Calpain-Mediated Tau Cleavage: A Mechanism Leading to Neurodegeneration Shared by Multiple Tauopathies (Q35136746)

6 August 2017

title

Calpain-mediated tau cleavage: a mechanism leading to neurodegeneration shared by multiple tauopathies (English)

1 reference

6 August 2017

Calpain-Mediated Tau Cleavage: A Mechanism Leading to Neurodegeneration Shared by Multiple Tauopathies (English)

1 reference

DOI

https://api.crossref.org/works/10.2119/MOLMED.2010.00220

28 November 2024

1 reference

1 reference

2

Eileen H Bigio

1 reference

6 August 2017

1

Adriana Ferreira

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21442128

28 November 2024

language of work or name

English

0 references

publication date

21 March 2011

1 reference

full work available at URL

6 August 2017

https://molmed.biomedcentral.com/counter/pdf/10.2119/molmed.2010.00220

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21442128

https://europepmc.org/articles/PMC3146621

28 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21442128

https://europepmc.org/articles/PMC3146621?pdf=render

28 November 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21442128

https://doi.org/10.2119/molmed.2010.00220

28 November 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC:MED AND EXT_ID:21442128

http://www.crossref.org/molmed.2010.00220

28 November 2024

1 reference

DOI

https://api.crossref.org/works/10.2119/MOLMED.2010.00220

http://link.springer.com/content/pdf/10.2119/molmed.2010.00220.pdf

28 November 2024

1 reference

https://api.crossref.org/works/10.2119/MOLMED.2010.00220

28 November 2024

1 reference

6 August 2017

volume

17

1 reference

6 August 2017

issue

7-8

1 reference

6 August 2017

page(s)

676-685

1 reference

Membrane cholesterol modulates {beta}-amyloid-dependent tau cleavage by inducing changes in the membrane content and localization of N-methyl-D-aspartic acid receptors

6 August 2017

cites work

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Tau is essential to beta -amyloid-induced neurotoxicity

28 July 2018

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28 July 2018

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28 July 2018

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Neuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicity

28 July 2018

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Neurotoxicity induces cleavage of p35 to p25 by calpain

28 July 2018

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Selective Phosphorylation of Adult Tau Isoforms in Mature Hippocampal Neurons Exposed to Fibrillar Aβ

28 July 2018

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MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption

28 July 2018

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Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration

28 July 2018

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Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity

28 July 2018

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Developmental changes in tau phosphorylation: fetal tau is transiently phosphorylated in a manner similar to paired helical filament-tau characteristic of Alzheimer's disease.

28 July 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

28 July 2018

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28 July 2018

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Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

28 July 2018

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Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

28 July 2018

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28 July 2018

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The switch of tau protein to an Alzheimer-like state includes the phosphorylation of two serine-proline motifs upstream of the microtubule binding region

28 July 2018

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Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state

28 July 2018

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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase

28 July 2018

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28 July 2018

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p42 MAP kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1. Implications for Alzheimer's disease [corrected]

28 July 2018

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Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications

28 July 2018

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Growth of a rat neuroblastoma cell line in serum-free supplemented medium

28 July 2018

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Cleavage of Tau by calpain in Alzheimer's disease: the quest for the toxic 17 kD fragment

28 July 2018

1 reference

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Brain-derived neurotrophic factor and epidermal growth factor activate neuronal m-calpain via mitogen-activated protein kinase-dependent phosphorylation

27 September 2018

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The novel calpain inhibitor A-705253 potently inhibits oligomeric beta-amyloid-induced dynamin 1 and tau cleavage in hippocampal neurons.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3146621

Calpastatin levels affect calpain activation and calpain proteolytic activity in APP transgenic mouse model of Alzheimer's disease

27 September 2018

1 reference

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Characteristics of the binding of thioflavin S to tau paired helical filaments.

27 September 2018

1 reference

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beta-Amyloid-induced dynamin 1 degradation is mediated by N-methyl-D-aspartate receptors in hippocampal neurons.

27 September 2018

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Spectrin and calpain: a 'target' and a 'sniper' in the pathology of neuronal cells.

27 September 2018

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Triggers of full-length tau aggregation: a role for partially folded intermediates.

27 September 2018

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Site-specific nitration and oxidative dityrosine bridging of the tau protein by peroxynitrite: implications for Alzheimer's disease

27 September 2018

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Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ

27 September 2018

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Alteration in calcium channel properties is responsible for the neurotoxic action of a familial frontotemporal dementia tau mutation

27 September 2018

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Calpain activation in neurodegenerative diseases: confocal immunofluorescence study with antibodies specifically recognizing the active form of calpain 2.

27 September 2018

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Ligand-dependent tau filament formation: implications for Alzheimer's disease progression.

27 September 2018

1 reference

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Tau Released from Paired Helical Filaments with Formic Acid or Guanidine Is Susceptible to Calpain‐Mediated Proteolysis

27 September 2018

1 reference

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Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: distinction between PHF-like immunoreactivity and microtubule binding.

27 September 2018

1 reference

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Abnormal tau phosphorylation at Ser396 in Alzheimer's disease recapitulates development and contributes to reduced microtubule binding

27 September 2018

1 reference

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beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

27 September 2018

1 reference

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Tau and transgenic animal models

27 September 2018

1 reference

https://api.crossref.org/works/10.2119/MOLMED.2010.00220

N-terminal fragments of tau inhibit full-length tau polymerization in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.2119/MOLMED.2010.00220

Peroxynitrite-mediated tau modifications stabilize preformed filaments and destabilize microtubules through distinct mechanisms

31 March 2020

1 reference

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PD98059 prevents neurite degeneration induced by fibrillar beta-amyloid in mature hippocampal neurons

31 March 2020

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A luminol/iodophenol chemiluminescent detection system for western immunoblots

31 March 2020

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https://api.crossref.org/works/10.2119/MOLMED.2010.00220

Assay of proteins in the presence of interfering materials

31 March 2020

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https://api.crossref.org/works/10.2119/MOLMED.2010.00220

[18] Quantification of β-sheet amyloid fibril structures with thioflavin T

31 March 2020

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https://api.crossref.org/works/10.2119/MOLMED.2010.00220

Calpain‐Induced Proteolysis of Normal Human Tau and Tau Associated with Paired Helical Filaments

31 March 2020

1 reference

https://api.crossref.org/works/10.2119/MOLMED.2010.00220

p42 map kinase phosphorylation sites in microtubule-associated protein tau are dephosphorylated by protein phosphatase 2A1Implications for Alzheimer's disease

31 March 2020

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https://api.crossref.org/works/10.2119/MOLMED.2010.00220

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

31 March 2020

1 reference

https://api.crossref.org/works/10.2119/MOLMED.2010.00220

31 March 2020

Identifiers

DOI

1 reference

Dimensions Publication ID

6 August 2017

0 references

1 reference

6 August 2017

1 reference