in L cells

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cycad use and motor neurone disease in Kii peninsula of Japan

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

An alternative, nonapoptotic form of programmed cell death

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Glutamate levels in cerebrospinal fluid in amyotrophic lateral sclerosis: a reappraisal using a new HPLC method with coulometric detection in a large cohort of patients

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Molecular parameters of type IV alpha-internexin and type IV-type III alpha-internexin-vimentin copolymer intermediate filaments

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Preliminary study of glycopyrrolate in the management of drooling

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A characteristic ganglioside antibody pattern in the CSF of patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Microglial-neuronal interactions

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic lateral sclerosis and occupational history. A pilot case-control study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Progress in clinical neurosciences: the evidence for ALS as a multisystems disorder of limited phenotypic expression.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Reversibility of neurofilamentous inclusion formation following repeated sublethal intracisternal inoculums of AlCl3 in New Zealand white rabbits

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cognition, language, and speech in amyotrophic lateral sclerosis: a review.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Nitration of the Low Molecular Weight Neurofilament Is Equivalent in Sporadic Amyotrophic Lateral Sclerosis and Control Cervical Spinal Cord

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A prospective study of cognitive impairment in ALS

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Percutaneous gastrojejunostomy in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Phosphorylation state of the native high-molecular-weight neurofilament subunit protein from cervical spinal cord in sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Mitochondria in sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

DNA strand breakage and activation of poly-ADP ribosyltransferase: a cytotoxic pathway triggered by peroxynitrite

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

DNA strand breakage, activation of poly (ADP-ribose) synthetase, and cellular energy depletion are involved in the cytotoxicity of macrophages and smooth muscle cells exposed to peroxynitrite

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Role of poly-ADP ribosyltransferase activation in the vascular contractile and energetic failure elicited by exogenous and endogenous nitric oxide and peroxynitrite

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Peroxynitrite causes energy depletion and increases permeability via activation of poly (ADP-ribose) synthetase in pulmonary epithelial cells

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Familial amyotrophic lateral sclerosis with a mutation in the Cu/Zn superoxide dismutase gene

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Inter-relation between "classic" motor neuron disease and frontotemporal dementia: neuropsychological and single photon emission computed tomography study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Immunosuppressive treatment of motor neuron syndromes. Attempts to distinguish a treatable disorder

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cerebral blood flow and oxygen metabolism in progressive dementia associated with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The Relationship of Microglial Cells to Dying Neurons During Natural Neuronal Cell Death and Axotomy-induced Degeneration of the Rat Retina

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Treatment of the adult retina with microglia-suppressing factors retards axotomy-induced neuronal degradation and enhances axonal regeneration in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A controlled trial of recombinant methionyl human BDNF in ALS: The BDNF Study Group (Phase III)

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Branched-chain amino acids and amyotrophic lateral sclerosis: a treatment failure? The Italian ALS Study Group

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Minocycline provides neuroprotection against N-methyl-D-aspartate neurotoxicity by inhibiting microglia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Minocycline prevents neurotoxicity induced by cerebrospinal fluid from patients with motor neurone disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increase in oxidized NO products and reduction in oxidized glutathione in cerebrospinal fluid from patients with sporadic form of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Remarkable increase in cerebrospinal fluid 3-nitrotyrosine in patients with sporadic amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS)

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Brain destruction alone does not elevate brain aluminum

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Amyotrophic Lateral Sclerosis Mimic Syndromes

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Expression of neurofilament subunits in neurons of the central and peripheral nervous system: an immunohistochemical study with monoclonal antibodies

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Immunohistochemical characterization of the inflammatory infiltrate in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Neuronophagia in the motor cortex in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Apoptosis in amyotrophic lateral sclerosis is not restricted to motor neurons. Bcl-2 expression is increased in unaffected post-central gyrus

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Glutamine synthetase in cerebrospinal fluid, serum, and brain: a diagnostic marker for Alzheimer disease?

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Pathologic laughing and crying treated with levodopa

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite. Evidence for hydroxyl radical production from peroxynitrite

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Glutamatergic receptors regulate expression, phosphorylation and accumulation of neurofilaments in spinal cord neurons

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Bunina bodies in amyotrophic lateral sclerosis on Guam: a histochemical, immunohistochemical and ultrastructural investigation

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Focal reductions of cerebral blood flow in amyotrophic lateral sclerosis: a [99mTc]-d,l-HMPAO SPECT study

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Prevention of peroxynitrite-dependent tyrosine nitration and inactivation of alpha1-antiproteinase by antibiotics

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

1 reference

7 January 2021

Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Hippocampal and neocortical ubiquitin-immunoreactive inclusions in amyotrophic lateral sclerosis with dementia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Cognitive impairment in sporadic ALS: a pathologic continuum underlying a multisystem disorder

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Nitric oxide synthase expression in cervical spinal cord in sporadic amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increasing neurofilament subunit NF-M expression reduces axonal NF-H, inhibits radial growth, and results in neurofilamentous accumulation in motor neurons.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Characterization of neuronal intermediate filament protein expression in cervical spinal motor neurons in sporadic amyotrophic lateral sclerosis (ALS).

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The epidemiology of motor neuron diseases: a review of recent studies

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Epidemiological surveillance of amyotrophic lateral sclerosis and parkinsonism-dementia in the Commonwealth of the Northern Mariana Islands

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Calcium and vitamin D metabolism in Guamanian Chamorros with amyotrophic lateral sclerosis and parkinsonism-dementia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

The pathogenesis of amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Follow-up study on amyotrophic lateral sclerosis in Rochester, Minn., 1925 through 1984.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Patterns of acquiring parkinsonism-dementia complex on Guam. 1944 through 1985.

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Bactericidal activity of peroxynitrite

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

https://api.crossref.org/works/10.1016/S0163-7258(03)50040-8

7 January 2021

10.1016/S0163-7258(03)00040-8

Identifiers

DOI

1 reference

6 August 2017

1 reference