Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice. (Q35120292)

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13 February 2020

title

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice (English)

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1

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Pedro Fernández-Salguero

8

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13 February 2020

Pinpin Lin

10

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13 February 2020

Stavros Garantziotis

12

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author name string

Uma T Shankavaram

2

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13 February 2020

Mahadev Rao

3

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Nicole Datrice

4

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13 February 2020

Scott Atay

5

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Marta Aparicio

6

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13 February 2020

Kevin A Camphausen

7

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13 February 2020

Han Chang

9

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David S Schrump

11

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13 February 2020

Frank Cuttitta

13

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Enrique Zudaire

14

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language of work or name

English

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publication date

19 September 2012

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13 February 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993405 AND SRC:MED&resulttype=core&format=json

13 February 2020

volume

72

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issue

22

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13 February 2020

page(s)

5790-5800

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Adrenomedullin expression in epithelial ovarian cancers and promotes HO8910 cell migration associated with upregulating integrin α5β1 and phosphorylating FAK and paxillin

13 February 2020

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Adrenomedullin interacts with VEGF in endometrial cancer and has varied modulation in tumours of different grades.

9 July 2018

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Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation

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Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs.

9 July 2018

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Adrenomedullin promotes cell cycle transit and up-regulates cyclin D1 protein level in human glioblastoma cells through the activation of c-Jun/JNK/AP-1 signal transduction pathway

9 July 2018

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The aryl hydrocarbon receptor repressor is a putative tumor suppressor gene in multiple human cancers

9 July 2018

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Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression.

9 July 2018

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Requirement of aryl hydrocarbon receptor overexpression for CYP1B1 up-regulation and cell growth in human lung adenocarcinomas

9 July 2018

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Cigarette smoke as a trigger for the dioxin receptor-mediated signaling pathway

9 July 2018

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Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis

9 July 2018

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Ether stress increases adrenomedullin gene expression and levels in the rat adrenal

9 July 2018

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Adrenomedullin and tumour angiogenesis.

9 July 2018

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Identification of vasoactive nonpeptidic positive and negative modulators of adrenomedullin using a neutralizing antibody-based screening strategy

9 July 2018

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Tobacco and cancer: recent epidemiological evidence

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Adrenomedullin and cancer

9 July 2018

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The effects of adrenomedullin overexpression in breast tumor cells

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A constitutively active dioxin/aryl hydrocarbon receptor induces stomach tumors

9 July 2018

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Neutralization of adrenomedullin inhibits the growth of human glioblastoma cell lines in vitro and suppresses tumor xenograft growth in vivo

9 July 2018

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Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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27 September 2018

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The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts

27 September 2018

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A constitutively active dioxin/aryl hydrocarbon receptor promotes hepatocarcinogenesis in mice

27 September 2018

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Second hand smoke stimulates tumor angiogenesis and growth

27 September 2018

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Overexpression of aryl hydrocarbon receptor in human lung carcinomas.

27 September 2018

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Adrenomedullin inhibits hypoxic cell death by upregulation of Bcl-2 in endometrial cancer cells: a possible promotion mechanism for tumour growth

27 September 2018

1 reference

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Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis.

27 September 2018

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Effects of acute restraint stress on endogenous adrenomedullin levels.

27 September 2018

1 reference

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Enhancing power while controlling family-wise error: an illustration of the issues using electrocortical studies

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22993405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Expression of adrenomedullin in normal human lung and in pulmonary tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22993405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tobacco smoke induces urokinase-type plasminogen activator and cell invasiveness: evidence for an epidermal growth factor receptor dependent mechanism

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22993405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-12-0818

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993405 AND SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22993405 AND SRC:MED&resulttype=core&format=json

13 February 2020

PubMed publication ID

22993405

1 reference