Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension (Q35115837)

6 August 2017

title

Deficiency of Akt1, but not Akt2, attenuates the development of pulmonary hypertension (English)

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6 August 2017

Richard D Ye

8

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Stefan Offermanns

object named as

Stefan Offermanns

7

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author name string

Haiyang Tang

1

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6 August 2017

Jiwang Chen

2

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6 August 2017

Dustin R Fraidenburg

3

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6 August 2017

Shanshan Song

4

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6 August 2017

Justin R Sysol

5

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6 August 2017

Abigail R Drennan

6

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6 August 2017

Marcelo G Bonini

9

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6 August 2017

Richard D Minshall

10

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6 August 2017

Joe G N Garcia

11

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6 August 2017

Roberto F Machado

12

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6 August 2017

Ayako Makino

13

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6 August 2017

Jason X-J Yuan

14

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6 August 2017

language of work or name

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21 November 2014

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American Journal of Physiology - Lung Cellular and Molecular Physiology

6 August 2017

published in

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6 August 2017

volume

308

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6 August 2017

issue

2

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6 August 2017

page(s)

L208-20

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describes a project that uses

6 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4338938/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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9 July 2018

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9 July 2018

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9 July 2018

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Role for Akt3/protein kinase Bgamma in attainment of normal brain size

9 July 2018

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9 July 2018

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9 July 2018

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Sirolimus-Eluting Stents versus Standard Stents in Patients with Stenosis in a Native Coronary Artery

9 July 2018

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PDGF stimulates pulmonary vascular smooth muscle cell proliferation by upregulating TRPC6 expression

9 July 2018

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Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells

9 July 2018

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Ion channels in pulmonary arterial hypertension

9 July 2018

1 reference

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The phosphatidylinositol 3-Kinase AKT pathway in human cancer

9 July 2018

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Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

9 July 2018

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Upregulated TRP and enhanced capacitative Ca(2 ) entry in human pulmonary artery myocytes during proliferation

9 July 2018

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Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines.

9 July 2018

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Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA

9 July 2018

1 reference

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Hypoxic and metabolic regulation of voltage-gated K channels in rat pulmonary artery smooth muscle cells

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Inhibition of Orai1-mediated Ca(2 ) entry is a key mechanism of the antiproliferative action of sirolimus in human arterial smooth muscle.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Macitentan and morbidity and mortality in pulmonary arterial hypertension

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Cortistatin inhibits migration and proliferation of human vascular smooth muscle cells and decreases neointimal formation on carotid artery ligation.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Sodium butyrate inhibits platelet-derived growth factor-induced proliferation and migration in pulmonary artery smooth muscle cells through Akt inhibition

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Activation of PPAR-α induces cell cycle arrest and inhibits transforming growth factor-β1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

mTOR regulates vascular smooth muscle cell differentiation from human bone marrow-derived mesenchymal progenitors

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Targeted deletion of PTEN in smooth muscle cells results in vascular remodeling and recruitment of progenitor cells through induction of stromal cell-derived factor-1alpha.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling

27 September 2018

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Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors.

27 September 2018

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The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

27 September 2018

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Rapamycin inhibits proliferation and differentiation of human endothelial progenitor cells in vitro

27 September 2018

1 reference

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Diversity of voltage-dependent K channels in human pulmonary artery smooth muscle cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4338938

Fibroblast growth factor mediates hypoxia-induced endothelin-- a receptor expression in lung artery smooth muscle cells

27 September 2018

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Inhibition of endogenous TRP1 decreases capacitative Ca2 entry and attenuates pulmonary artery smooth muscle cell proliferation

27 September 2018

1 reference

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AKT proto-oncogene overexpression is an early event during sporadic colon carcinogenesis

27 September 2018

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Sustained membrane depolarization and pulmonary artery smooth muscle cell proliferation.

27 September 2018

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Pulmonary artery NADPH-oxidase is activated in hypoxic pulmonary vasoconstriction.

27 September 2018

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BMPR-II deficiency elicits pro-proliferative and anti-apoptotic responses through the activation of TGFβ-TAK1-MAPK pathways in PAH

27 September 2018

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Upregulation of Na /Ca2 exchanger contributes to the enhanced Ca2 entry in pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension

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World Health Organization Class III COPD-associated pulmonary hypertension: are we there yet in understanding the pathobiology of the disease?

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Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling

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Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference