The novel immunotherapeutic oligodeoxynucleotide IMT504 protects neutropenic animals from fatal Pseudomonas aeruginosa bacteremia and sepsis (Q35105870)

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English	The novel immunotherapeutic oligodeoxynucleotide IMT504 protects neutropenic animals from fatal Pseudomonas aeruginosa bacteremia and sepsis	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

The novel immunotherapeutic oligodeoxynucleotide IMT504 protects neutropenic animals from fatal Pseudomonas aeruginosa bacteremia and sepsis (English)

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

0 references

1 reference

based on heuristic

inferred from title

Pseudomonas aeruginosa

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based on heuristic

inferred from title

2

object named as

Steven M Opal

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Europe PubMed Central

PubMed publication ID

6 August 2017

8

object named as

John E Palardy

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Europe PubMed Central

PubMed publication ID

6 August 2017

author name string

Abdullah Chahin

1

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Europe PubMed Central

PubMed publication ID

6 August 2017

Jorge Zorzopulos

3

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Europe PubMed Central

PubMed publication ID

6 August 2017

David V Jobes

4

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Europe PubMed Central

PubMed publication ID

6 August 2017

Yazan Migdady

5

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Europe PubMed Central

PubMed publication ID

6 August 2017

Michelle Yamamoto

6

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

Nicholas Parejo

7

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Europe PubMed Central

PubMed publication ID

6 August 2017

David L Horn

9

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6 August 2017

language of work or name

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publication date

15 December 2014

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Europe PubMed Central

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6 August 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

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6 August 2017

59

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Europe PubMed Central

PubMed publication ID

6 August 2017

2

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Europe PubMed Central

PubMed publication ID

6 August 2017

1225-1229

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Europe PubMed Central

PubMed publication ID

6 August 2017

Is boosting the immune system in sepsis appropriate?

1 reference

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9 July 2018

Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis

1 reference

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9 July 2018

Non-clinical safety studies of IMT504, a unique non-CpG oligonucleotide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335857

9 July 2018

The next generation of sepsis clinical trial designs: what is next after the demise of recombinant human activated protein C?*.

1 reference

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A randomized trial of protocol-based care for early septic shock

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Protecting against post-influenza bacterial pneumonia by increasing phagocyte recruitment and ROS production.

1 reference

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9 July 2018

B and T lymphocyte attenuator expression on CD4 T-cells associates with sepsis and subsequent infections in ICU patients

1 reference

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1 reference

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9 July 2018

Carbapenem resistant Enterobacteriaceae carrying New Delhi metallo-β-lactamase gene (NDM-1) in Taiwan

1 reference

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9 July 2018

Sepsis definitions: time for change

1 reference

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9 July 2018

Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012

1 reference

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9 July 2018

Systemic administration of TLR3 agonist induces IL-7 expression and IL-7-dependent CXCR3 ligand production in the lung

1 reference

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9 July 2018

Characterization of Enterobacteriaceae producing OXA-48-like carbapenemases in the UK.

1 reference

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9 July 2018

Mechanisms of fluoroquinolone resistance in Escherichia coli isolates from food-producing animals

1 reference

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9 July 2018

Recent advances in the treatment of Pseudomonas aeruginosainfections in cystic fibrosis

1 reference

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9 July 2018

Emergence of Klebsiella pneumoniae carbapenemase-producing bacteria

1 reference

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9 July 2018

Outbreak of colistin-resistant, carbapenem-resistant Klebsiella pneumoniae in metropolitan Detroit, Michigan

1 reference

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9 July 2018

Immunotherapy for sepsis--a new approach against an ancient foe.

1 reference

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9 July 2018

Active immunization with a detoxified endotoxin vaccine protects against lethal polymicrobial sepsis: its use with CpG adjuvant and potential mechanisms

1 reference

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9 July 2018

Sepsis associated with immunosuppressive medications: an evidence-based review

1 reference

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9 July 2018

CpG motifs in bacterial DNA and their immune effects

1 reference

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9 July 2018

Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae

1 reference

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9 July 2018

Increased plasma levels of interleukin-6 in sepsis

1 reference

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9 July 2018

Inhibition of efflux pumps in methicillin-resistant Staphylococcus aureus and Enterococcus faecalis resistant strains by triterpenoids from Momordica balsamina

1 reference

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27 September 2018

Oligonucleotide IMT504 induces an immunogenic phenotype and apoptosis in chronic lymphocytic leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4335857

27 September 2018

Strong Cytosine-Guanosine-Independent Immunostimulation in Humans and Other Primates by Synthetic Oligodeoxynucleotides with PyNTTTTGT Motifs

1 reference

https://pubmed.ncbi.nlm.nih.gov/25512413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IMT504, the prototype of the immunostimulatory oligonucleotides of the PyNTTTTGT class, increases the number of progenitors of mesenchymal stem cells both in vitro and in vivo: potential use in tissue repair therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/25512413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A high dose of IMT504, the PyNTTTTGT prototype immunostimulatory oligonucleotide, does not alter embryonic development in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25512413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25512413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Addition of the immunostimulatory oligonucleotide IMT504 to a seasonal flu vaccine increases hemagglutinin antibody titers in young adult and elder rats, and expands the anti-hemagglutinin antibody repertoire

1 reference

https://pubmed.ncbi.nlm.nih.gov/25512413

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.03923-14

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

6 August 2017

ResearchGate publication ID

0 references

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