A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity. (Q35109579)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25425577 AND SRC:MED&resulttype=core&format=json

23 February 2020

title

A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity (English)

1 reference

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23 February 2020

0 references

0 references

7

1 reference

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23 February 2020

author name string

Dong-Hyun Kim

1

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23 February 2020

Zhen Xiao

2

1 reference

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23 February 2020

Sanghoon Kwon

3

1 reference

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23 February 2020

Xiaoxiao Sun

4

1 reference

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23 February 2020

Daniel Ryerson

5

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23 February 2020

David Tkac

6

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23 February 2020

Shwu-Yuan Wu

8

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23 February 2020

Cheng-Ming Chiang

9

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23 February 2020

Edward Zhou

10

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23 February 2020

H Eric Xu

11

1 reference

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23 February 2020

Jorma J Palvimo

12

1 reference

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23 February 2020

Lin-Feng Chen

13

1 reference

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23 February 2020

Byron Kemper

14

1 reference

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23 February 2020

Jongsook Kim Kemper

15

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23 February 2020

language of work or name

English

0 references

publication date

25 November 2014

1 reference

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23 February 2020

number of pages

16

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based on heuristic

inferred from page(s)

published in

The EMBO Journal

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23 February 2020

volume

34

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23 February 2020

issue

2

1 reference

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23 February 2020

page(s)

184-199

1 reference

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Structure of the retinoid X receptor α-liver X receptor β (RXRα-LXRβ) heterodimer on DNA

23 February 2020

cites work

1 reference

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SUMOylation of the farnesoid X receptor (FXR) regulates the expression of FXR target genes

9 July 2018

1 reference

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9 July 2018

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Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.

9 July 2018

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Genomic analysis of hepatic farnesoid X receptor binding sites reveals altered binding in obesity and direct gene repression by farnesoid X receptor in mice

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9 July 2018

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9 July 2018

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Nicotinamide Mononucleotide, a Key NAD Intermediate, Treats the Pathophysiology of Diet- and Age-Induced Diabetes in Mice

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation

9 July 2018

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9 July 2018

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Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice

9 July 2018

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SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism

9 July 2018

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9 July 2018

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9 July 2018

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GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response

9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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9 July 2018

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Farnesoid X receptor antagonizes nuclear factor kappaB in hepatic inflammatory response

9 July 2018

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The p300 acetylase is critical for ligand-activated farnesoid X receptor (FXR) induction of SHP.

9 July 2018

1 reference

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PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription

9 July 2018

1 reference

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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma

9 July 2018

1 reference

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Inflammation and metabolic disorders

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337071

Coordinated recruitment of histone methyltransferase G9a and other chromatin-modifying enzymes in SHP-mediated regulation of hepatic bile acid metabolism

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337071

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337071

SUMO: a history of modification

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337071

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4337071

PPARs and the complex journey to obesity

9 July 2018

1 reference

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The Logic Linking Protein Acetylation and Metabolism

9 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25425577

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.15252/EMBJ.201489527

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25425577 AND SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25425577 AND SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

25425577

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25425577 AND SRC:MED&resulttype=core&format=json