Interspecies pharmacokinetics and in vitro metabolism of SQ109. (Q35100649)

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15 January 2020

title

Interspecies pharmacokinetics and in vitro metabolism of SQ109 (English)

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15 January 2020

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1

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15 January 2020

author name string

Patricia E Noker

2

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15 January 2020

Lori Coward

3

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15 January 2020

Gregory S Gorman

4

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15 January 2020

Marina Protopopova

5

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15 January 2020

Joseph E Tomaszewski

6

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15 January 2020

language of work or name

English

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publication date

1 March 2006

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British Journal of Pharmacology

15 January 2020

published in

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volume

147

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issue

5

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15 January 2020

page(s)

476-485

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Pharmacoproteomic effects of isoniazid, ethambutol, and N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine (SQ109) on Mycobacterium tuberculosis H37Rv

15 January 2020

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Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug

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Applying the biopharmaceutics classification system to veterinary pharmaceutical products. Part II. Physiological considerations

9 July 2018

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Inhibition by ticlopidine and its derivatives of human liver cytochrome p450. Mechanism-based inactivation of CYP 2C19 by ticlopidine.

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The catalytic pathway of cytochrome p450cam at atomic resolution

9 July 2018

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Ticlopidine decreases the in vivo activity of CYP2C19 as measured by omeprazole metabolism

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Pharmacokinetics of antibiotics in natural and experimental superficial compartments in animals and humans

9 July 2018

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Interspecies variation in liver weight, hepatic blood flow, and antipyrine intrinsic clearance: Extrapolation of data to benzodiazepines and phenytoin

9 July 2018

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Simultaneous estimation of pharmacokinetic properties in mice of three anti-tubercular ethambutol analogs obtained from combinatorial lead optimization.

9 July 2018

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The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective

27 September 2018

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Combinatorial lead optimization of [1,2]-diamines based on ethambutol as potential antituberculosis preclinical candidates

27 September 2018

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Carbendazim: disposition, cellular permeability, metabolite identification, and pharmacokinetic comparison with its nanoparticle.

27 September 2018

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Development of a high throughput equilibrium dialysis method

27 September 2018

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Equilibrium dialysis, ultrafiltration, and ultracentrifugation compared for determining the plasma-protein-binding characteristics of valproic acid.

27 September 2018

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Theoretical Relationships between Area under the Curve and Route of Administration of Drugs and Their Precursors for Evaluating Sites and Pathways of Metabolism

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12 December 2020

Physiological parameters in laboratory animals and humans

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12 December 2020

S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

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12 December 2020

Toward a new therapy for tuberculosis

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12 December 2020

Ticlopidine inhibition of phenytoin metabolism mediated by potent inhibition of CYP2C19*

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12 December 2020

Extensive Binding of the Bioflavonoid Quercetin to Human Plasma Proteins

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0706650

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15 January 2020

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15 January 2020

PubMed publication ID

16432511

1 reference